>Doctors infused billions of microscopic structures known as nanoparticles carrying genetic instructions for the CRISPR gene-editor into four patients in London and two in New Zealand. The nanoparticles were absorbed by their livers, where they unleashed armies of CRISPR gene-editors. The CRISPR editor honed in on the target gene in the liver and sliced it, disabling production of the destructive protein. this is one…
If eating GMOs has you scared, this should be absolutely terrifying
Yeah I bet the dude in the article is scared shitless about nanoparticles now that he's not gonna die.
It's only a matter of time before we use this to cosmetically modify our bodies. I predict that at the very least we'll use this technic to change our hair color and eye color. I will even say skin color too, with-in the next 50 years. Most people won't use it but there will be an active market , legal or illegal, for the modifications. The Sci-Fi future is here.
Hair and eye color is bare minimum. You're gonna see cat girls and wolf boys and dragonkin and all kinds of weird ass shit. People making themselves intentionally disabled, people giving themselves a third arm, the sky's the limit!
Crazy genetics ideas I would like explored A modified tree that drops nuts of (nearly) pure graphite or some other form of nondecomposable carbon which we can easily harvest and sequester. Photosynthesis in humans to supplement our energy consumption. Shoutout to Knights of Sidonia. I understand the ethical issues surrounding the second one.
There are populated areas whose livability is threatened by climate change. These are in very poor, low-latitude regions like Northern India. Sorry to burst your bubble, but PNWers will have the privilege of surviving and thriving with relatively minimal issue. As always, the consequences of the environmental sins of the global wealthy, like you and me and most HNers, will be borne by the global poor in other places.…
I'm not sure your calm and comprehensive reckoning of your options will be comprehensive enough to have any effect on where we as a species are heading. Because I don't shy away from facts, I am paralyzed? I disagree. If anything, I am less paralyzed than people who refuse to see where this path leads. I vote for green policies and try to inform others, even when I know there is no hope.
Nah, you don't know the technology well enough to say if there is no hope. This is just the fashionable moralistic eco-despair of the privileged: "we are doomed because we deserve it." No, we're not doomed, maybe some poor people of the global South are because of what we do, but we're not.
I'm not sure your calm and comprehensive reckoning of your options will be comprehensive enough to have any effect on where we as a species are heading. Because I don't shy away from facts, I am paralyzed? I disagree. If anything, I am less paralyzed than people who refuse to see where this path leads. I vote for green policies and try to inform others, even when I know there is no hope.
Nah, you don't know the technology well enough to say if there is no hope. This is just the fashionable moralistic eco-despair of the privileged: "we are doomed because we deserve it." No, we're not doomed, maybe some poor people of the global South are because of what we do, but we're not.
The science agrees with me. What is this "the technology" that you refer to? Carbon capture?
Nah, you don't know the technology well enough to say if there is no hope. This is just the fashionable moralistic eco-despair of the privileged: "we are doomed because we deserve it." No, we're not doomed, maybe some poor people of the global South are because of what we do, but we're not.
The science agrees with me. What is this "the technology" that you refer to? Carbon capture?
"The" science, whatever that is supposed to be, doesn't say we are all doomed.
Please do familial hypercholesterolemia soon! I know it would be harder but getting started on targeting specific mutations could be fruitful. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681164/
It's coming very, very soon. Verve just IPO'ed and you check out their S1 to see their data on using the exact same idea (N1mΨ mRNA + gRNA inside LNP) to treat hypercholesterolemia! The data look amazing in non-human primates, which based on the Intellia data, suggest 10-fold lower dose in humans should work just fine. https://www.biospace.com/article/releases/verve-therapeutics...
That's amazing! How does one register as a potential patient for the trials?