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Trials begin on lozenge that rebuilds tooth enamel

dental.washington.edu

231–240 of 364 posts

Re: Trials begin on lozenge that rebuilds tooth enamel

#231

Earlier quoted context omitted.

Well, we are talking about a possibly multi-million dollar product here. If Amazon were a bit less predatory perhaps keep 99% of the IP?

Amazon is a modern day Dutch East India Company. There’s no reason for them not to be predatory, given that they wield so much power.

Or British East India Company. Not like either wasn't predatory back in its heyday.

Re: Trials begin on lozenge that rebuilds tooth enamel

#232

Earlier quoted context omitted.

I was very surprised when I went to a dentist in Europe to fill a cavity: they don’t freeze anything by default unless you really want. I thought I’d try without anesthesia and it turned out surprisingly bearable. Plus I didn’t have half my face frozen for half a day.

As a european who got dental care in two countries: I never heard of freezing at the dentist! What do they freeze exactly? How does it relate to anestesia? Medical care seems to have a lot of weird country-specific traditions, e.g. in Hungary it's apparently common to fill small kids' healthy teeth if the groves are too deep so they're simpler to clean and they don't get cavities. I had never heard of such a thing be…

They inject something in the gums that removes sensitivity there so you feel nothing, and then have half your face frozen for 4h afterwards because it acts on the nearby nerves that control your facial muscles.

Having experienced both (frozen and not frozen), I can't tell what's better. The feeling when they're digging in the tooth without freezing isn't great but it's not painful either; the feeling when they put a needle in your gum to inject the product isn't great either but then you don't feel the procedure. I'd say it's different but equivalent in terms of discomfort.

Re: Trials begin on lozenge that rebuilds tooth enamel

#233
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Have you looked into botox shots at all? When I tell you my life changed completely from a 15 minute botox appointment with an oral surgeon I am not exaggerating in the least. I’d had no idea what it felt like to live without bruxism - not only were my teeth better but my neck stopped aching, my back muscles stopped spasming, and I stopped getting migraines entirely. I had gotten debilitating migraines once every mon…

Thanks, I’m going to try this. Wonder if it’s the cause of my neck issues.

Re: Trials begin on lozenge that rebuilds tooth enamel

#234
post #92
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Although I haven't personally tried it, I have friends outside of the US that rave about Sensodyne Repair & Protect original with the "Powered by NovaMin" badging. NovaMin is composed of special ceramic particles that coat the teeth with a compound that reacts with the saliva to form a durable physical barrier. The problem is that the stuff with NovaMin is not typically available in the US. I just searched Amazon and…

Just out of interest, and not detracting from what you're saying, but normal fluoride also forms a compound (flouro-apetite) more resistant to avoid than normal tooth material (appetite). At least according to this chemist: https://youtu.be/vtWp45Eewtw

(tooth chat at 5:10, but the whole video is interesting)

Re: Trials begin on lozenge that rebuilds tooth enamel

#235
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Have you looked into botox shots at all? When I tell you my life changed completely from a 15 minute botox appointment with an oral surgeon I am not exaggerating in the least. I’d had no idea what it felt like to live without bruxism - not only were my teeth better but my neck stopped aching, my back muscles stopped spasming, and I stopped getting migraines entirely. I had gotten debilitating migraines once every mon…

Back problems, bruxism, migraines - have you had yourself tested for some bacterial infection like e.g. lyme or bartonella? Just to have that excluded before treating symptoms.

I've had all of this for years (more like decades) plus different additional symptoms and got diagnosed last year. The ongoing treatment is not for the faint of heart but symptoms are on the retreat since.

PS: I've grown up in rural Germany and also had close contact to cattle as a kid etc.

Re: Trials begin on lozenge that rebuilds tooth enamel

#236
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Have you tried Novamin containing toothpaste (Sensodyne repair & protect) ? I've heard its not available in the US but I suppose you could still buy it online.

I've had tooth sensitivity for a while, and this tootpaste fixed the problem for me

Re: Trials begin on lozenge that rebuilds tooth enamel

#237
post #236
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Have you tried Novamin containing toothpaste (Sensodyne repair & protect) ? I've heard its not available in the US but I suppose you could still buy it online. I've had tooth sensitivity for a while, and this tootpaste fixed the problem for me

Can vouch for this toothpaste. 2-3x more expensive than regular, but I never suffer from sensitive teeth anymore.

Re: Trials begin on lozenge that rebuilds tooth enamel

#238

Earlier quoted context omitted.

Hair is a bigger market. Not in terms of people it affects, but what people will pay. But.... likewise, it amazes me we have a million and a half ways to grow hair on mice, but none on humans. Makes me think we need to relax human trials on volunteers (only half joking).

It’s really astonishing how I know, intuitively, this is true but how weird people’s priorities are. Being honest: 1. I started balding at a relatively normal age (first signs late 20s). At first I welcomed it, then I got a little self conscious (and wished for greys instead, those are finally coming into my beard and I couldn’t be happier). 2. I’ve had dental health issues since childhood. My family couldn’t afford…

I had a patient who was GOING BLIND and had a chance to get in a vision trial or a hair transplant trial but couldn't do both. He chose the hair trial. Over his own sight!!

I was really annoyed at him for a while because I had moved heaven and earth for him to help him screen into the highly competitive vision trial. But... his life, his choice. Even though he made a dumb one, imo.

Re: Trials begin on lozenge that rebuilds tooth enamel

#239
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Yeah it's necessary to visit a dentist regularly, even if you go for conservative treatments. Every now and then they might have a good recommendation. Regarding the muscle tension itself Progressive muscle relaxation can help.

Re: Trials begin on lozenge that rebuilds tooth enamel

#240
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Yeah my teeth are sensitive (cold and sugar). I could use something like this pretty badly. I've always brushed religiously but I still know over time and as you age enamel is just thinning.
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