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Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

biopharma-reporter.com

1–10 of 21 posts

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#2
Bit offtopic but I fully believe that if PrEP had been discovered in the 80s that no vaccine would ever come about because public enthusiasm in conjunction with PrEP would have eradicated the disease. Nowadays, 3/5 people you ask don’t even know what PrEP is.

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#3
We need more diversification in the supply chain for the capsule/carrier technology. Right now, this feels like gastronomical chemistry, only 4-star chefs can play.

We need India able to pump this stuff out by the billions, like they do for other drugs.

Flu, HIV

can mRNA handle Malaria, then TB? Parasite, and Bacterial.

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#4
post #2

Bit offtopic but I fully believe that if PrEP had been discovered in the 80s that no vaccine would ever come about because public enthusiasm in conjunction with PrEP would have eradicated the disease. Nowadays, 3/5 people you ask don’t even know what PrEP is.

What is PrEP?

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#5
post #3

We need more diversification in the supply chain for the capsule/carrier technology. Right now, this feels like gastronomical chemistry, only 4-star chefs can play. We need India able to pump this stuff out by the billions, like they do for other drugs. Flu, HIV can mRNA handle Malaria, then TB? Parasite, and Bacterial.

> this feels like gastronomical chemistry, only 4-star chefs can play

It’s literally a new biomedical platform. Only 4-star chefs can even guess at how the kitchen should be stocked.

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#6
post #2

Bit offtopic but I fully believe that if PrEP had been discovered in the 80s that no vaccine would ever come about because public enthusiasm in conjunction with PrEP would have eradicated the disease. Nowadays, 3/5 people you ask don’t even know what PrEP is.

Even with PrEP available, HIV would likely still have become a big problem in places where healthcare is not as readily available, especially in Africa, where it is still a major concern today.

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#7
post #4
post #2

Bit offtopic but I fully believe that if PrEP had been discovered in the 80s that no vaccine would ever come about because public enthusiasm in conjunction with PrEP would have eradicated the disease. Nowadays, 3/5 people you ask don’t even know what PrEP is.

What is PrEP?

https://www.cdc.gov/hiv/basics/prep.html

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#8
post #4
post #2

Bit offtopic but I fully believe that if PrEP had been discovered in the 80s that no vaccine would ever come about because public enthusiasm in conjunction with PrEP would have eradicated the disease. Nowadays, 3/5 people you ask don’t even know what PrEP is.

What is PrEP?

[deleted]

Re: Moderna to take mRNA flu and HIV vaccines into Phase 1 trials this year

#9
post #4
post #2

Bit offtopic but I fully believe that if PrEP had been discovered in the 80s that no vaccine would ever come about because public enthusiasm in conjunction with PrEP would have eradicated the disease. Nowadays, 3/5 people you ask don’t even know what PrEP is.

What is PrEP?

PrEP is a cocktail of anti-HIV drugs that prevents infection if taken daily. It’s been combined into convenient single-dose pills called Truvada and Descovy. These drugs have a high price tag, but insurance covers it, and if you don’t have insurance the manufacturer Gilead will reimburse you. Great for people like me in the US. But it’s not widely distributed in developing countries where HIV is killing a lot more people. That’s where a vaccine would have the most benefit.
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