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Reminds me of how DNP, a chemical used for creating explosives, has been used as a weight-loss drug. It's surprisingly effective, but overdosing on it will result in a long, hot, agonizing death.
Chemotherapy is basically cave man medicine. That a therapeutic drug is explosive only adds to that sentiment. The idea that we'll basically poison you just up to a point that's nearly fatal in order to kill the cancer is such a terrible way to treat someone. Now I'm not saying don't ever do it -- unfortunately that's where we're at in 2021. It's just kind of unbelievable that cancer remains so elusive that we're sti…
> That a therapeutic drug is explosive only adds to that sentiment. Explosivity and toxicity are unrelated. Cyanide can kill you, but it's not explosive IIRC. You can make explosives with aluminum, but it's safe to use as a food container, ... > Chemotherapy is basically cave man medicine. The main problem is that cancer cells and normal cells are very similar. Anything that kills cancer cells will probably kill norm…
Really? Doesn't something being explosive mean it's highly unstable and reactive? Presumably ingesting highly reactive reagents is toxic.
Earlier quoted context omitted.
> That a therapeutic drug is explosive only adds to that sentiment. Explosivity and toxicity are unrelated. Cyanide can kill you, but it's not explosive IIRC. You can make explosives with aluminum, but it's safe to use as a food container, ... > Chemotherapy is basically cave man medicine. The main problem is that cancer cells and normal cells are very similar. Anything that kills cancer cells will probably kill norm…
>Explosivity and toxicity are unrelated. Really? Doesn't something being explosive mean it's highly unstable and reactive? Presumably ingesting highly reactive reagents is toxic.
Not particularly, no. Some certainly are, but others require a great deal of activation energy to detonate. Nitroglycerine (another explosive medication) is notoriously touchy. But C4 is only mildly flammable; you can heat up your meal by lighting a piece of C4 on fire then put the fire out by smashing it with a hammer; it won't detonate like that.
Chemotherapy is basically cave man medicine. That a therapeutic drug is explosive only adds to that sentiment. The idea that we'll basically poison you just up to a point that's nearly fatal in order to kill the cancer is such a terrible way to treat someone. Now I'm not saying don't ever do it -- unfortunately that's where we're at in 2021. It's just kind of unbelievable that cancer remains so elusive that we're sti…
And it’s not like our approach is all that different for other life threatening diseases. Multi-drug resistant infection? Let me use antibiotics on you that will make you deaf and maybe damage your heart.
"What they found was rapid onset of decomposition at 170 degrees" So this seems to be more about people in a lab situation rather than it being so unstable it reacting sitting in someone's hot car. Suspecting it to react at 212 and finding it reacting at 170 could ruin a lab tech's day to be sure. Those are the jobs that sound fun "for the science" lets see what happens when...
This drug is unique in that it’s highly exothermic when it decomposes at 170C, but yeah, not exactly a risky “explosive” to work with.
Earlier quoted context omitted.
>Explosivity and toxicity are unrelated. Really? Doesn't something being explosive mean it's highly unstable and reactive? Presumably ingesting highly reactive reagents is toxic.
> Really? Doesn't something being explosive mean it's highly unstable and reactive? Not particularly, no. Some certainly are, but others require a great deal of activation energy to detonate. Nitroglycerine (another explosive medication) is notoriously touchy. But C4 is only mildly flammable; you can heat up your meal by lighting a piece of C4 on fire then put the fire out by smashing it with a hammer; it won't deton…
Somewhat surprisingly, this was NOT filed under "Stuff I Won't Work With"
Maybe helpful to note that the phrase "Class 1 Explosive" isn't denoting a certain type, or power of "Explosive". "Class 1" in Hazmat is all explosives. Class 2 is Gases. Class 3 is Flammable or Combustible liquid, and so on.
Chemotherapy is basically cave man medicine. That a therapeutic drug is explosive only adds to that sentiment. The idea that we'll basically poison you just up to a point that's nearly fatal in order to kill the cancer is such a terrible way to treat someone. Now I'm not saying don't ever do it -- unfortunately that's where we're at in 2021. It's just kind of unbelievable that cancer remains so elusive that we're sti…
Earlier quoted context omitted.
Nitrogen-Nitrogen bonds inside larger molecules are never quite stable because 1) nitrogen “wants” to form stable di-nitrogen (N2) molecules containing a very stable triple bond (an exothermic reaction) and 2) the result of such decompositions is nitrogen gas increasing the amount of entropy released (due to more molecules being created). Reactions are driven both by the amount of heat released (enthalpy) and the amo…
Does the same apply to oxygen? Since it also likes to be in a diatomic form.