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Was cancer less likely in a pre-industrial world?

nationalgeographic.com

141–150 of 173 posts

Re: Was cancer less likely in a pre-industrial world?

#141

The modern age has possibly removed some carcinogens like inhaling smoke from (bon)fires, mycotoxins from spoilt food, nutritional illiteracy and unsanitary conditions. But the modern age has introduced a lot of new ones like tobacco, food additives, sugar, gluten, radiation, asbestos, industrial processing of food, pesticides, sedentary lifestyle.

Gluten is a protein, doesn't that mean it's broken down into amino acids by digestion?

Re: Was cancer less likely in a pre-industrial world?

#143
The dismissive comments here are confusing to me. Of course this is a valuable thing to study, because without it we won't know if there are factors about our modern industrial society that could be altered to increase our lifespans even more. Or is 80 years just "good enough" and people don't want to live to 160? Also if we find that cancer was less prevalent before, that's a useful data point for how much cancer can be avoided in a hypothetical ideal situation that we should perhaps shoot for.

Re: Was cancer less likely in a pre-industrial world?

#144
post #140
post #83

Earlier quoted context omitted.

Moles don't stop growing primarily because of telomere length but because the human genome has effective methods of controlling cancer. You get cancer something like 4 times a day but the cells are terminated. (It is possible telomeres play some part in this, but I have never seen it proposed.) What you are likely trying to broach is the question "do organisms evolve to die?" the answer to which is "yes." This was or…

Imagine humans who can't die from old age: how many would choose to do anything dangerous? Would you risk your life crossing a road? Working on a construction site?

https://gizmodo.com/if-you-could-only-die-in-sudden-accident...

Re: Was cancer less likely in a pre-industrial world?

#145
post #70

Earlier quoted context omitted.

Is there any evidence supporting this hypothesis?

For context: the molecular shape of gluten causes dough to hold better. Wheat with more gluten gives softer bread which rises better. Hence why gluten is so prevalent in domesticated wheat.

We’ve been optimizing stuff for palatability and processing since we started domesticating wheat. I am going to need a better argument about why gluten is special.

Re: Was cancer less likely in a pre-industrial world?

#146
post #140
post #83

Earlier quoted context omitted.

Moles don't stop growing primarily because of telomere length but because the human genome has effective methods of controlling cancer. You get cancer something like 4 times a day but the cells are terminated. (It is possible telomeres play some part in this, but I have never seen it proposed.) What you are likely trying to broach is the question "do organisms evolve to die?" the answer to which is "yes." This was or…

Imagine humans who can't die from old age: how many would choose to do anything dangerous? Would you risk your life crossing a road? Working on a construction site?

I had the same question reading Tolkien. The Elves don't age. They live amogst deities and have first hand knowledge of the creator of the universe. More so, they even know beyond doubt the fate that awaits those who die from other means: awaiting the end of the world in the comparatively boresome Halls of Mandos. Why would any Elf go to war as often as they do in Tolkien's universe seemed unexplicable.

Re: Was cancer less likely in a pre-industrial world?

#147
post #140
post #83

Earlier quoted context omitted.

Moles don't stop growing primarily because of telomere length but because the human genome has effective methods of controlling cancer. You get cancer something like 4 times a day but the cells are terminated. (It is possible telomeres play some part in this, but I have never seen it proposed.) What you are likely trying to broach is the question "do organisms evolve to die?" the answer to which is "yes." This was or…

Imagine humans who can't die from old age: how many would choose to do anything dangerous? Would you risk your life crossing a road? Working on a construction site?

Reminds me of Death Love Robot Season 2 ;)

Re: Was cancer less likely in a pre-industrial world?

#148

Earlier quoted context omitted.

They are extinct, so supporting his hypothesis ? It's not like evolution is a design process in which something gets "traded off" - random shit happens, something sticks.

> They are extinct, so supporting his hypothesis Or they were hunted to death by organised groups of early humans. Wales are probably only surviving because their environment is so foreign to humans.

Eg, Origins of the Human Predatory Pattern: The Transition to Large-Animal Exploitation by Early Hominins

https://www.journals.uchicago.edu/doi/10.1086/701477

Re: Was cancer less likely in a pre-industrial world?

#149
post #12

One thing which I always thought of, but which the article doesn't mention, is age. Especially older people seem more prone to cancer, so in my mind a lower life expectancy will naturally lead to a lower cancer rate, as people die before cancer "is able to get them". Or am I missing something?

I remember reading about a drug study where people were given a drug for (I don't recall) and people started dying of heart attacks.

Turns out it was curing the , but the next thing the population would statistically die of was: heart attacks.

Re: Was cancer less likely in a pre-industrial world?

#150
post #140
post #83

Earlier quoted context omitted.

Moles don't stop growing primarily because of telomere length but because the human genome has effective methods of controlling cancer. You get cancer something like 4 times a day but the cells are terminated. (It is possible telomeres play some part in this, but I have never seen it proposed.) What you are likely trying to broach is the question "do organisms evolve to die?" the answer to which is "yes." This was or…

Imagine humans who can't die from old age: how many would choose to do anything dangerous? Would you risk your life crossing a road? Working on a construction site?

It would be interesting to see how humanity would react if that were true. If people had to worry about their actions now causing consequences later for themselves and not just other people's children, I'd imagine we wouldn't be polluting our planet so much. Maybe it would also cause us to take expanding civilisation beyond earth a lot more seriously. Or maybe it would just make wars more vicious. It wouldn't be enough to control other countries, the goal would be extermination to make room for children.
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