Any other result would have been surprising. Why is this interesting, beyond just confirming what we were already 99.99% certain we knew? -- biochemist
It's consistent with the past years saturated reporting of the obvious about infectious diseases.
Evaluating necessity of Covid-19 vaccination in previously infected individuals
91–100 of 361 posts
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#92Earlier quoted context omitted.
This is a dubious claim, and is a frequent anti-vaxx/vaccine-hesitancy talking point. VAERS data needs to be interpreted with special care. It's not equivalent to a safety study with a proper experimental design. It has a whole lot of legal and administrative context to account for.
And until the studies happen there is no danger? The studies create the danger? Or may we behave like rational individuals and realize that "zero danger" is a political talking point which is fully debunked by the VAERS data?
You need to apply some Bayesian thinking. No reasonable person (expert or not) believes in such a thing as zero danger.
- The vast majority of new drugs that undergo safety trials are found to have serious side effects.
- The near totality of new vaccines that undergo safety trials are found to have a formidably beneficial risk profile.
Don't make the mistake of applying the same risk heuristic in your mind for both things. Risk assessments in science have absolutely nothing to do with politics.
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#93Punchline: “The cumulative incidence of SARS-CoV-2 infection remained almost zero among previously infected unvaccinated subjects, previously infected subjects who were vaccinated, and previously uninfected subjects who were vaccinated, compared with a steady increase in cumulative incidence among previously uninfected subjects who remained unvaccinated. Not one of the 1359 previously infected subjects who remained u…
A couple recent studies indicate that previously infected and then vaccinated individuals may have longer term immunity than those who are vaccinated but weren't previously infected or those who were infected but haven't been vaccinated:
> Immunity to the coronavirus lasts at least a year, possibly a lifetime, improving over time especially after vaccination, according to two new studies. The findings may help put to rest lingering fears that protection against the virus will be short-lived.
> Together, the studies suggest that most people who have recovered from Covid-19 and who were later immunized will not need boosters. Vaccinated people who were never infected most likely will need the shots, however, as will a minority who were infected but did not produce a robust immune response. Both reports looked at people who had been exposed to the coronavirus about a year earlier. Cells that retain a memory of the virus persist in the bone marrow and may churn out antibodies whenever needed, according to one of the studies, published on Monday in the journal Nature. The other study, posted online at BioRxiv, a site for biology research, found that these so-called memory B cells continue to mature and strengthen for at least 12 months after the initial infection.
> “The papers are consistent with the growing body of literature that suggests that immunity elicited by infection and vaccination for SARS-CoV-2 appears to be long-lived,” said Scott Hensley, an immunologist at the University of Pennsylvania who was not involved in the research.
https://www.nytimes.com/2021/05/26/health/coronavirus-immuni...
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#94Earlier quoted context omitted.
Yeah, in theory that would be the obvious advantage. In practice, don't underestimate how much more inefficient or troublesome a seemingly simple additional rule or exception might be to administer... :P
That's my thing. Plenty of people who know they almost certainly had Covid weren't tested, some were tested with tests that were experimental, etc. And while trying to predict second-order behavior effects is tricky either way it is pretty clear that saying "don't get the vaccine if you already had Covid" would scare some people away.
Bingo.
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#95Any other result would have been surprising. Why is this interesting, beyond just confirming what we were already 99.99% certain we knew? -- biochemist
Further evidence is further evidence, no? You have to measure and assess to get results...
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#96Any other result would have been surprising. Why is this interesting, beyond just confirming what we were already 99.99% certain we knew? -- biochemist
Most authorities are downplaying natural immunity, despite evidence like this. The more widely this spreads, the more people will realize it's ok to rely on natural immunity, and to not blanket demonize those who are unvaccinated.
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#97Earlier quoted context omitted.
That's encouraging! I got COVID a few months ago and got vaccinated recently, seems like I should be unstoppable now.
Hey I'm curious, if you don't mind sharing, how do you think you got it? Throughout this whole pandemic, I'm still kind of amazed how people are getting it
Went to visit my parents and my dad thought it prudent to have a 60 minute meeting with a stranger in an unventilated office at work. Yaaaaay...
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#98Earlier quoted context omitted.
Hey I'm curious, if you don't mind sharing, how do you think you got it? Throughout this whole pandemic, I'm still kind of amazed how people are getting it
Given that it’s airborne chances are through breathing in proximity with someone who is currently contagious (and possibly asymptomatic). Non-huge indoor spaces, absence of masks, breathing the same air for longer than 15-20 min all increase infection rates. Not OP.
It's even worse than that, my dad got it in an indoor space (office) while both he and the carrier were wearing masks. Then I got it from him in the house, even though I avoided him and kept my distance.
He wouldn't wear a mask in the house (because "I'm fine") and kept coughing up the place, though.
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#99Earlier quoted context omitted.
Because it's not public health policy anywhere that I'm aware of? But vaccine rollout would be way quicker, and 'positive test or vaccinated' proportion of populations would be way higher, and that would influence discussion of other aspects, like 'herd immunity' for example.
My one anti-vax friend (who I make fun of constantly for not getting it) is constantly bombarded with people telling him that his previous infection doesn't give him any immunity. I already knew that was false - and I think he knew that too. It probably fed into his (motivated) reasoning to hold out this long if people are telling him so much information they know to be untrue. Still, I don't see how public health wo…
It's certainly arguable that there is downside for some people. Some vaccine side effects are worse for some people who have already been infected. [1]
[1] https://www.kfyrtv.com/2021/03/15/health-experts-say-those-p...
Re: Evaluating necessity of Covid-19 vaccination in previously infected individuals
#100Punchline: “The cumulative incidence of SARS-CoV-2 infection remained almost zero among previously infected unvaccinated subjects, previously infected subjects who were vaccinated, and previously uninfected subjects who were vaccinated, compared with a steady increase in cumulative incidence among previously uninfected subjects who remained unvaccinated. Not one of the 1359 previously infected subjects who remained u…
I don’t see it in the abstract, but what was the infection rate for the unvaccinated? That’s your comparison.
They also mentioned 0 infections in fully vaccinated which is odd as other countries are seeing a number of infections in their vaccinated front line workers.
https://twitter.com/sporeMOH/status/1402637555263098884?s=20