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Had Covid? You’ll probably make antibodies for a lifetime

nature.com

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Re: Had Covid? You’ll probably make antibodies for a lifetime

#3

Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?

Probably that the vaccine is somewhat irrelevant: though that's up for grabs since what your body targets vs. what the vaccine targets will be subtly different.

I'm more interested that this means that quite likely, COVID-19 will be eradicated: with not many advantageous mutation pathways, and if vaccines are conferring immunity forever, it's pretty much going to be burned out of the population one way or the other.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#4

Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?

Probably nothing at all, the mRNA vaccine will just prompt the body to make even more antibodies against the variants from the vaccine.

I expect having stronger flu-like side-effects on the first injection instead of the usual second mRNA injection. For this reason, if you had diagnosed COVID, in France you'll be injected a single dose of mRNA vaccine and be considered immune.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#5
> The study provides evidence that immunity triggered by SARS-CoV-2 infection will be extraordinarily long-lasting.

Does it? I think this pop-science article overly simplifies antibodies and immunity...

I'm no doctor myself, but as was explained to me by my doctor friends (who however are not specialists in this subtopic either), there's many different layers to the immune system. It's entirely possible to have antibodies and/or antibody-producing capacity in your body, yet not be "immune" - if by "immune" we mean that you cannot get the illness, both in the sense that you don't get ill, and in the sense that you don't become asymptomatic carrier (i.e. the virus starts replicating in your body, but not enough to make you feel "ill" effects) (both of which are kind-of important if you want to stop a pandemic). Long-term immune system "memory cells" (B-cells) might still need time to be activate and start producing antibodies, so you can get infected, ill & a spreader, but not seriously ill because your immune system re-awakens and starts producing antibodies and you recover much quicker than you otherwise would. (This whole mechanism is the reason why you need booster shots of some vaccines.)

This is, of course, based mainly on experience from non-coronavirus like viruses. This one might be different.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#6
post #3

Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?

Probably that the vaccine is somewhat irrelevant: though that's up for grabs since what your body targets vs. what the vaccine targets will be subtly different. I'm more interested that this means that quite likely, COVID-19 will be eradicated: with not many advantageous mutation pathways, and if vaccines are conferring immunity forever, it's pretty much going to be burned out of the population one way or the other.

>with not many advantageous mutation pathways

I was under the impression that any mutations to the spike proteins would make the current vaccines useless and would require changes to the vaccines just like the flu shot . Isn't this the case ?

Re: Had Covid? You’ll probably make antibodies for a lifetime

#7

Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?

I think you might be referring to those social media posts that suggest that the mRNA vaccines undo the immunity afforded by an infection. Those stories are false, here's more information: https://factcheck.afp.com/american-red-cross-accepts-plasma-...

Re: Had Covid? You’ll probably make antibodies for a lifetime

#8

Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?

Yes i am studying this and have data on covid + post covid quarterly antibody markets followed by one dose pfizer and monthly markers.

In a nutshell - covid patients have sustained antibodies, non covid with vaccine groups have faster decay from Peak concentration.

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