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Trials begin on lozenge that rebuilds tooth enamel

dental.washington.edu

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Re: Trials begin on lozenge that rebuilds tooth enamel

#341

Post by hvidgaard »

klipt wrote: post #317
Godel_unicode wrote: post #202

Earlier quoted context omitted.

> The more you regulate your internal acidity, the more your body will try to find balance... You seem to be full of bad unsubstantiated health advice, for some reason. This is, of course, not true.

There is absolutely a rebound effect where suppressing acid production in the stomach over time causes more acid to be produced: https://www.npr.org/templates/story/story.php?storyId=112564... > Stomach cells that make acid multiply over several weeks of exposure to a PPI in an effort to overcome the drug's effect. When the PPI is stopped, they pour out more acid than ever.

And luckily stepping down reverses the production to "normal" level. PPIs are so potent that you can basically stop the acid production, which is not what you want except for a short period of time.

Re: Trials begin on lozenge that rebuilds tooth enamel

#342

Post by krageon »

nickpp wrote: post #340
jb775 wrote: post #311

Earlier quoted context omitted.

This is absolutely wrong. Especially when the formulation of the idea depends on extremely advanced knowledge of the topic.

Prove me wrong. Try selling an idea and let us know how much money you got for it.

You are making an extraordinary claim here (that an idea founded on a significant amount of study and prior experimentation is worthless). It seems to me that it's a little strange to ask someone else to disprove you when you haven't really made your own point of view plausible.

Re: Trials begin on lozenge that rebuilds tooth enamel

#343

Post by Cthulhu_ »

Wistar wrote: post #92
Hamuko wrote: post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Although I haven't personally tried it, I have friends outside of the US that rave about Sensodyne Repair & Protect original with the "Powered by NovaMin" badging. NovaMin is composed of special ceramic particles that coat the teeth with a compound that reacts with the saliva to form a durable physical barrier. The problem is that the stuff with NovaMin is not typically available in the US. I just searched Amazon and…

There was an article on HN a few weeks ago that did a deep dive into Novamin and the like, I think it was https://medium.com/@ravenstine/the-curious-history-of-novami...

Re: Trials begin on lozenge that rebuilds tooth enamel

#344

Post by nickpp »

krageon wrote: post #342
nickpp wrote: post #340

Earlier quoted context omitted.

Prove me wrong. Try selling an idea and let us know how much money you got for it.

You are making an extraordinary claim here (that an idea founded on a significant amount of study and prior experimentation is worthless). It seems to me that it's a little strange to ask someone else to disprove you when you haven't really made your own point of view plausible.

Do I really need to prove that you can starve with a million ideas in your head? That everyone around has countless ideas and it's impossible to know which ones can create value without spending time and money to try to develop them?

I think the extraordinary claim is to pretend to know the value of an idea upfront. Very few people (Venture Capitalists, business investors, etc) try that and they fail more often than they succeed.

Show me someone who can reliably predict the idea success rate and I will show you a billionaire!

Re: Trials begin on lozenge that rebuilds tooth enamel

#345

Post by ricardobeat »

abandonliberty wrote: post #334
analyte123 wrote: post #211

Earlier quoted context omitted.

Biomin also claims that their particles are smaller and therefore more effective at mineralization than Novamin. Another option for leveling up on toothpaste is using those that contain micronized hydroxyapatite. Options here are Carifree or the Japanese brand Apagard available on eBay or Amazon. Biomin’s formula is proprietary but it might contain hydroxyapatite in part. I stopped randomly getting cavities after usi…

HAP, available in Japan since 1970. wow, just found this where they compared HAP to fluoride and found no difference: https://www.nature.com/articles/s41405-019-0026-8 I have novamin. I think it makes my teeth feel different. May be placebo. A lot of people swear by HAP, novamin, etc. I suspect it all comes down to increased oral care and diligence though!

> I think it makes my teeth feel different.

I definitely feel something too, like the surface is slicker.

Re: Trials begin on lozenge that rebuilds tooth enamel

#346

Post by batter »

refurb wrote: post #160
batter wrote: post #126

Believe me or not but if you have tooth sensitivity i would check sodium balance. Especially if you urinate frequently. This can ruin your teeth for long time. Yoga wheel for upper back can help.

