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It'd be nice if they mentioned how many cases there were, compared to number of shots.
That should be second-paragraph-of-article sorts of information.
Anecdote: I had this reaction to the 2nd dose of the Pfizer vaccine, saw a cardiologist and she mentioned that she’s been seeing this quite a bit after the second dose. Have had to lay low for a month, but it seems like the symptoms are finally passing.
It'd be nice if they mentioned how many cases there were, compared to number of shots.
488 total reports from Pfizer-BioNTech, 301 reports from Moderna.
Slide 18 shows proportions. 12,169,692 doses administered. Expected number (base rate) of Myocarditis/pericarditis cases in persons under 25, 10 to 103. Cases observed: 277. So it roughly quadrupled the base rate. Which brings the adverse reaction rate up to... 0.000276%
Anecdote: I had this reaction to the 2nd dose of the Pfizer vaccine, saw a cardiologist and she mentioned that she’s been seeing this quite a bit after the second dose. Have had to lay low for a month, but it seems like the symptoms are finally passing.
It'd be nice if they mentioned how many cases there were, compared to number of shots.
> "There were 283 observed cases of heart inflammation after the second vaccine dose in those aged 16 to 24 in the VAERS data. That compares with expectations of 10-to-102 cases for that age range based on U.S. population background incidence rates, the CDC said."
They use Observed vs. Expected cases in order to calculate e.g. a reporting odds ratio [2], which can loosely guide you in finding events which occur disproportionately.
1. https://en.wikipedia.org/wiki/Postmarketing_surveillance
2. https://allaboutpharmacovigilance.org/43-reporting-odds-rati...
Can the government present anything in a useful manner? The most important information, i.e. if the young men engaged in heavy sports right after getting the vaccine, is missing. Heavy sports is obviously also dangerous while recovering from the flu. But the disorganized chaotic government presentation doesn't give any useful information.
It would be irresponsible to report that as the headline because this is still a developing topic. What's important is that the FDA was watching it closely enough to detect the effect, and are following up on it.
Good job FDA. That's the kind of thing I want my taxes spent on.
It'd be nice if they mentioned how many cases there were, compared to number of shots.
They do, in this exact article. 283 cases were noted in the VAERS database, there are about 130 million fully vaccinated people in the US. I assume they don't track healthy people in the database of adverse vaccination reactions.
Anecdote: I had this reaction to the 2nd dose of the Pfizer vaccine, saw a cardiologist and she mentioned that she’s been seeing this quite a bit after the second dose. Have had to lay low for a month, but it seems like the symptoms are finally passing.
I had this after COVID in April last year right at the beginning. I suspect it is an immune reaction to the virus not the vaccine itself.
It'd be nice if they mentioned how many cases there were, compared to number of shots.
Agreed. Context matters here. I'd hate for this to get blown out of proportion like the blood clot issue did, causing massive confidence declines in places all over, especially those struggling to roll out vaccines and keep their COVID cases under control. Obviously, if the numbers are alarming, we must react accordingly.
Observed (O) cases in that age group: 283
Expected (E) cases in that age group: 10-102
So at least double the top of the confidence interval, for expected.
The interesting table with absolute numbers is on page 18 of [0]. Expected and observed cases are cases of myocarditis / pericarditis here. Crude rate is the number of cases per 1 million administered doses. Use landscape mode if you are reading this from a mobile device, the table is narrow enough for that. Age group Doses Crude Expected Observed administ. rate cases cases 12–15 yrs 134,041 22.4 0–1 2 16–17 yrs 2,25…
So a lot more incidents than expected, but still extremely rare (0.002% of doses).
Edit: missed an extra "0" in that percent, thanks for the the catch everyone who did