This is true for _libpython_ (the shared library version), which is the default on some distros (RedHat, Fedora, Arch), but many others (Debian, Ubuntu) use statically linked Python and never paid this performance tax.
So what do Redhat, Fedora, Arch gain by using the shared libpython? Who except python is using the library?
For example Vim (if so configured), or Postgres PL/Python, or the old Apache mod_python.