Your body maintains your sodium levels in a very tight band. Why? Your nerves won’t function otherwise. If it gets outside that range you typically die. So I’ll have to say I’m highly skeptical about “checking your sodium balance”.

From this study: https://www.health.harvard.edu/blog/good-heart-keep-holding-... we can see that low sodium impacts heart desease, even though your body controls it in tight range. I do agree that most probably your sodium level in blood will be in tight range. But I'm other places like saliva it could be deficient. Saliva PH strips would be a good start

Re: Trials begin on lozenge that rebuilds tooth enamel

#347

Post by krageon »

nickpp wrote: post #344
krageon wrote: post #342

Earlier quoted context omitted.

You are making an extraordinary claim here (that an idea founded on a significant amount of study and prior experimentation is worthless). It seems to me that it's a little strange to ask someone else to disprove you when you haven't really made your own point of view plausible.

Do I really need to prove that you can starve with a million ideas in your head? That everyone around has countless ideas and it's impossible to know which ones can create value without spending time and money to try to develop them? I think the extraordinary claim is to pretend to know the value of an idea upfront. Very few people (Venture Capitalists, business investors, etc) try that and they fail more often than…

You're arguing a different point than everyone else, so it makes sense that things don't make sense to you.

Re: Trials begin on lozenge that rebuilds tooth enamel

#348

Post by mancerayder »

elliekelly wrote: post #80
Hamuko wrote: post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Have you looked into botox shots at all? When I tell you my life changed completely from a 15 minute botox appointment with an oral surgeon I am not exaggerating in the least. I’d had no idea what it felt like to live without bruxism - not only were my teeth better but my neck stopped aching, my back muscles stopped spasming, and I stopped getting migraines entirely. I had gotten debilitating migraines once every mon…

I'm curious about the neck piece of it. I grind at night, too, but I have neck and upper back issues despite everything I do to prevent, including years of PT exercises.

Re: Trials begin on lozenge that rebuilds tooth enamel

#349

Post by caturopath »

xxpor wrote: post #68
jcrben wrote: post #66

Weird teeth-cleaning trick that I discovered from suffering from interstitial cystitis / painful bladder syndrome (IC / BPS): toss a bit of baking soda in your water, such as 1 teaspoon per liter. It makes it alkaline. My teeth got whiter and felt better (less of a film feeling). Baking soda is used as a cooking ingredient and shouldn't be too risky, but don't go overboard... bit of discussion on the IC / BPS aspect…

Isn't baking soda a fairly common ingredient in toothpaste? (See arm and hammer brand toothpaste)

Yes, very much so -- "natural" types have been known to recommend just using baking soda instead of toothpaste.

FWIW, brushing is the more important part (even without paste it probably does most of the good), but modern toothpastes are better than baking soda because they are more abrasive and because they contain fluoride. Baking soda's main utility for toothbrushing is its abrasiveness, but it's a little too soft to be optimal.

To get the most out of your toothpaste's fluoride, spit out your toothpaste and do not immediately rinse. You don't want to swallow large amounts of toothpaste, of course, but the film does more good than harm -- https://www.nhs.uk/live-well/healthy-body/how-to-keep-your-t... "Don't rinse your mouth immediately after brushing, as it'll wash away the concentrated fluoride in the remaining toothpaste."

Re: Trials begin on lozenge that rebuilds tooth enamel

#350

Post by mancerayder »

robocat wrote: post #36
Hamuko wrote: post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

For anybody that grinds their teeth, investigate getting a splint before you reach this stage. https://www.coredental.com.au/splints-dentist-recommend-one/

That's not for everyone. I tried it for many months, and it made my condition worse and worse. Expensive appliance molded by my dentist, he even re molded when I complained it rocked a little, and then again gave me a different tech.

All for nothing. Splint, or mouth guard in North America, caused me to develop daytime bruxism and it moved my teeth in such a way that my back teeth didn't touch firmly, which my brain wanted to resolve by biting harder.

If it's my enamel or my TMJ, I guess I picked my TMJ. Grinding with the splint made my jaw hurt more.

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