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Brain imaging before and after Covid-19 in UK Biobank

medrxiv.org

111–120 of 212 posts

Re: Brain imaging before and after Covid-19 in UK Biobank

#111
post #43

Earlier quoted context omitted.

> You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? Rather than injecting yourself with mRNA which will create long-term antibodies in your organism which will be reactivated any time something like COVID19 appears again in the nature, it's probably safer to rely on COVID19 treatments are are short lived (as in, metabolized) and reduce the viral load swiftly.

mRNA is short-lived, metabolized, etc. That's exactly how Pfizer and Moderna vaccines work. > Once the instructions (mRNA) are inside the immune cells, the cells use them to make the protein piece. After the protein piece is made, the cell breaks down the instructions and gets rid of them. [0] You seem to be arguing against the principle of vaccination in general. [0] https://www.cdc.gov/coronavirus/2019-ncov/vaccine…

mRNA are short-lived but the modified spike-specific T cells T-cells they create are not.

Re: Brain imaging before and after Covid-19 in UK Biobank

#112
post #41

Earlier quoted context omitted.

Call me stupid for waiting to get vaccinated... But I'm not stupid enough to base that decision on a Twitter thread. The problem I have is that inclusive discussion is being suppressed, and I can't make a decision based on clearly biased information. ref. https://www.youtube.com/watch?v=-_NNTVJzqtY

The video you linked is removed.for violating guidelines, which I'm guessing means it had a conspiratorial slant. Discussion does not have to include unsupported or crackpot claims to be "inclusive".

[deleted]

Re: Brain imaging before and after Covid-19 in UK Biobank

#113
post #74

Earlier quoted context omitted.

yes, but by taking the vaccine 100% chance of doing that. Virus, only if I get it.

You're weighing a real possibility against an unfounded one. P(Complications|Covid) has a calculatable probability. P(Complications|Vaccine) is not, because we don't even know if they exist. And further, we strongly suspect they don't. In other words, I think you're trading one hand for (at best) one in the bush.

Two of my brothers-in-law were hospitalized after receiving the vaccine.

Re: Brain imaging before and after Covid-19 in UK Biobank

#114

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

There are valid concerns and a difficult risk benefit analysis for some cohorts, I think. What are your thoughts on this? Put yourself in her shoes: "I held off on a COVID vaccine because I wanted to wait for data with positive signals for both pregnancy in the short term and long-run fertility. I’m trying to get pregnant, and those are the two things I care about most. Vaccine data is so politicized that it’s actual…

> data is worrisome

I'd love to learn more about this but run into the walls your described about everyone dismissing your worries. Where is this data?

Re: Brain imaging before and after Covid-19 in UK Biobank

#115

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

[deleted]

Re: Brain imaging before and after Covid-19 in UK Biobank

#116
post #85

Earlier quoted context omitted.

Instead of looking up the original video (e.g. by using the watch id), you immediately write it off as "crackpot claims" because some unknown authority at YouTube removed it, citing broad community guidelines. Maybe we should stick to your words from 4 days ago: "Science reporting is terrible and the general education system doesn't teach rational skepticism, it teaches unconditional trust of intellectual authority."…

In my experience on forums, when someone makes a grand contrarian claim (“vaccines are risky”) and then cites a video without explaining why it is relevant or summing it up, the claims indeed have extremely high odds of being crackpot claims.

Where do you see the "crackpot claims" in this situation? He/she just stated that "inclusive discussion is being suppressed", showing a recently removed YT video.

For anyone who can't take 30s to look it up: It is a discussion between 3 individuals (2 of them already fully vaccinated with Moderna) regarding the pandemic:

https://www.youtube.com/watch?v=6XkRq4PaHqo

Re: Brain imaging before and after Covid-19 in UK Biobank

#117
post #67

Earlier quoted context omitted.

