Earlier quoted context omitted.
I would put money on COVID not happening at all if all buildings had 10 air refreshes per hour, and that air either coming from the outdoors or going through a HEPA filter. I would guess an analysis of workplace COVID rates would see a strong correlation between workplaces with and without filtration in their AC systems.
The highest infection rates are still short range though. This, combined with being a new virus would still be similar to today.
With say 10 air changes per hour (injecting at the ceiling and extraction at the floor), and a 3m high building, you can expect airflow downwards at about 1 cm per second. That means there is perhaps only a 30 second window for a particular pathogen to hit someone else's nose before being pulled to below face level.
It's not nil, but I think that would lower transmission rates by a sufficient factor for COVID (and many other diseases) to become extinct.