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SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

biorxiv.org

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Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#21

Post by tstrimple »

Jaruzel wrote: post #17
tstrimple wrote: post #5

Earlier quoted context omitted.

You're more than twice as likely to be reinfected if you have immunity through previous infection. Vaccine protection is significantly better. https://www.news-medical.net/news/20210811/COVID-19-vaccines...

I seriously doubt this is correct. Covid has 3 protein markers. After you get infected your antibodies will continue to recognise all three. However the vaccines don't have all three, so the antibodies generated are not as all encompassing as they would be if you contracted Covid. Therefore, if it doesn't kill you, having Covid puts you in a better position to fight off variants. At least that's how I understand it f…

Speculation from a random stranger on the internet, or a study showing results? I'll take the study with the results.

https://www.cdc.gov/mmwr/volumes/70/wr/mm7032e1.htm?s_cid=mm...

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#22

Post by OniBait »

Jaruzel wrote: post #17
tstrimple wrote: post #5

Earlier quoted context omitted.

You're more than twice as likely to be reinfected if you have immunity through previous infection. Vaccine protection is significantly better. https://www.news-medical.net/news/20210811/COVID-19-vaccines...

I seriously doubt this is correct. Covid has 3 protein markers. After you get infected your antibodies will continue to recognise all three. However the vaccines don't have all three, so the antibodies generated are not as all encompassing as they would be if you contracted Covid. Therefore, if it doesn't kill you, having Covid puts you in a better position to fight off variants. At least that's how I understand it f…

You are correct. Both links that he posted are talking about reinfection. So prior infection + vaccine > infection (no vaccine) > vaccine only > no infection/no vaccine.

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#23

Post by ASalazarMX »

newacct583 wrote: post #15
thinkharderdev wrote: post #11

FYI. Higher immune resistance in this paper is relative the D614G (the original parent of all variants, so not the original Wuhan strain). As far as I understand Lambda is less immune/vaccine resistant than Delta and has been mostly outcompeted by Delta.

Indeed, lambda doesn't seem to be growing vs. delta anywhere. It's so frustrating to watch the media fall into this trap, just google "lambda covid" and you'll find a flood of breathless headlines about this "new dangerous variant" and like no warnings from any experts at all.

A significant part of news media has devolved into a curse for humanity. Their main objective is getting eyeballs, so their headlines have become anxiety-inducing. Anxious people check the news more often.

Their ultimate objective earning money with ads/publicity, so maybe that curse boils down (again) to advertisement.

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#24

Post by joshuakelly »

tstrimple wrote: post #21
Jaruzel wrote: post #17

Earlier quoted context omitted.

I seriously doubt this is correct. Covid has 3 protein markers. After you get infected your antibodies will continue to recognise all three. However the vaccines don't have all three, so the antibodies generated are not as all encompassing as they would be if you contracted Covid. Therefore, if it doesn't kill you, having Covid puts you in a better position to fight off variants. At least that's how I understand it f…

Speculation from a random stranger on the internet, or a study showing results? I'll take the study with the results. https://www.cdc.gov/mmwr/volumes/70/wr/mm7032e1.htm?s_cid=mm...

After this legitimation crisis, sorry, but articulate strangers are often the best way to "read the headlines upside down" - a necessary fact of life now.

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#25

Post by api »

xienze wrote: post #7
jaywalk wrote: post #2

Interesting that they only studied vaccine-induced immunity. Not a single word about natural immunity.

> Not a single word about natural immunity. There’s major, major hesitance to giving natural immunity any credibility. The reason for that is an exercise left up to the reader.

The irony is that if it weren't for quacks and anti-vax idiots we would not have to exercise such hesitancy.

Sort of like how we could talk about genetics and IQ if it were not for racists. I could list a dozen more like this.

We now have to whisper about certain topics for fear of providing anything that can be quoted out of context and twisted by bad faith actors to promote destructive nonsense.

I personally think the best option might be to slather these topics with such thick academic and technical jargon that papers and messages about them contain nothing that can be quoted in a meme and shared on Facebook.

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#26

Post by ASalazarMX »

xienze wrote: post #7
jaywalk wrote: post #2

Interesting that they only studied vaccine-induced immunity. Not a single word about natural immunity.

> Not a single word about natural immunity. There’s major, major hesitance to giving natural immunity any credibility. The reason for that is an exercise left up to the reader.

Immunity is complex. If it were simple, a single flu/cold would make you immune to all.

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#27

Post by raphlinus »

tstrimple wrote: post #12
js290 wrote: post #8

Earlier quoted context omitted.

https://threadreaderapp.com/thread/1420130581426364416.html

Cool, you counter a news article backed by a study with a tweet backed by screenshots of headlines. Seems totally reasonable.

Not only that, but a tweet from someone who has earned the title, "the pandemic's wrongest man".

ETA: And to critique the substance and not the messenger, I have tried to track down any publication of the Israeli Health Ministry that contains data supporting this claim, and have failed to do so. All traces lead to a story in the Israel National News, which gives no specifics about the source of the data, just lots of numbers to support the conclusion that vaccines don't work well. There's a good chance all this is just fabricated.

If you can cite a report by the Israeli Health Ministry and provide an analysis supporting the claim that doesn't contain an obvious statistical error (wrong denominator being the one I suspect), then I will apologize abjectly and donate $1000 to the charity of your choice.

[1]: https://www.theatlantic.com/ideas/archive/2021/04/pandemics-...

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#28

Post by js290 »

tstrimple wrote: post #12
js290 wrote: post #8

Earlier quoted context omitted.

https://threadreaderapp.com/thread/1420130581426364416.html

Cool, you counter a news article backed by a study with a tweet backed by screenshots of headlines. Seems totally reasonable.

you're a "hacker"... use the interwebz to find the original study... or do you need Snopes to do that for you?

Re: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

#30

Post by DiogenesKynikos »

xienze wrote: post #7
jaywalk wrote: post #2

Interesting that they only studied vaccine-induced immunity. Not a single word about natural immunity.

> Not a single word about natural immunity. There’s major, major hesitance to giving natural immunity any credibility. The reason for that is an exercise left up to the reader.

Because the virus is dangerous. If you have the choice of getting immunity though a vaccine or by catching the virus, you should pick the vaccine. The whole point of immunity is not to get infected/sick in the first place. Getting infected so that you can become immune makes no sense at all.
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