> until more is known about long term effects I'm curious about this line of reasoning. We've been testing mRNA treatments for other diseases for about 25 years now. The approach was abandoned for gene therapy because the effects weren't long lasting. We have follow up data on people who participated in those studies, and to my knowledge there aren't any documented negative long term effects. We know what the vaccine…

Not caution. Willingness to accept death should it come. I'm part of the natural world, and viruses are a natural way that keep population in balance. All these vaccines are keeping more kindling for a bigger fire down humanity's timeline. I would probably reconsider if the odds where much worse than 1%.

But the thing is that getting vaccinated isn't just a matter of individual safety. It's a way to minimize the spread throughout the whole of society. Even if the death rate would be only 1%, it's a whole lot of unnecessary death when dealing with a large population. Not to mention all the non-lethal yet life altering conditions that may follow full blown COVID.

Regarding your naturalistic argument, I doubt that you have the same outlook when it comes to other aspects of life. There is no shortage of natural causes of death that we try to avoid in our everyday lives. Unless you are proposing that we use COVID as an opportunity to literally and explicitly cull the human population, I don't think that reasoning holds water.

Re: Brain imaging before and after Covid-19 in UK Biobank

#118

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

There are valid concerns and a difficult risk benefit analysis for some cohorts, I think. What are your thoughts on this? Put yourself in her shoes: "I held off on a COVID vaccine because I wanted to wait for data with positive signals for both pregnancy in the short term and long-run fertility. I’m trying to get pregnant, and those are the two things I care about most. Vaccine data is so politicized that it’s actual…

You're right in a way but I think these people are still a tad wrong. It's not that everyone deny there can be side effects, on pregnancy or otherwise. It's that if nobody does the sacrifice, and everybody has his little thing he wants to protect (you want to get pregnant, I want to keep on working, my wife wants to be there for our kid, our parents have diabetes, etc etc) then nobody gets the vaccine.

Get it, whatever it cost you, because it's your duty.

Re: Brain imaging before and after Covid-19 in UK Biobank

#119
post #67

Earlier quoted context omitted.

> until more is known about long term effects I'm curious about this line of reasoning. We've been testing mRNA treatments for other diseases for about 25 years now. The approach was abandoned for gene therapy because the effects weren't long lasting. We have follow up data on people who participated in those studies, and to my knowledge there aren't any documented negative long term effects. We know what the vaccine…

Not caution. Willingness to accept death should it come. I'm part of the natural world, and viruses are a natural way that keep population in balance. All these vaccines are keeping more kindling for a bigger fire down humanity's timeline. I would probably reconsider if the odds where much worse than 1%.

This doesn't make a lot of logical sense to me.

> natural way that keep population in balance

This is essentially a faith based belief, and not something rooted in personal risk as you previously mentioned.

> All these vaccines are keeping more kindling for a bigger fire down humanity's timeline.

Viral infections don't just kill you or you'll be fine. There are expensive (to society) effects of lots of people having diminished physical and cognitive capacity after infection. More over, by not being vaccinated you are imposing extra risk on anyone you contact who is unlucky enough to be in the narrow slice of people who are vaccinated but still susceptible to infection.

I don't see how you can argue from a perspective of unknown vaccine risk and some sort of concept of needing a virus to kill "excess population." That just seems perverse to me.

Re: Brain imaging before and after Covid-19 in UK Biobank

#120

Earlier quoted context omitted.

Yeah. I had complete loss of smell and taste, which came back about 90% over the next six weeks. It was fine for a month and then it went wonky. Probably 30% of my "scent spectrum" has now been replaced with the same burnt meat smell/taste. Everything from chocolate to feces to hamburgers now has the same core odor. It really, really sucks.

Did getting vaccinated change anything ? I've heard that vaccinations helped people with long COVID. Hope you recover fully. Edit: since someone asked for citations, here is a CNN link https://us.cnn.com/2021/04/03/health/long-haulers-vaccine-we... I follow the "This week in virology" podcast and they have discussed this extensively as well. Dr Daniel Griffin, cited in the CNN article is a weekly contributor on this…

Unfortunately the vaccine helps only in about 20% of the cases.
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