> Let's discuss in public, I think others might be interested. What do you mean by scale? Are you saying that the biologica are too expensive and you are looking for cheaper solutions? Apart from the price AFAIK they are the best known solution.
In that case hurting yourself trying to find sth. cheaper is not worth it, because: a) it is bad for you b) it doesn't help others either, since even if your special cocktail ends up working for you it will most likely not work for others.
OK, lets start with just the official stuff that they actually admit.
HUMIRA can cause serious side effects including hepatitis B infection in carriers of the virus, allergic reactions, nervous system problems, blood problems, heart failure, certain immune reactions including a lupus-like syndrome, liver problems, and new or worsening psoriasis.
Do you see a trend here? Auto-immune treatment causes more auto-iummune diseases. Thats real sus to me.
> I would focus on making tnf-a blockers cheaper, probably by circumventing or straight out ignoring the patents. This stuff is not rocket science anymore.
You are actually trained at this and I am not but I do not understand why youy would focus on alpha when beta is far more cytotoxic. Like I said, I don't have your training but that seems odd given the rate of colo rectal cancer in Crohn's patients.
Given that the entire family of drugs refers to Cytokines which is cell-death it seems a bit asinine to focus on alpha.
> Have you researched the prices in other countries? Looks like in Europe its below 2k€ per month but more around 20k in the us? Whats the price in India?
India does not sell the name brand I am familiar with; they have Zydus' Exemptia and its around $4,500 USD.
> What do you mean by scale?
I mean scale. Given that N patients have Crohn's and wish to treat themselves with Z. If Z is a finite resource what are the obstacles to Z being produced and distributed at a "scale" great enough to reach each patient, for life.
> it doesn't help others either, since even if your special cocktail ends up working for you it will most likely not work for others.
Please provide some form of empirical evidence to support this position, I was saying in private because I have actual clinical outcomes that i can report form myself and a number of others, but doing so publicly is not ethical or legal; HIPPA and all.
Can you expand a bit more on what you meant when you said you were a researcher? Possibly point me to a white paper or jupiter notebook, anything so that I may get a better understanding of your work.
I do not even know how to begin to address the reductive nature of pharma disco and production "not being rocket science" other than to state the obvious, yes it's not rocket science its bio chem.
I am sure i'm just missing something given that you work professionally in the field.
FYI: It has nothing to do w/ the price at all, even on the worst medical/medicare plan humera is only 250 for 2 viles and it was less, now it just has the extra lux tax.