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Trials begin on lozenge that rebuilds tooth enamel

dental.washington.edu

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Re: Trials begin on lozenge that rebuilds tooth enamel

#181
post #142

Earlier quoted context omitted.

If you switched from drip, the caffeine is actually lower! My guess is you’re just more satisfied with the coffee you’re enjoying.

Definitely enjoy it more. Brewed coffee started tasting like stewed coffee or something, the americanos just have a 'cleaner' hit...i don't know. The weird thing is I find pourover to be more like espresso than brewed in that way, so it's probably just all in my head lol. Anyway, point is I only drink one cup a day now and have become a closet coffee snob.

Pourover is more like espresso too. Almost the same mechanism, but espresso also uses pressure. And even though snobs will disagree, french press will be closer in flavor but “muddier”. Drip is pretty much the worst because it starts reheating your already perfectly good coffee before it’s even done.

Welcome to the snobbery! I went from “I refuse to order a coffee with more than two words” to super opinionated and picky, and now my rules are just don’t be insufferable and accept when my preferences aren’t reasonably available.

Re: Trials begin on lozenge that rebuilds tooth enamel

#182
post #150

Earlier quoted context omitted.

True, the darker the roast (ie roasted longer), generally the less caffeine it has in it. Espresso has some of the least since it is one of the darkest roasts.

That is an urban myth unfortunately, darker coffee does not have less caffeine because caffeine is heat stable at typical roasting temperatures. (20 to 240C). Here’s a more thorough explanation of it: https://www.kickinghorsecoffee.com/caffeine-myths-dark-vs-li... The effect probably came to be known because darker roaster coffee is less dense. So if you are measuring your coffee by volume (i.e. eyeballing it) and no…

Yeah it’s not the roast, it’s the brewing/extraction method. Drip/pour over extract more caffeine than espresso, presumably from longer exposure to more surface area.

Re: Trials begin on lozenge that rebuilds tooth enamel

#183

Earlier quoted context omitted.

Urine alkalinization will also slow down your kidney's excretion of alkaline drugs and their metabolites. And speed up excretion of acidic drugs. https://tmedweb.tulane.edu/pharmwiki/doku.php/ph_effect_on_d... And yes, you definitely don't want to overdo it: https://en.wikipedia.org/wiki/Milk-alkali_syndrome#History

> Urine alkalinization will also slow down your kidney's excretion of alkaline drugs and their metabolites. And speed up excretion of acidic drugs. So... overall good or bad?

Depends if you took too little or too much.

But even if you took too little, the drug may get broken down in other ways before you get rid of it for good.

Re: Trials begin on lozenge that rebuilds tooth enamel

#184
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Describe your diet in detail

Re: Trials begin on lozenge that rebuilds tooth enamel

#186
post #31

> In addition, the researchers are investigating a gel or solution with the engineered peptide to treat hypersensitive teeth. This problem results from weakness in the enamel that makes the underlying dentin and nerves more vulnerable to heat or cold. Most common products currently on the market can put a layer of organic material on the tooth and numb nerve endings with potassium nitrate, but the relief is only temp…

Check into acid reflux aka GERD that could be a big part of your problem.

I was to the point where eating a room temperature banana in mid summer was too cold for my teeth. My dentist figured out it was the acid I was coughing up getting on my teeth.

I also grind my teeth but that's more mechanical the acid affects all surfaces of my teeth. Sensodyne toothpaste or similar helps a bit if I remember to not rinse it off.

Re: Trials begin on lozenge that rebuilds tooth enamel

#187

Earlier quoted context omitted.

> (it doesn’t hurt!) It doesn't hurt for you . Some people, including myself, have had root canals that have almost caused worse pain than when I was in the ICU.

Yeah it took me decades to learn that the pain of getting a cavity filled isn't normal. I thought the freezing helped and that the ice pick jab causing lightning of pain down my spine was what everyone suffered. A dentist finally slowed down. Noticed my tears. Asked. Had a conversation. Tried freezing me in other places. Worked perfectly. She guessed that my nerves are anatomically weird.

I'm with you. Cross innervation[0] is hell!

[0] https://pubmed.ncbi.nlm.nih.gov/11505257/

Re: Trials begin on lozenge that rebuilds tooth enamel

#188

Earlier quoted context omitted.

Can you describe more specifically where the Botox was injected? What muscle(s) did it paralyze?

I don’t know the muscles but maybe someone here can chime in with the specific names from this very unscientific description: on each side of my head kind of near my temples and on each side of my jaw near the corner(?) bone. (Really regretting never having taken an anatomy class...) If you put your finger on your earlobe and pull it maybe an inch forward I would say it was about there. My doctor kindly used some sor…

Could you be referring to the masseters? Those are the muscles you use for chewing.

Re: Trials begin on lozenge that rebuilds tooth enamel

#190

Earlier quoted context omitted.

> (it doesn’t hurt!) It doesn't hurt for you . Some people, including myself, have had root canals that have almost caused worse pain than when I was in the ICU.

You don't ask for drugs? Ask for drugs. I always get Xanax and it basically puts me out through the whole thing. I have, err... had a lot of root canals. I'd think the bigger concern with a root canal is the not-insignificant likelihood they will break your jaw. Or not get the whole root out, causing an infection and need to get the procedure done again. (Never have a dentist do your root canal, folks)

If not you dentist, then who would do the root canal?
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