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Ivermectin for Prevention and Treatment of Covid-19 Infection
181–190 of 644 posts
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#182Earlier quoted context omitted.
>Are you claiming that some non-trivial number of patients in India were treated with this Yes, example from two states. https://indianexpress.com/article/cities/lucknow/uttar-prade... https://www.news18.com/news/india/mortality-rate-much-lower-... The testimony video in this page cites examples in many other countries https://covid19criticalcare.com/
I see no numbers on how many people were treated on either of the first two links, and certainly don't intend to comb through the dross on the third link. So do you actually have a number? It doesn't need to be exact, just a credible source on the order of magnitude will be enough. Are we talking a thousand, a million, or a billion here? To reduce R by a factor of 2 by the use of a prophylactic drug, you'd need to ha…
This is a great comment, and an example of why discussion of ivermectin should not be CENSORED but instead debated. These would be good questions to ask the creators of any videos on the topic and from what I can see, the most popular creators would probably be open to the discussion.
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#183I heard about Ivermectin for the first time this week and was shocked how much it seemed that I had stepped into conspiracy theory land. There seemed to be an overwhelming amount of evidence over the last year that this repurposed drug is effective at treating Covid during a variety of stages (preventative, first positive test, ICU admittance, and even long haul). But since there hadn't been a randomized trial the dr…
You can't get EUA for the vaccines if there's a working treatment. The doctor who promoted Hydroxychloroquine and zinc treatment, Dr. Zelenko, is still banned from Twitter for spreading COVID disinformation. There's both actual conspiracies in this world, and well poisoning to damage the conversations. When you look at the amount of money these companies stand to make from producing billions of vaccinations, you shou…
Lots of others have debunked this here. Yet with all this conspiracy stuff there’s a big elephant in the room that no one seems to ever talk about: Covid is a global virus. The FDA can block and approve whatever treatments in the US, but it has no authority in Brazil or Thailand. If all these conspiracy drugs worked well yet the FDA blocked it for some malicious intent, the rest of the world would approve and use it. Particularly since these conspiracy drugs have all been around forever, are generics, and exist globally. Yet we aren’t seeing this emerging despite massive world wide deaths.
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#184Earlier quoted context omitted.
Please don't post flamebait to HN, and especially not on divisive topics. That amounts to trolling, in effect if not in intention, and it leads to exactly the opposite of what we're trying for here. https://news.ycombinator.com/newsguidelines.html Edit: you posted this right after I asked you to stop doing it ( https://news.ycombinator.com/item?id=27563671 ). If you pull a trick like that again, we will ban you.
Citing Roman et al. > Conclusions: In comparison to SOC or placebo, IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease. IVM did not have effect on AEs or SAEs. IVM is not a viable option to treat COVID-19 patients. [1] [1] https://www.medrxiv.org/content/10.1101/2021.05.21.21257595v... I would prefer to see a single RCT with at least a few t…
I have seen people pointing out the low price of the horse formulations on Twitter without the obvious caveat that dosage will definitely make the poison in this case.
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#185The antiparasitic ivermectin, with antiviral and anti-inflammatory properties That makes me wonder at the mechanism and biological pathways involved in how this works at all on anything and how that intersects with Covid-19. I'm alive in part because for some years my best friend was a former registered nurse who had let her nursing license lapse while she raised her special-needs sons and pursued training in various…
Some drugs are developed with a particular mechanism in mind: a known protein target, a known binding site, and a molecule designed to match. For these, scientists have a good shot at knowing what's going on. Even then, a doctor might not know - they don't need to.
Other drugs are developed by a more random method - for example, take every druglike chemical you have on the shelf and put it in a vial with COVID-19. In that case, scientists will try to find the mechanism afterwards, but they might never know for sure.
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#186Who are the scientists that instructed YouTube to take down the "Bret Weinstein and Pierre Kory" video?
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#187Earlier quoted context omitted.
Please don't post flamebait to HN, and especially not on divisive topics. That amounts to trolling, in effect if not in intention, and it leads to exactly the opposite of what we're trying for here. https://news.ycombinator.com/newsguidelines.html Edit: you posted this right after I asked you to stop doing it ( https://news.ycombinator.com/item?id=27563671 ). If you pull a trick like that again, we will ban you.
Citing Roman et al. > Conclusions: In comparison to SOC or placebo, IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease. IVM did not have effect on AEs or SAEs. IVM is not a viable option to treat COVID-19 patients. [1] [1] https://www.medrxiv.org/content/10.1101/2021.05.21.21257595v... I would prefer to see a single RCT with at least a few t…
This is one of those cases where it's helpful, in fact indispensable, to remember that there is exactly one thing we're optimizing for on HN, namely intellectual curiosity: https://hn.algolia.com/?dateRange=all&page=0&prefix=true&sor.... The fact that we have a clear guiding principle is my favorite thing about moderating HN because how the hell would one decide these things otherwise.
It seems clear that the community has genuine intellectual curiosity in discussing this topic. It's also a flamewar topic so we need to take the usual care not to end up in a flamewar; that sometimes works and sometimes doesn't. This thread doesn't seem to be doing too badly. The OP seems like a substantive enough article to at least provide a basis for a good discussion.
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#188Also, and feel free to downvote... > multiple authoritative sources Gross! Authority is the problem. We need to use our own minds. The very idea that an ad tech co is backing an amorphous group of authoritative governmental bodies is repugnant. > And here is Merck, that sells Ivermectin Ivermectin has been out of patent for years--so it is not particularly profitable anyway. The initial claim insinuates that Merck we…
> Authority is the problem. We need to use our own minds.
No offense, but that depends on the quality of minds. What you've just said is exactly what Q-Anon proponents say, just before they go on to repeat absolutely baseless conspiracy theories they heard about on YouTube.
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#189Earlier quoted context omitted.
The vaccine is experimental and the full safety profile is still being discovered. The EUA specially requires that there is "no adequate, approved, and available alternatives". The conclusion: "large reductions in COVID-19 deaths are possible using ivermectin" suggests it may be a viable alternative to widescale deployment of a vaccine that did not go through the full approval process.
No, sorry. The linked study suggests a 60% reduction in deaths from this drug. Even if it were true, it is nowhere enough to be an adequeate alternative to the vaccines, that were both vastly more effective at reducing deaths and could also significantly reduce transmission.
If you got the first dose of vaccine and then presented with COVID (that does happen), a short course of ivermectin immediately could likely do you some real good.
Re: Ivermectin for Prevention and Treatment of Covid-19 Infection
#190N=1. Me and my 2 year old had covid. My wife started ivermectin and never got sick. Shared bed and sick 2 year old wants mommy. Ivermectin didn't work for me (diarrhea) but my fever went from 102.7 down to 99 12 hours after HQC after 6 days of a slow downward spiral (fever kept going up and up every day). So for me, my take is the drugs absolutely worked.
this is not how science works
But it is how science starts.