Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Brain imaging before and after Covid-19 in UK Biobank

medrxiv.org

Post reply on HN
Print view View original

21–30 of 212 posts

Re: Brain imaging before and after Covid-19 in UK Biobank

#21

Post by captainredbeard »

anthomtb wrote: post #15
hallway_monitor wrote: post #6

Earlier quoted context omitted.

Agree completely. That said, ideally I don't want either. Since a lot of people wanted to get vaccinated immediately, I can avoid that and the virus with very high probability. If needed, I'll take v3 or so of the mRNA vaccine.

Most of the arguments against accepting an mRNA shot read as “too new, do not want” to me. What are the specific long-term side effects that one should be aware of when accepting an mRNA shot?

It’s more the effects of free circulating spike protein in the bloodstream than mRNA triggering ribosomes.

Re: Brain imaging before and after Covid-19 in UK Biobank

#23

Post by lrem »

hallway_monitor wrote: post #6
JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

Agree completely. That said, ideally I don't want either. Since a lot of people wanted to get vaccinated immediately, I can avoid that and the virus with very high probability. If needed, I'll take v3 or so of the mRNA vaccine.

Your very high probability rides on the virus dying down. Which will happen after enough people get vaccinated to bring Reff < 1. Which with the original variant required 50% of the population and probably only adults counted. With the newest variant, that threshold grows to about 80% and probably needs to involve children. The longer we wait, the higher the chance it will never die down.

Re: Brain imaging before and after Covid-19 in UK Biobank

#24

Post by lima »

plank_time wrote: post #12
JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

What is the percentage of people who suffered any long term brain effects? And did they do the same study against people who got the flu and other diseases?

> And did they do the same study against people who got the flu and other diseases?

Does this matter?

Re: Brain imaging before and after Covid-19 in UK Biobank

#25

Post by [deleted] »

JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

[deleted]

Re: Brain imaging before and after Covid-19 in UK Biobank

#26

Post by tux3 »

hallway_monitor wrote: post #16
egeozcan wrote: post #8

Earlier quoted context omitted.

If many people do what you are doing, some percentage can get the virus and allow it to mutate further, reducing the vaccine efficiency, putting others to risk. Prisoner's dilemma at play. meta edit: I don't like your post becoming completely gray and therefore up-voted you. It's a view that many people hold and it needs to be answered not by screaming "down-vote the selfish!" but rather with good arguments.

Oh 100%. It's a selfish play I admit. But if there's greater than zero risk of any long-term unknown effects from a vaccine, the number of people already vaccinated means the expected value is probably negative for anyone who hasn't been vaccinated yet.

Ignoring the blatant disregard for the safety of others, your calculations are off the mark.

The Delta variant is the only one you should be concerned about from here on. And a single dose of vaccine only provides minimal protection against it.

For your scheme to be safe, you would need about 80% of people around you to have 2+ doses of a high-efficacy vaccine, and ideally all with Pfizer over Astra, given their relative efficacy.

There's a greater than zero risk you're going about this wrong and will end up catching a new variant. Vaccination works, if you ACTUALLY GET THE SHOTS.

Cheers

Re: Brain imaging before and after Covid-19 in UK Biobank

#27

Post by Claudus »

JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

Maybe they are waiting for a study on “Brain imaging before and after Covid-19 Vaccination...”

Re: Brain imaging before and after Covid-19 in UK Biobank

#28

Post by causality0 »

JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

Yeah. I had complete loss of smell and taste, which came back about 90% over the next six weeks. It was fine for a month and then it went wonky. Probably 30% of my "scent spectrum" has now been replaced with the same burnt meat smell/taste. Everything from chocolate to feces to hamburgers now has the same core odor.

It really, really sucks.

Re: Brain imaging before and after Covid-19 in UK Biobank

#29

Post by ganzuul »

causality0 wrote: post #28
JohnJamesRambo wrote: post #4

I wish I could get people that are avoiding the COVID vaccine “because we don’t know what the long term effects are” to realize that we have real data showing that there are long term effects from getting full blown COVID. You don’t want a tiny piece of mRNA but you want the whole organism reproducing in your body? The whole genome and all the proteins made?

Yeah. I had complete loss of smell and taste, which came back about 90% over the next six weeks. It was fine for a month and then it went wonky. Probably 30% of my "scent spectrum" has now been replaced with the same burnt meat smell/taste. Everything from chocolate to feces to hamburgers now has the same core odor. It really, really sucks.

How old are you? Were you completely healthy before?

Re: Brain imaging before and after Covid-19 in UK Biobank

#30

Post by leot »

goodoldneon wrote: post #11
loceng wrote: post #9

Earlier quoted context omitted.

I wish I could get people that don't understand the nuances to deeply look into, study the mRNA vaccine, currently known issues including long haul COVID symptoms of people who've only had the vaccine (via the spike protein which has turned out to be cytotoxic and seems to break away causing issues), and look seriously into the Ivermectin research and its suppression; and yes, certainly I'll be downvoted because peop…

It’s hard to trust people who make a bold claim, only to back it up with “do the research”. Why don’t you link to some of these reputable Ivermectin studies?

Here: https://journals.lww.com/americantherapeutics/Abstract/9000/...
Post reply on HN