Drunk as a Lord: the Regency Bottle Men • Hacker News Board

Re: Drunk as a Lord: the Regency Bottle Men

#41

Post by rkk3 » Tue, May 25, 2021, 4:15 PM UTC

nicoburns wrote: post #9

sgt101 wrote: post #6

Earlier quoted context omitted.

I am no MD - but I am curious, perhaps someone who has a clue can comment on what I am going to say. I believe that Liver Cirrhosis is caused by scaring due to fat being retained in the liver. I understand that fat is retained when the liver is metabolizing alcohol, and that if this is a short term thing then the liver can expel the fat and no scaring occurs. But if you persistently force your liver to metabolize alc…

Not a medical professional either, but I once heard that keeping 2 consecutive days out of every week alcohol free as sufficient for preventing liver cirrhosis.

You would need to stop less frequently and for a longer interval to see health benefits.

For heavy drinkers stopping and starting every week would cause withdrawals, which is dangerous and often worse than consistent heavy drinking. Weekend Warriors are actually doing a lot of damage to their body for this reason.

Re: Drunk as a Lord: the Regency Bottle Men

#42

Post by tomlagier » Tue, May 25, 2021, 5:03 PM UTC

elktea wrote: post #14

sgt101 wrote: post #6

Earlier quoted context omitted.

I am no MD - but I am curious, perhaps someone who has a clue can comment on what I am going to say. I believe that Liver Cirrhosis is caused by scaring due to fat being retained in the liver. I understand that fat is retained when the liver is metabolizing alcohol, and that if this is a short term thing then the liver can expel the fat and no scaring occurs. But if you persistently force your liver to metabolize alc…

It's been shown (in rats) that saturated fats are protective against cirrhosis and unsaturated fats (linoleic acid in this case) are required for liver injury. Might explain why some people can drink like fish and have perfectly healthy livers while others suffer badly. https://pubmed.ncbi.nlm.nih.gov/2915600/

Just listened to a Revisionist History episode that called out the harms of over-consumption of linoleic acid. Apparently the shift away from animal and towards vegetable oils in the '70s and '80s caused a lot of adverse health effects because we now consume multiples of the amount of linoleic acid that we did in previous generations.

Podcast: https://blog.simonsays.ai/the-basement-tapes-with-malcolm-gl...

(Somewhat biased, but still a good summary of the research) article on linoleic acid: https://theecologist.org/2014/feb/24/linoleic-acid-overwhelm...

Re: Drunk as a Lord: the Regency Bottle Men

#43

Post by nicoburns » Tue, May 25, 2021, 9:51 PM UTC

rkk3 wrote: post #41

nicoburns wrote: post #9

Earlier quoted context omitted.

Not a medical professional either, but I once heard that keeping 2 consecutive days out of every week alcohol free as sufficient for preventing liver cirrhosis.

You would need to stop less frequently and for a longer interval to see health benefits. For heavy drinkers stopping and starting every week would cause withdrawals, which is dangerous and often worse than consistent heavy drinking. Weekend Warriors are actually doing a lot of damage to their body for this reason.

What makes withdrawals dangerous?

Re: Drunk as a Lord: the Regency Bottle Men

#44

Post by rkk3 » Tue, May 25, 2021, 10:39 PM UTC

nicoburns wrote: post #43

rkk3 wrote: post #41

Earlier quoted context omitted.

You would need to stop less frequently and for a longer interval to see health benefits. For heavy drinkers stopping and starting every week would cause withdrawals, which is dangerous and often worse than consistent heavy drinking. Weekend Warriors are actually doing a lot of damage to their body for this reason.

What makes withdrawals dangerous?

Alcohol is a very strong depressant, your nervous system will adjust to it and will be over stimulated if you cut it off abruptly. A minor symptom of this would be anxiety... severe symptoms could be psychosis, seizures or death. https://en.wikipedia.org/wiki/Alcohol_withdrawal_syndrome

There is also a positive feedback effect called Kindling, from sudden withdrawals, which makes subsequent ones worse. https://en.wikipedia.org/wiki/Kindling_(sedative%E2%80%93hyp...

Re: Drunk as a Lord: the Regency Bottle Men

#45

Post by op00to » Tue, May 25, 2021, 11:08 PM UTC

Applejinx wrote: post #25

op00to wrote: post #16

Earlier quoted context omitted.

This makes little sense. I can drink 6 bottles a day, but as long as I respect the lord on the weekend my liver’ll be ok?

Best stick to drinking the contents…

The molten glass really coats the throat.

Re: Drunk as a Lord: the Regency Bottle Men

#46

Post by euroderf » Wed, May 26, 2021, 5:37 AM UTC

Kosirich wrote: post #21

sgt101 wrote: post #6

Earlier quoted context omitted.

I am no MD - but I am curious, perhaps someone who has a clue can comment on what I am going to say. I believe that Liver Cirrhosis is caused by scaring due to fat being retained in the liver. I understand that fat is retained when the liver is metabolizing alcohol, and that if this is a short term thing then the liver can expel the fat and no scaring occurs. But if you persistently force your liver to metabolize alc…

The example I gave got my dad and me into discussion about what is the effect of choice of alcohol which a person (mis)uses excessively, on the probability and severity of alcoholism related illnesses. To put it bluntly, is getting frequently drunk from beer/wine less harmful long term than getting drunk from spirits?

Would the damage depend on the pacing ? I recall reading an opinion that spirits are more harmful because they ramp up one's blood alcohol level more quickly, and this in and of itself causes a particular harm.