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Schizophrenia linked to marijuana use disorder is on the rise, study finds

cnn.com

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Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#311

Post by mcguire »

Original paper: "Development Over Time of the Population-Attributable Risk Fraction for Cannabis Use Disorder in Schizophrenia in Denmark" (https://jamanetwork.com/journals/jamapsychiatry/article-abst...)

"Question Has the population-attributable risk fraction for cannabis use disorder in schizophrenia increased over time, as would be expected with increasing use and potency of cannabis?

"Findings In this Danish nationwide, register-based cohort study, the population-attributable risk fraction for cannabis use disorder in schizophrenia increased from approximately 2% in the period to 1995 to approximately 6% to 8% since 2010.

"Meaning These findings may indicate that cannabis use disorders are associated with an increase in the proportion of cases of schizophrenia.

"* The results from these longitudinal analyses show the proportion of cases of schizophrenia associated with cannabis use disorder has increased 3- to 4-fold during the past 2 decades, which is expected given previously described increases in the use and potency of cannabis. This finding has important ramifications regarding legalization and control of use of cannabis.*"

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#312

Post by sunnytimes »

01100011 wrote: post #139
lrdswrk00 wrote: post #111

Earlier quoted context omitted.

Daily toker and edible eater; I’m high now. Hit the bong and a cartridge multiple times. I’ve also successfully upgraded large chunks of my employers infra code; tests green, deploys green. It’s no different than coffee to me at this point; I figured out working with those jitters and anxiety. I even saw shimmering with caffeine I’ve never seen on THC. I’m pretty sure a whole lot of the behavior is just subculture st…

Sort of sounds like me a decade ago. If you find yourself still doing the same job in a decade, I think you'll know why. Tech jobs are very compatible with weed. The sort of tactical, short term thinking you need to apply current knowledge to problems works well. It's great for crafting clever, short-term solutions and hacking your way through things. If that's all you ever want to be, smoke weed everyday man, why no…

meh .. my friend and i started what is now a multi million dollar company over the past 15 years and we smoke weed everyday .. we smoke at work , just only after 5 .. no one is pushing me out into a street cause i smoke pot , quite the opposite actually.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#313

Post by kayodelycaon »

riemannzeta wrote: post #135
jklinger410 wrote: post #88

Earlier quoted context omitted.

Untreated neuro-divergent people tend to use recreational drugs for medicinal purposes. And psychoactive drug usage is directly linked with the early onset of otherwise dormant schizophrenia, as well as a myriad of other mental disorders. There is no science to state that psychoactives cause these mental disorders. In fact, current medical science states the opposite, that psychoactives do NOT cause, but exacerbate,…

Presented for your consideration without comment: https://adai.uw.edu/pubs/pdf/2017mjbipolar.pdf

Pretty standard study that showing two things are correlated. The THC/CBD chart is misleading because none of the data is actually used to form the conclusions.

The interesting thing is the "Use of Marijuana to Self-Medicate BD" study is useless. Monitoring a small number of bipolar people for 6 days will give you completely random results. It's too short a period to remove moods from the equation.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#314

Post by moate »

Tl;dr- People who have Schizophrenia are more frequently found to also have marijuana use disorder than before.

Correlation. This is not been proven causal (which, btw why is it never phrased such that “people inclined towards schizophrenia are more inclined to abuse drugs” which seems like a pretty obvious line to me but I just work in medical publishing, I’m not the actual doctor).

Remember everyone: someone is funding all research, often times they have an agenda and a good press agent when they get some results they like. That said, this piece very specifically says “we can’t conclude a causal relationship, we need further research” (or, more specifically, funding for our research)

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#315

Post by bjourne »

jbuhbjlnjbn wrote: post #233
amanaplanacanal wrote: post #213

Earlier quoted context omitted.

Yes. Typically when I was young, you kept smoking until you reached the desired level of intoxication then stopped. Do people do it differently now?

Exactly. The narrative of the "stronger, more dangerous(!) weed" falls short because consumers have always, and will always, micro-dose. That's just the human way to do it. You don't drink 1l of water when you are thirsty, you drink until the body tells you it is enough. You don't eat until the food is empty (ok well, sometimes we do..), you eat until you are full. I find it disappointing the same'ol propaganda reapp…

I find it disappointing and disheartening that you are dismissing peer-reviewed studies as "propaganda". Your argumentation is not that different from the one used by climate change deniers.

