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No safe level of alcohol for brain health: observational cohort study [pdf]

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Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#81
post #56
post #19

Median alcohol intake was 13.5 units ( 102g) weekly That was among people who drank at all; for reference, that's just under two standard drinks per day, which is apparently what the UK considers the threshold of "low risk".

> Glasses were converted to UK units as follows: red or white wine = 1.7 units; fortified wine=1.2 units; pint = 2.4 units; spirits = 1 unit; other (e.g. alcopops) = 1.2 units. Amounts were also converted to grams pure ethanol (1 UK unit=8g) to aid international comprehension and comparison. Can someone explain these numbers to me? They claim to measure one “standard drink” (all of which are equal), yet each variant…

[deleted]

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#82
post #61
post #26

When I was younger, reading about the history of Prohibition in the US, I thought it was completely bonkers. The idea that alcohol was even worth a ban, let alone whether such a ban could be enforced, was silly to me. But the more I read about stuff like this, the more I realize that alcohol isn't special among the various things we call "drugs". It's not good for your physical health, and "everything in moderation"…

> Alcohol should be no different, but the social and cultural pressure around it makes it different. I don't think it's just that. I think it's also that (potentially in quite modest quantities) alcoholic drinks are an important part of/accompaniment to some cuisines, providing a balancing sweetness, acidity, and so on. I find the idea of steak without a glass of robust red wine terribly disappointing. Seafood soup w…

Similar to your own refined sensibilities, I find the idea of a rare weekend brunch without at least one fruity mimosa, or two, or three, quite disappointing.

Or celebrating New Years without a perfectly crisp champagne, or prosecco. Preferably a Dom Perignon vaguely reminescent of tart green apples. Conversely, he bargain hunter in me loves the liquid sunshine in a hayfield that is Zardetto DOC.

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#83

Welp, that does it. I'm definitely not getting smarter, and can't afford to lose what little I'm still holding onto. I live in a US state where weed is legal, and I was discussing this with a friend: it's starting to seem like a terrible idea to drink at all if weed is available and has lesser harmful effects. For me personally, it comes down to that I'd hate for my kids to see me using weed, but I acknowledge that's…

Weed absolutely has cognition issues, especially among young people.

http://m.pnas.org/content/109/40/E2657.full (2012)

> "Persistent cannabis users show neuropsychological decline from childhood to midlife"

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#84
post #11

Submission title gets it wrong. What the study found was that of the total variance in the amount of gray matter, only 0.8% of that variance could be explained by alcohol consumption.

Submitted title was "Behavioral study finds 0.8% gray matter loss from alcohol consumption [pdf]". Submitters: please follow the site guidelines, which say: "Please use the original title, unless it is misleading or linkbait; don't editorialize."

https://news.ycombinator.com/newsguidelines.html

If you want to say what you think is important about an article, that's fine, but do it by adding a comment to the thread. Then your view will be on a level playing field with everyone else's: https://hn.algolia.com/?dateRange=all&page=0&prefix=false&so...

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#85
post #26

When I was younger, reading about the history of Prohibition in the US, I thought it was completely bonkers. The idea that alcohol was even worth a ban, let alone whether such a ban could be enforced, was silly to me. But the more I read about stuff like this, the more I realize that alcohol isn't special among the various things we call "drugs". It's not good for your physical health, and "everything in moderation"…

> the more I realize that alcohol isn't special among the various things we call "drugs". But it is. Humans are pretty good at metabolizing alcohol. Other species are not as good (carnivores in particular). Why is that? Every day bacteria in your gut produce alcohol. Every day you ingest it. Some percentage of carbs get converted daily. It's conceivable that our bodies are fine with small amounts.

I wonder if the OP accounted for the effects of carbs in general? Could alcohol be just another carb?

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#86

Welp, that does it. I'm definitely not getting smarter, and can't afford to lose what little I'm still holding onto. I live in a US state where weed is legal, and I was discussing this with a friend: it's starting to seem like a terrible idea to drink at all if weed is available and has lesser harmful effects. For me personally, it comes down to that I'd hate for my kids to see me using weed, but I acknowledge that's…

Weed absolutely has cognition issues, especially among young people. http://m.pnas.org/content/109/40/E2657.full (2012) > "Persistent cannabis users show neuropsychological decline from childhood to midlife"

That's just adolescents, so I would presume not applicable to OP.

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#87

Earlier quoted context omitted.

Not sure why you're being downvoted. Both are extremely safe compared to ethanol — in terms of both self-harm and harm inflicted upon others.

Tons of studies show that weed effects emotional processing, increases risk of of sudden psychosis, and yes, even gray matter loss. [1] This idea that weed is safe due in part to its associations with "Nature" is really a social fabrication. People just fought for another thing they wanted to imbibe that wrecks us in another, not necessarily equivalent, way. Personal experience is it's one of the few recreational dru…

> Personal experience is it's one of the few recreational drugs I can't handle as I experience extreme paranoia

I get those too. After considering it for decades, I'm fairly convinced it's due to my psychological makeup - specifically fearing an unmasked loss of control.

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#88

Earlier quoted context omitted.

Well, there's this newish hangover-free thing: https://www.sentiaspirits.com/ Has some reviews floating around the internet: https://metro.co.uk/2021/01/22/alcohol-free-spirit-sentia-pr... The creator, David Nutt, has a long history of trying to bring attention to the problems alcohol brings. https://en.wikipedia.org/wiki/David_Nutt

Does anyone know of a way to get this shipped to the USA?

If you're ok with comparable alternatives, Amazon sells a variety of non-alcoholic wines.

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#89

Earlier quoted context omitted.

> the more I realize that alcohol isn't special among the various things we call "drugs". But it is. Humans are pretty good at metabolizing alcohol. Other species are not as good (carnivores in particular). Why is that? Every day bacteria in your gut produce alcohol. Every day you ingest it. Some percentage of carbs get converted daily. It's conceivable that our bodies are fine with small amounts.

I wonder if the OP accounted for the effects of carbs in general? Could alcohol be just another carb?

It does also compare with BMI and if I recall from my skimming a higher BMI also correlated with higher alcohol intake. Alcohol does get used as energy for your body meaning your body isn’t using up the carbs you had, and you end up gaining weight.

Re: No safe level of alcohol for brain health: observational cohort study [pdf]

#90
I started drinking about 8. Drank heavy thru high school. Tapered down and quit by 24.

The only time I miss it is after some TV series bombards me with episode-after-episode of all day drinking w/o the expected consequences. Otherwise I'd never even think about alcohol.

I'm generally a better living thru chemistry guy, just not w/ alcohol. I'm kind of put off by the stinky breath and how jail feels like it's one drink away.

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