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Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

reuters.com

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Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#5
It's obvious we need booster vaccinations. But not another intramuscular that only seeps in serum IgG antibodies into the lower lungs. The levels of antibodies in the upper respiratory mucosa are never very high and drop rapidly. Viral infection of the mucosa and shedding still occurs.

We need operation warp speed type money for funding the two good intranasal sars-cov-2 vaccine trials going on right now and to start more. Intranasal vaccination after intramuscular will recruit and specialize B and T cells to the upper respiratory mucosa and establish IgA antibodies resident for long periods there. Being intranasally vaccinated after intramuscular could actually stop the spread and end the pandemic.

edit: btw, all this has been known about aerosol spread respiratory viruses and human physiology since the 1960s.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#6

Pfizer shouldn't be allowed to state publicly their opinion on this. Huge conflict of interests

I disagree that they shouldn’t be able to state their option, they should be able to.

But no one should believe them or take what they say at face value.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#7
Yes sales... sales from insanely binding contracts which of course say Pfizer is in no way shape or form responsible for anything that goes wrong with highly experimental, largely untested and rushed through drugs with completely unknown long-term side effects... that states companies are not allowed to return or take partial shipments of their vaccines...which PFIZER ITSELF dictates how many units the labs and medical facilities are going to buy. So 33b from using a global pandemic to rig and rip the entire supply chain, medical industry, and taxpayers of countries around the world off to insane levels of profit, all in the name of greed.. And yet here they are, demanding MORE money...

And yet people still sit around trying to click two brain cells together wondering why people refuse to get vaccinated, are sick of having this crap shoved down their throats, and further distrust big pharma and the medical industry at large.

Can't wait for the big pharma shills here on HN to come crawling out defending these scumbags and big industries and institutional corruption and greed.

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#8
post #3

Earlier quoted context omitted.

How so?

There is a strong economic incentive to press for recurring boosters.

If they were the ones making the decision I'd have a problem. Just stating their opinion without any attempt to claim it's objective seems... fine. I'd personally be pretty surprised if my government (UK) authorised a 3rd booster dose of the same formula (as opposed to one that adjusted the formula to better target new variants).

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#9
Party might be ending for Pfizer if this early report plays out as stated and data shows viral blood titers are being found to have higher loads in the vaccinated vs non vaxxed.

It would suggest the worst nightmare for a vaccine, ADE could be happening.

From NBC Twitter: New data suggests that fully vaccinated individuals are not just contracting COVID, but could be carrying higher levels of virus than previously understood, facilitating spread, my NBC News colleagues are reporting. New indoor masking guidance expected today. https://twitter.com/KenDilanianNBC/status/142002439326320640...

https://en.m.wikipedia.org/wiki/Antibody-dependent_enhanceme...

(Edit, added note about viral blood tigers being needed for confirmation)

Re: Pfizer says 2021 Covid-19 vaccine sales to top $33.5 bln, sees need for boosters

#10
Would they be able to tweak this potential booster shot to better target current variants and their descendants? Is there any need to do so?

How much about the current vaccine can possibly be changed without major regulatory hurdles or manufacturing blockers?

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