51–60 of 125 posts
It's only a matter of time before this is used as a standard performance enhancement trick for endurance sports. Only saying this half-jokingly.
If so, it sounds like a much cheaper alternative to ECMO in some cases.
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I have a hunch future generations will look back on our animal experimentation similar to how we look back on human experimentation, horrified but with a silver lining (and most people just prefer not to think about it much at all). I'm very much against both, but I recognize the important advances they've made for medicine. I also recognize that most of the advances for animals don't translate to humans, and some ev…
Nazi human experimentation was torture done under the auspices of junk-science. It was recognized as such even by the people of that time period. Nothing that they studied is taught in science programs anywhere today.
http://www.bu.edu/articles/2019/learn-from-nazi-medical-rese...
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> we justify experimenting on a known serial killer if the experiment will save a million children's lives in the next 10 years? Without hesitation. A serial killer is someone who believes murder is acceptable and turnabout is fair play. Provided they are actually guilty there is little that is unjustified when dealing with willfully violent actors such as that. Add in now this person who has harmed society can be us…
"Don't worry, that willcipriano guy we experimented on and murdered was a known serial killer. Never mind that he was a political dissident or whatever."
Two things really stood out in this article. One is how brutal animal experimentation can be. The other is the opening line.
Back when I was a pre-med, my first summer research internship was in a cancer lab. After a couple of weeks of cell culture and autoclaving stuff, they let me start working with the mice. They were inducing lung cancer in them to test some novel compound that was supposed to cure the cancer. Every day, I'd have to go to the mice room, swap in fresh water and food, and then bag all the dead mice individually in rubber…
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Yea... poor mice.. hopefully they weren't awake.
I have a hunch future generations will look back on our animal experimentation similar to how we look back on human experimentation, horrified but with a silver lining (and most people just prefer not to think about it much at all). I'm very much against both, but I recognize the important advances they've made for medicine. I also recognize that most of the advances for animals don't translate to humans, and some ev…
Two things really stood out in this article. One is how brutal animal experimentation can be. The other is the opening line.
I read a lot of medical research papers, and I've been thinking about this recently. Every time I read about a rat being "euthanized" or "sacrificed", when they have neuropathy induced by toxins, when they have limbs amputated, when they have their spine severed... I can't help but pause for a moment and think about that animal. I wonder if there are any good estimates of how many rats, rabbits, dogs and otherwise ar…
> Is there, realistically, anything that would change this?
In all confidence, nothing is going to replace animal models in science for decades to come(at least when we talk about biology). Yes, you can study development and disease in cell culture or organoids to some extent. But those don’t match the dynamics of a fully-functioning organism. Even though findings from mouse experiments often don’t translate well to humans, it’s our best bet. Computational biology can reduce the amount of experiments you need to do. For example, you can try to predict drug toxicity or identify key regulators of a certain cell type. But there’re always false positives(gene-regulatory networks are like 90% FP) and you always need to go back to the lab.
If anything, I hope for more in-vivo experiments with the developments in CRISPR.
[0] https://en.wikipedia.org/wiki/Monument_to_the_laboratory_mou...