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Burden of post-Covid-19 syndrome and implications for healthcare planning

journals.plos.org

21–30 of 280 posts

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#22

Correct me if wrong, but this doesn't appear to have a non-Covid-19 control group? This study on Long Covid found there was no statistical difference between teenagers that had Covid compared to those that didn't. Suggesting that these symptoms may be getting entangled and misattributed. https://www.medrxiv.org/content/10.1101/2021.05.11.21257037v...

If you read through the limitations section of the report, you will find they covered this along with several other limitations of the study.

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#23

> Third, we did not have a baseline (pre-COVID-19) assessment of participants’ physical and mental health. Thus, it is impossible to distinguish the effects of COVID-19 from pre-existing conditions. The interpretation of our findings regarding depression and anxiety is further limited by the psychological burden that the pandemic may impose in general [48, 49]. While we tried to compare our results with estimates fro…

> Kind of hard to tell what this result means without a control or baseline

Yes. As pointed out in

Causation or confounding: why controls are critical for characterizing long COVID

https://www.nature.com/articles/s41591-021-01402-w

"To address some of these biases, we and others used established longitudinal cohorts recruited at the start of the pandemic for regular testing for antibodies to SARS-CoV-2 and thus provided objective confirmation of infection. We asked our healthcare-worker participants about 72 symptoms reported to be associated with long COVID, at a median of 7.5 months after the development of COVID-19, and found that mental-health, gastrointestinal and dermatological symptoms were as common among 140 patients with mild-to-moderate symptomatic seropositive COVID-19 (‘cases’) as in 1,160 control participants who remained asymptomatic and seronegative throughout the surveillance period. Of concern, 40–60% of both cases and control participants reported mental-health symptoms, which highlights the toll of pandemic on the healthcare workforce. We also identified three clusters that included 12 symptoms—affecting the sensory, neurological and cardiorespiratory systems—that were reported by 67% of cases but also 44% of control participants, which emphasizes the ongoing difficulties in characterizing long COVID."

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#24
post #3

One of those cases here. Symptoms: suddenly out of energy, occasionally suddenly being unable to spell, even mild physical exercise leaves me floored (and I was pretty fit for my age prior to this). So, 17 months in: it's still not back to where it used to be but if you think of it in terms of trends instead of absolutes it is definitely still improving. The downs are less far down, the fog is lifting and the energy…

Did you try NAC? Maybe worth a shot - this paper is about „long EBV/mono“ which might have similar mechanisms: https://pubmed.ncbi.nlm.nih.gov/29228057/

> These data support the idea that NAC could be considered as a treatment to alleviate chronic inflammatory pathologies, including post-viral disease

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#25
How likely are these numbers to be accurate? This Swiss study of 431 adults gives a 26% incidence of "Long Covid" at 6-8 months.

But another study that I'm more familiar with that tracked 4,182 people (mostly from the U.K., U.S., and Sweden) says only 2.3% of participants reported symptoms past the three month point. [0]

I feel like every time I look into this topic I find a new study with a wildly different estimate.

[0] https://www.nature.com/articles/s41591-021-01292-y

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#26
post #3

One of those cases here. Symptoms: suddenly out of energy, occasionally suddenly being unable to spell, even mild physical exercise leaves me floored (and I was pretty fit for my age prior to this). So, 17 months in: it's still not back to where it used to be but if you think of it in terms of trends instead of absolutes it is definitely still improving. The downs are less far down, the fog is lifting and the energy…

I got CoVid in Osaka at the beginning of November 2019. The symptoms lasted around 5 months. I got it again in May 2021 and this time I was fully recovered in 3 weeks.

I got vaccinated, even during the second infection I felt extremely tired and slightly confused, I want to minimize as much as possible the risk of repeating again.

update: For all the down-votes. Time will say. But "A new study shows that first cases of coronavirus infections could have appeared in China between October and mid-November 2019". It fits with my experience. https://www.dw.com/en/covid-study-cases-spread-in-china-earl...

update 2: I arrived to Osaka Airport (KIX) on 9th November, I had symptoms 3 days later.

update 3: Stop down-voting the people that says that it is impossible. It may be the case, I am just sharing my personal experience in case it clicks somewhere. I can be wrong and it could have been a virus with very similar symptoms. I didn't wanted to start a war of up votes and down votes, that adds nothing to the discussion.

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#27
Self-reported symptoms. And now we will have the litany of hypochondriacs that didn't even got tested for SARS-COV-2 but swear they have some misterious long term viral syndrome that in the real world, if it really exists, is extremely rare.

The trash that passes as science nowadays.....

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#28

Earlier quoted context omitted.

Ah yes, the heart thing. Forgot to mention that because it hasn't happened for a couple of months now but I would wake up at night every now and then with my heart going like I just ran a marathon. But that fortunately completely went away. As for lung capacity: I used to play saxophone pretty fanatically and I think that is one of the reasons I got through this with a relatively low amount of damage.

> As for lung capacity: I used to play saxophone pretty fanatically and I think that is one of the reasons I got through this with a relatively low amount of damage. Funnily enough, I used to play the flute and sing before contracting COVID. With my lung capacity halved, my ability is nowhere near what it used to be. Long COVID has taken all my hobbies away from me: running, singing, hip-hop dancing. If anyone knows…

Gah that sucks, I really feel for you. But: you will recover. For the longest time I thought that I wouldn't and then bit by bit it got better. If you can find an exercise bike I would really recommend you find one, it is super motivating to see your distance creep up day-by-day as you regain your strength and wind.

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#29

Since they claim a quarter of patients are showing symptoms and one of those is depression - how do they separate the out the effect of the de facto criminalization of social activity, an innate human behavior ingrained in our DNA after millions of years of evolution? You'd get significant depression in solitary confinement too.

No idea why you're getting downvoted - they have no control group and as you say there's 'depression' in their symptoms they count for. I'm pretty sure 'depression' (which I'm sure they don't count as clinically depressed, but 'im feeling more depressed') went up significantly in the whole population last year. Also PLoS one is basically not peer reviewed - they accept every paper after a short review.

That part is fine but the part where he instead diagnoses everyone with having been driven crazy by the (by implication misguided) coronavirus response is not really thoughtful in my opinion.

Re: Burden of post-Covid-19 syndrome and implications for healthcare planning

#30
post #3

One of those cases here. Symptoms: suddenly out of energy, occasionally suddenly being unable to spell, even mild physical exercise leaves me floored (and I was pretty fit for my age prior to this). So, 17 months in: it's still not back to where it used to be but if you think of it in terms of trends instead of absolutes it is definitely still improving. The downs are less far down, the fog is lifting and the energy…

You mean your brain was starved of oxygen for some time? (while still enough to not faint)

Interesting, could somebody more knowledgable say if this is possible?

Wish you a swift recovery in any case!

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