The first study is commissioned by the European Monitoring Centre for Drugs and Drug Addiction and the second was funded by a Senior Academic Fellowship from the Society for the Study of Addiction.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#316

Post by tudorw »

okareaman wrote: post #169
rantwasp wrote: post #97

Earlier quoted context omitted.

Since we’re here I would like to see a study linking sugar to the increase of health problems (including mental health). Other drugs are small change compared to sugar.

I recently gave up sugar when I realized I suffered sugar highs/withdrawal depressions and reached for it when I felt anxious, just like a drug. https://www.medicalnewstoday.com/articles/318818

Food As A Machine Gun (Official Lyric Video) - Enemy Radio, Public Enemy

https://www.google.com/search?gs_ssp=eJzj4tVP1zc0TCtJMra0yDY...

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#317

Post by watwut »

SquishyPanda23 wrote: post #189
macksd wrote: post #47

>> In 1995, 2% of schizophrenia diagnoses in the country were associated with cannabis use disorder. In 2000, it increased to around 4%. Since 2010, that figure increased to 8%, the study found. Worded that way, causation isn't the first thing this suggests to me. If percentage of cases associated with marijuana rise, it could also be that a larger percentage of the population is smoking and admitting to smoking mari…

> It could very well be that marijuana puts you at higher risk of schizophrenia More likely, marijuana use accelerates the development of schizophrenia among people already at risk. > it could also be increases in the percentage of cases that actually get diagnosed, etc. This is generally a valid stock response to these sorts of studies. But it strikes me as a bit unlikely that there was previously a large amount of…

> But it strikes me as a bit unlikely that there was previously a large amount of undiagnosed schizophrenia.

Why would that be unlikely?

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#318

Post by heavyset_go »

theshadowknows wrote: post #265

I smoked weed the first time when I was 15 or so. A buddy of mine bought some from a friend of a friend. And we continued to smoke mostly on weekends for years. I stopped right around college in 2007 or so. Then a year or so ago I smoked some legal weed from a dispensary. And that shit almost killed me. I was nauseated and sweating and I vomited repeatedly for like two hours. And I couldn’t control my thoughts. They…

Tolerance makes a big difference. If you haven't smoked in a long time, you'll be sensitive to even small amounts of marijuana and it doesn't take much to be too much.

I suspect that cannabinoids and the cannabinoid system act somewhat like the opioid system, where the brain will react differently to the substances depending on tolerance. In the latter system, chronic opioid usage changes the sedative effects associated with that class of drugs to stimulant-like effects.

Similarly, people with no THC tolerance who consume it get anxiety as a side effect, but for chronic users, they get anxiolytic responses from it.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#319

Post by dkn775 »

CAX wrote: post #207

Most obvious schizophrenics i have come across were not drug users and were just frightened supicious people who couldnt navigate a social interaction including but not limited to food deliveries, drug deliveries, buying batteries etc. I think the uptick in noticed drug user psychosis is Related to something Big Bill Orielly warned us about: the confluence of drugs and technology, esp social media, implying not takin…

Can you provide a link to oriellys talk on that

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#320

Post by da_big_ghey »

gwern wrote: post #176
kvathupo wrote: post #16

As usual, a sensational headline averring a research article's causal hypothesis, of which the PI even calls for reproducibility. Reading such paltry science articles makes me really appreciate papers like Quanta, whose reporters seem to actually have a semblance of domain knowledge. Indeed, no discussion of the existing link between schizophrenia and tobacco smoking, in conjunction with the increased availability of…

The population level prevalence is where we should see this. If cannabis really did cause SCZ, as opposed to merely being self-medication, general drug use dysfunctionality, or possibly just accelerating SCZ onset but not increasing total cases, we should see incredibly high rates in recreational legalizing jurisdictions where prevalence is now a large fraction of the population. Instead, buried at the end, we get "T…

not in necesity: maybe heavy users are using with or without law, maybe law mostly causing casual users to use it but not many more heavy ones. If then only heavy use is cause schizofrenia, we maybe are not seeing a great growth of rates.
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