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Sputnik V: fraudulent clinical trial data

forbetterscience.com

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Re: Sputnik V: fraudulent clinical trial data

#51

I think that what is sort of a sideline in this article is really a more important story. The Lancet and NEJM have completely debased themselves and destroyed centuries of institutional credibility in their handling of covid related research. I don't know where it goes from here but they have both burned themselves to the ground.

And the letter dismissing the lab leak theory. https://en.wikipedia.org/wiki/The_Lancet#February_2020_lette...

Re: Sputnik V: fraudulent clinical trial data

#53
post #47

Earlier quoted context omitted.

Yes, you are right. So either way, these vaccines has not passed through proper safety evaluation. Just because something is not possible, does not make it any less required.

> Just because something is not possible, does not make it any less required. Yes, it does.

No it does not.

Because that would be like saying, just because all you got is a binocular with very limited magnification/resolving power, satelites for jupiter does not exist, because you cannot see them through it.

Someone should name this fallacy.

Re: Sputnik V: fraudulent clinical trial data

#54
As the tone of article is bit aggressive, I have own observations, my relatives who lives in Russia were fully vaccinated with Sputnik and all 4 of them (one family) got a very hard COVID with delta, two of them were on oxygen therapy. Doesn’t mean anything but my feelings are that there are some lie about that vaccine efficiency for no reason except political benefits.

Re: Sputnik V: fraudulent clinical trial data

#55
post #47

Earlier quoted context omitted.

Yes, you are right. So either way, these vaccines has not passed through proper safety evaluation. Just because something is not possible, does not make it any less required.

> Just because something is not possible, does not make it any less required. Yes, it does.

It absolutely is possible to retain a control group when developing a vaccine for a disease with CFR and R0 markedly lower than that of the measles. In fact they even had it, until January.

Re: Sputnik V: fraudulent clinical trial data

#56
post #9

This link overly politised and does not offer technical details about these problems. The Moscow Times article [1] makes a better job. [1] https://www.themoscowtimes.com/2021/08/20/leaked-sputnik-v-r...

The submitted link considers the Moscow Times article and copies verbatim (in the leaked report section) the quotes regarding randomization and side effects.

Re: Sputnik V: fraudulent clinical trial data

#57
The article shows evidence of sloppiness, not really of fraud. Neither would really surprise me, given the high political stakes. But I suspect that if Russia went for full-on fraud, they would do a much better job than this.

Case in point: the doping scandal at the Sochi winter olympics. It was evil, yes, but you cannot help but admire how detailed and well-executed the operation was. They designed and built a whole building around the scheme! Supposedly, even the FSB (reincarnation of KGB) was involved. If not for a senior whistle-blower, I think we would never know.

I'm sure that if there was some top-level prikaz to cook the books, there would be no discernible flaws in the data whatsoever.

Re: Sputnik V: fraudulent clinical trial data

#58
post #6

Earlier quoted context omitted.

Same feeling here. Curiously enough the domain is called "For better science", where we'd have expected neutrality and impartiality to be the guiding principles of any report. Apart from that, it is hard to believe that any of the vaccine reports and clinical trials are unbiased. Unfortunately there are too many conflicts of interest and money on the table for any information to be taken at face value. The beauty of…

>The beauty of science is that now that the vaccines are out there it becomes easier to independently access them and move our knowledge further in the right direction. Can you clarify what you mean by this?

I mean that groups without any conflict of interest can gather population level data and evaluate for themselves how effective the vaccines are, and how likely it is for the clinical trial data to have been correct. There is a reason publications and conferences require disclosure of conflicts of interest, and that is because those with a conflict of interest are biased to find positive results (and hide negative results) that align with their financial goals.

Re: Sputnik V: fraudulent clinical trial data

#59
post #58

Earlier quoted context omitted.

>The beauty of science is that now that the vaccines are out there it becomes easier to independently access them and move our knowledge further in the right direction. Can you clarify what you mean by this?

I mean that groups without any conflict of interest can gather population level data and evaluate for themselves how effective the vaccines are, and how likely it is for the clinical trial data to have been correct. There is a reason publications and conferences require disclosure of conflicts of interest, and that is because those with a conflict of interest are biased to find positive results (and hide negative res…

>I mean that groups without any conflict of interest can gather population level data and evaluate for themselves how effective the vaccines are,

It won't work because for every such group, there will be 10 groups with high conflict of interest that can counter any finding of your hypothetical group, and journals with conflict of interests will reject the findings of that group, but instead give high visibility to the reports of high-conflict of interest groups..

Quickly no one will dare to research the said topic.

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