11–20 of 426 posts
I’m personally sceptical of putting too much faith in this, we’ve already seen a number of variants. Over my lifetime? Who knows what mutations we’ll see.
What happened in Manaus/Brazil(high re-infection rate even after the city reached herd immunity) shows that's not that simple and they clearly state it "though viral variants could dampen some of the protection they offer"
Getting influenza antibodies once only protects you for that season, until a new strain emerges few months down the line.
Earlier quoted context omitted.
Probably that the vaccine is somewhat irrelevant: though that's up for grabs since what your body targets vs. what the vaccine targets will be subtly different. I'm more interested that this means that quite likely, COVID-19 will be eradicated: with not many advantageous mutation pathways, and if vaccines are conferring immunity forever, it's pretty much going to be burned out of the population one way or the other.
>with not many advantageous mutation pathways I was under the impression that any mutations to the spike proteins would make the current vaccines useless and would require changes to the vaccines just like the flu shot . Isn't this the case ?
> The study provides evidence that immunity triggered by SARS-CoV-2 infection will be extraordinarily long-lasting. Does it? I think this pop-science article overly simplifies antibodies and immunity... I'm no doctor myself, but as was explained to me by my doctor friends (who however are not specialists in this subtopic either), there's many different layers to the immune system. It's entirely possible to have antib…
Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?
>People who have already had confirmed covid-19 might only need a single dose of a mRNA vaccine, two small studies have indicated.
Two weeks after a single dose of vaccine, people who had previously had covid-19 had antibody concentrations that were as high, or up to 10 times higher, than the levels seen in uninfected people who had received two doses of the vaccine.
> The study provides evidence that immunity triggered by SARS-CoV-2 infection will be extraordinarily long-lasting. Does it? I think this pop-science article overly simplifies antibodies and immunity... I'm no doctor myself, but as was explained to me by my doctor friends (who however are not specialists in this subtopic either), there's many different layers to the immune system. It's entirely possible to have antib…
I’m personally sceptical of putting too much faith in this, we’ve already seen a number of variants. Over my lifetime? Who knows what mutations we’ll see.
Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?
> Ellebedy’s team has observed early signs that Pfizer’s mRNA vaccine should trigger the production of the same cells. But the persistence of antibody production, whether elicited by vaccination or infection, does not ensure long-lasting immunity to COVID-19. The ability of some emerging SARS-CoV-2 variants to blunt the protective effects of antibodies means that additional immunizations may be needed to restore levels, says Ellebedy. “My presumption is we will need a booster.”
The idea seems to be that an infection is like a single dose of the vaccine, so you still need another shot for the best immunity.