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Vaccine made of live malaria parasites shows early success

nature.com

1–10 of 33 posts

Re: Vaccine made of live malaria parasites shows early success

#2
This post violates the "no politics" rule of HN. ergo:

KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE!

KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE! KILL FAUCI!

SHOVE YOUR VACCINE UP YOUR ASS!

MASK FASCISTS MUST FUCKING DIE!

want more? keep posting CLEARLY political, non-hacking, non-startup bullshit - fucking fascist pieces of shit.

Re: Vaccine made of live malaria parasites shows early success

#4
> The sporozoites must be harvested from mosquito salivary glands and then stored at extremely low temperatures, complicating their distribution in resource-poor areas. No vaccine has ever been mass-produced using mosquitoes before. Alonso remembers someone asking him about the possibility years ago: “It is a crazy idea,” he replied at the time.

Crazy indeed, it’s amazing the things people think up.

Re: Vaccine made of live malaria parasites shows early success

#7
How do vaccines with live parasites work? Does attenuation somehow guarantee that the live parasites won't replicate to the point of becoming a full-on infection?

Can these vaccines only be used on patients with healthy immune systems, and those with weakened immune systems have the potential for cascading replication and full infections?

Re: Vaccine made of live malaria parasites shows early success

#8

“Participants were then intentionally infected with malaria three months later to test the vaccine’s efficacy.” I did not know that purposely infecting people with a deadly parasite for research was a thing!

It's called a challenge trial. It's done to compress later stages of clinical trials and only uses low risk volunteers. It's also generally only done when theres effective treatment for expected negative outcomes.

Re: Vaccine made of live malaria parasites shows early success

#9

“Participants were then intentionally infected with malaria three months later to test the vaccine’s efficacy.” I did not know that purposely infecting people with a deadly parasite for research was a thing!

Parasite, not a virus. For some parts of the world, it's like getting the flu. You expect to get it every year.

Re: Vaccine made of live malaria parasites shows early success

#10
Nice idea, but there's no way something like this would pass FDA. Even for the live VSV Ebola vaccine that contains no Ebola at all in it, except for the encoded spike, it's recommended for a doctor to do administration, and it's not commercially available, so you have to justify your need for it to the federal government. You are also supposed to avoid close contact with anyone else for quite a while after, to prevent transmission of the vaccine virus.

https://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/ebo...

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