Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
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Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#2Can any of the findings from the properties of how natural immunity works be guided in to future COVID 19 vaccines?
Given how the pharma companies are examining anti-body half life, exploring booster shots, and considering vaccinations against variants (like lambda), can any of the learnings go into a more durable, more broad vaccine?
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#3Just a note to non-immunologists - Immunity means different things to health and science professionals vs the general public.
Edit: I'm not going into detail in this comment because I am not an immunologist and I cannot express clearly and correctly what the difference is, but just be aware that "Immunity" may not mean 100% protection in the way that the general public thinks that word means.
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#4Just a note to non-immunologists - Immunity means different things to health and science professionals vs the general public. Edit: I'm not going into detail in this comment because I am not an immunologist and I cannot express clearly and correctly what the difference is, but just be aware that "Immunity" may not mean 100% protection in the way that the general public thinks that word means.
Don’t leave us hanging - what does it mean?
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#5Can any of the findings from the properties of how natural immunity works be guided in to future COVID 19 vaccines? Given how the pharma companies are examining anti-body half life, exploring booster shots, and considering vaccinations against variants (like lambda), can any of the learnings go into a more durable, more broad vaccine?
https://www.nature.com/articles/s41586-021-03738-2
did it already.
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#6https://www.nature.com/articles/s41586-021-03738-2
vaccines also produce durable and persistent immune responses. Primary antibody titers wane, but the system itself remembers and can regenerate them when challenged.
see https://news.ycombinator.com/item?id=28107714 for contra "but muh boosters", which i suspect is what's helping me collect downvotes.
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#7Can any of the findings from the properties of how natural immunity works be guided in to future COVID 19 vaccines? Given how the pharma companies are examining anti-body half life, exploring booster shots, and considering vaccinations against variants (like lambda), can any of the learnings go into a more durable, more broad vaccine?
https://www.nature.com/articles/s41586-021-03738-2 did it already.
I think GP is referring to the fact that boosters are being pushed, which implies vaccine immunity is not persistent. It has certainly been pushed since when that study was published.
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#8Earlier quoted context omitted.
https://www.nature.com/articles/s41586-021-03738-2 did it already.
I think GP is referring to the fact that boosters are being pushed, which implies vaccine immunity is not persistent. It has certainly been pushed since when that study was published.
we still need the primary antibody count up high, because we’re still in a pandemic, thus the desire for boosters.
in both vaccine induced and survivor induced immune responses, long term immune systems come online to store a memory of the disease so that on future challenge, more of those antibodies will be produced by people fairly rapidly after future exposure, even when your blood stream isn’t full of covid antibodies anymore.
When there are this many cases floating around, though, you can't afford to wait for the spin-up time.
If i'm asking for the same image every 500ms from your webserver, do you want to go to disk every damn time, or are you gonna cache it? Same deal, kinda.
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#9https://www.nature.com/articles/s41586-021-03738-2 vaccines also produce durable and persistent immune responses. Primary antibody titers wane, but the system itself remembers and can regenerate them when challenged. see https://news.ycombinator.com/item?id=28107714 for contra "but muh boosters", which i suspect is what's helping me collect downvotes.
Natural immunity may work better considering the vaccine requires booster shots every 12 months according to the Pfizer CEO.
https://www.cnbc.com/2021/04/15/pfizer-ceo-says-third-covid-...
Re: Longitudinal analysis shows durable immune memory after SARS-CoV-2 infection
#10https://www.nature.com/articles/s41586-021-03738-2 vaccines also produce durable and persistent immune responses. Primary antibody titers wane, but the system itself remembers and can regenerate them when challenged. see https://news.ycombinator.com/item?id=28107714 for contra "but muh boosters", which i suspect is what's helping me collect downvotes.
Please stop spreading misinformation. IMO 15 weeks is not long enough to determine if its durable and persistent. There would be no talk of booster shots if what your saying is true.