Instagram can actually be a nice place, if used as a platform to look at cool pictures and not at all as a social network. I never added any friends or family, I just follow accounts and topics I'm interested in. So my feed is almost entirely pixel art, cool architecture, and retro console mods, and it's very pleasant. Considering they're Facebook-owned, I see surprisingly little effort to cram low-effort garbage dow…
* Consumer-only: simply following artists/whatever and not contributing anything
* Family and friends: Sharing pictures of your holiday/kid/cat/food with people you know
* Influencers and wannabe influencers: Actively seeking to grow an audience
I don't think between 1 & 2 anyone can say one is better than the other, they're two quite different modes of using the app. Number 2 obviously can lead to people wondering why their 15th funny picture of their cat didn't get as many likes, and it's for this group that I think turning off likes altogether can help the most.
I would expect, though, that if everyone in a family-and-friends circle were turning off their likes, comments would become a proxy for likes, and there would be an expectation to add "nice!", "beautiful!" "how funny!" to posts, and then a similar feeling when posts don't get any response.