Earlier quoted context omitted.
> because then everything is nicely isolated This is why we use SQLite for all the things. I don't even remember what a database installation process looks like anymore. It's just a nuget dependency and some code for us.
Are you using SQLite in production too? I'm curious about your domain - is it a web application or something else?
We use it as part of the back-end of a business workflow automation system. Handles 100-1000 concurrent users without any issues.