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Drug users use a lot of drugs

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Re: Drug users use a lot of drugs

#31

"The most important reason meth makes your teeth fall out and ruins your life but Adderall just makes you study a little harder is that the meth users are taking 50x higher doses" The reason meth addicts have bad teeth isn't because of the dosage of the drug. It's because stimulants make you want to eat candy and drink sugar water, because meth addicts lose track of oral hygiene in favor of doing meth or something el…

This isn’t correct. Meth, when smoked, is incredibly toxic. The toxic smoke that causes “meth mouth”

Re: Drug users use a lot of drugs

#32
Former meth addict here.

> The average crystal meth addict uses about 500 mg a day. And they snort it, which probably produces about double the peak plasma level as taking it orally. So they're getting the equivalent of 1000 mg oral amphetamine daily...

500mg sounds about right, but from my experience the most common route of administration (in the western United States at least) is smoking, not snorting.

Because so many people smoke meth rather than snort it, a lot of meth is sold as methamphetamine base rather than methamphetamine hydrochloride.

This means that it’s often not particularly water soluble, which makes it a poor choice for snorting since it doesn’t get through your nasal mucosa and actually kicks in after it drips down into your stomach. It’s not actually much different from eating it in many cases.

I like this article overall but I get irritated when I read stuff about drug users that is clearly written by somebody who hasn’t done a lot of drugs.

Edited for spelling. Also if anybody has any questions for me, I’m pretty knowledgeable on this topic (though no expert), so feel free to ask away!

Re: Drug users use a lot of drugs

#33
post #23

Earlier quoted context omitted.

His teeth are far more likely to be falling out because of bad oral hygiene for a decade earlier in life than they are because of a low dose of Adderal or anything. If 120mg of Adderal made your teeth fall out then tons more people would have their teeth falling out.

To be clear, 120mg is what he takes first thing in the morning. He takes more throughout the day. I’d guess he takes 500+ in a day.

That is impossible. There is no one someone's heart would be able to take that. I take 60 mg daily of Vyvanse and I'm pretty wired all day. I can't even fathom the effects of that on a human body.

Is he like 300 lbs?

Re: Drug users use a lot of drugs

#34

It's hard to read Scott once you hear about how he courted the alt-right on purpose and his communities became full of open racists as a result.

It shouldn't be hard for a grownup to read his texts even if that were true.

And that's "Mr. Alexander" to you, GP.

Re: Drug users use a lot of drugs

#35
This article isn't bad, but it's a very shallow, narrow view of things.

In general it seems to make no distinction with addicts using high doses to overcome tolerance levels with recreational drug users in general.

Methamphetamines and amphetamines are not the same chemical, despite being similar.

https://methoide.fcm.arizona.edu/infocenter/index.cfm?stid=1...

The small differences between the molecules allow it to penetrate the blood brain barrier more efficiently, has longer lasting toxic effects and acts more as a central nervous system stimulant and

>less peripheral nervous system and cardiovascular stimulation activity. Another difference between amphetamine and MA is that amphetamine stimulates the CNS indirectly by activating the release of catecholamines and inhibiting their breakdown and storage. In contrast, MA stimulates the postsynaptic catecholamine receptors directly.[2]

Increased dosage is only one part of the difference between Methamphetamine and Amphetamines. Street meth is also far more likely to have fillers, leftover solvents and a bunch of other things that are not good for you.

>In general, recreational drug users take their drugs at doses so much higher than psychiatric patients that they're basically two different chemicals

Recreational drug users come in a wide range. The first two sections of the article speak about addicts doing extremely large doses, then seems to lump 'recreational drug users' altogether with that.

Re: Drug users use a lot of drugs

#36
post #29

Earlier quoted context omitted.

His teeth are far more likely to be falling out because of bad oral hygiene for a decade earlier in life than they are because of a low dose of Adderal or anything. If 120mg of Adderal made your teeth fall out then tons more people would have their teeth falling out.

Are there "tons of people" seriously taking 120mg of adderall?

No, that is far beyond the daily dosage threshold.

Even 90 is extremely high for XR, and would probably be broken into 2 45 doses throughout the day.

Re: Drug users use a lot of drugs

#37
There's recreational drug users, and then there's recreational drug users. Turns out some people I know who microdosed amphetamine took doses exactly in the ballpark of what doctor would prescribe them.

Re: Drug users use a lot of drugs

#38

It's hard to read Scott once you hear about how he courted the alt-right on purpose and his communities became full of open racists as a result.

I've read a lot of his stuff and have never heard about that. Would you want to provide a link that supports your claim, so I can make an informed decision about continuing to read his generally good, substantive, and interesting content?

Re: Drug users use a lot of drugs

#39

"The most important reason meth makes your teeth fall out and ruins your life but Adderall just makes you study a little harder is that the meth users are taking 50x higher doses" The reason meth addicts have bad teeth isn't because of the dosage of the drug. It's because stimulants make you want to eat candy and drink sugar water, because meth addicts lose track of oral hygiene in favor of doing meth or something el…

Meth does not make you crave any type of food. If that were the case Desoxyn would not be FDA approved for weight loss.

“Meth mouth” is caused by the fact that it dries your mouth out, you grind your teeth a LOT, and is often observed in people that have used drugs long/hard enough to find themselves no longer taking care of their health in general, let alone oral hygiene. This often is coupled with financial ruin and utter alienation from society. Somehow, mysteriously, all of the rich house wives and Silicon Valley coders that use it develop meth mouth at a lower rate.

Re: Drug users use a lot of drugs

#40
post #9

"The most important reason meth makes your teeth fall out and ruins your life but Adderall just makes you study a little harder is that the meth users are taking 50x higher doses" The reason meth addicts have bad teeth isn't because of the dosage of the drug. It's because stimulants make you want to eat candy and drink sugar water, because meth addicts lose track of oral hygiene in favor of doing meth or something el…

Adderall is also a stimulant(?) The authors suggestion is it would cause the same effect if taken in the same dosage.

I was on Adderall 10mg a day. Worked as advertised. ADHD under control. Chronic fatigue fixed.

Every portion of my body felt like it was being burned from the inside. I had to start tramadol to counter act the pain.

It also upped cranial pressure. Causing a lot of secondary problems.

This was made much worse as dosage went up.

I had to stop it before downward spiral completely destroyed me.

Vyvanse was a mild version of all this.

Can’t imagine anything more intense.

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