Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Cannabis first domesticated 12,000 years ago

phys.org

Post reply on HN
Print view View original

21–30 of 74 posts

Re: Cannabis first domesticated 12,000 years ago

#21

Post by erdos4d »

deregulateMed wrote: post #4

Since this is the first cannabis topic I've seen on HN, I have lots of questions/ideas/problems I want to share. I'm going to post them in no particular order. Maybe someone has a solution >I like weed as a productive drug, it's stronger than caffeine for me, but I develop tolerance and addiction quickly. Any solution to the tolerance problem? Quitting/breaks is obvious. >Is investing in weed stocks encouraging drug…

I know this sounds bad, but the addiction aspect can be mitigated by living life and being in positions where you need to quit smoking numerous times for whatever reasons. You learn how to master the desire. With that said, I also agree with you that it is a wonderful productivity drug. I can reliably get 2X done in a day if I add a small amount of cannabis.

Re: Cannabis first domesticated 12,000 years ago

#22

Post by EvRev »

deregulateMed wrote: post #4

Since this is the first cannabis topic I've seen on HN, I have lots of questions/ideas/problems I want to share. I'm going to post them in no particular order. Maybe someone has a solution >I like weed as a productive drug, it's stronger than caffeine for me, but I develop tolerance and addiction quickly. Any solution to the tolerance problem? Quitting/breaks is obvious. >Is investing in weed stocks encouraging drug…

>Is there a solution to munchies?

Lookup THCV, it is an analog that decreases your appetite along with a host of other benefits. Like you can consume any type of cannabis and then take a little THCV to counteract the munchies.

Re: Cannabis first domesticated 12,000 years ago

#23

Post by dboreham »

robbedpeter wrote: post #3

This coincides with the Dryas impact era - there seems to be a lot of cultural advances, settlements, and other artifacts that pop up around that time. It seems very plausible to me that many of the discoveries aren't the first of their kind, but the first reimplementation after humans began to rebuild. The Dryas impact is a fascinating event - if validated, it has the potential to shake up a lot of the currently acc…

On my todo list for a while has been to dig down to see if I can find the "black mat".

Re: Cannabis first domesticated 12,000 years ago

#24

Post by mountainriver »

EvRev wrote: post #22
deregulateMed wrote: post #4

Since this is the first cannabis topic I've seen on HN, I have lots of questions/ideas/problems I want to share. I'm going to post them in no particular order. Maybe someone has a solution >I like weed as a productive drug, it's stronger than caffeine for me, but I develop tolerance and addiction quickly. Any solution to the tolerance problem? Quitting/breaks is obvious. >Is investing in weed stocks encouraging drug…

>Is there a solution to munchies? Lookup THCV, it is an analog that decreases your appetite along with a host of other benefits. Like you can consume any type of cannabis and then take a little THCV to counteract the munchies.

Yeah I don’t think we’ve tapped thcv yet, often called the sports car of cannabis

Re: Cannabis first domesticated 12,000 years ago

#25

Post by irthomasthomas »

mallomarmeasle wrote: post #14
deregulateMed wrote: post #4

Since this is the first cannabis topic I've seen on HN, I have lots of questions/ideas/problems I want to share. I'm going to post them in no particular order. Maybe someone has a solution >I like weed as a productive drug, it's stronger than caffeine for me, but I develop tolerance and addiction quickly. Any solution to the tolerance problem? Quitting/breaks is obvious. >Is investing in weed stocks encouraging drug…

Medicinal Chemist (and former cannabis consumer) here. >I like weed as a productive drug, it's stronger than caffeine for me, but I develop tolerance... Interestingly, I used to notice that once I became tolerant to one strain, over a couple weeks, switching to another strain could at least partially alleviate it. This to me is fascinating. Psychoactive effects of cannabinoids are thought to be mediated by the CB1 re…

"In 1998, Professors Raphael Mechoulam and Shimon Ben-Shabat posited that the endocannabinoid system demonstrated an “entourage effect” in which a variety of “inactive” metabolites and closely related molecules markedly increased the activity of the primary endogenous cannabinoids, anandamide and 2-arachidonoylglycerol"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334252/#:~:tex...

Re: Cannabis first domesticated 12,000 years ago

#26

Post by neom »

robbedpeter wrote: post #3

This coincides with the Dryas impact era - there seems to be a lot of cultural advances, settlements, and other artifacts that pop up around that time. It seems very plausible to me that many of the discoveries aren't the first of their kind, but the first reimplementation after humans began to rebuild. The Dryas impact is a fascinating event - if validated, it has the potential to shake up a lot of the currently acc…

Thanks for posting this, never heard of the event. PBS has a Youtube channel called "Eons" (seems cool)- I watched their video about it and found it super interesting: https://www.youtube.com/watch?v=95u2sk_lRoQ

Re: Cannabis first domesticated 12,000 years ago

#27

Post by neom »

EvRev wrote: post #22
deregulateMed wrote: post #4

Since this is the first cannabis topic I've seen on HN, I have lots of questions/ideas/problems I want to share. I'm going to post them in no particular order. Maybe someone has a solution >I like weed as a productive drug, it's stronger than caffeine for me, but I develop tolerance and addiction quickly. Any solution to the tolerance problem? Quitting/breaks is obvious. >Is investing in weed stocks encouraging drug…

>Is there a solution to munchies? Lookup THCV, it is an analog that decreases your appetite along with a host of other benefits. Like you can consume any type of cannabis and then take a little THCV to counteract the munchies.

Hadn't heard of it but seems interesting, thanks for posting. Here's a good in-depth article about it from a couple of days ago if anyone is interested: https://www.leafly.com/news/cannabis-101/everything-you-need...

Re: Cannabis first domesticated 12,000 years ago

#28

Post by wcchandler »

So glad to see more genomic research around cannabis. I have a jar full of seeds from my late grandfather. He said it was from the same hemp that the Constitution was written on. Doubt the truth behind that but it’d be really cool if one day I could have it analyzed and compared for relatively cheap.

Re: Cannabis first domesticated 12,000 years ago

#29

Post by JohnJamesRambo »

Ironic that the penalty for cannabis possession goes up to death now in the place where it was first domesticated. Death for having a plant that makes people feel good and happy. Humans are weird.

This study is really neat because as the article says the consensus was always Central Asia for the birthplace of cannabis and now we learn that it is East Asia.

Re: Cannabis first domesticated 12,000 years ago

#30

Post by vmception »

robbedpeter wrote: post #3

This coincides with the Dryas impact era - there seems to be a lot of cultural advances, settlements, and other artifacts that pop up around that time. It seems very plausible to me that many of the discoveries aren't the first of their kind, but the first reimplementation after humans began to rebuild. The Dryas impact is a fascinating event - if validated, it has the potential to shake up a lot of the currently acc…

I also generally think the idea of a recently linear progression of human collaboration and advancement is misguided

I think fossilization is merely rare and difficult

Post reply on HN