I've read a ton of speculative fiction over the years (I'm in my mid 50's) but had never gotten around to reading anything by Ursula Le Guin. One day whilst catching up on some anarchist reading I found The Dispossessed listed in a "top x books for anarchists" or some such thing. And it seemed like no better time than at that moment to dip into the Le Guin's work.
I decided I'd start reading her scifi novels in near chronological order and began with The Left Hand of Darkness which I found devastatingly good. This is the one mentioned in the interview where Genly Ai the observer is embedded on a planet where the humanoid species are in the main genderless and only become male or female during a period of "kemmer" to reproduce. I can't do it justice here but I couldn't put the book down.
Next up were the three previous novels; Rocannon's World, Planet of Exile and City of Illusions. These are contained in a handy single volume published under the S.F. Masterworks imprint. All of these are also excellent novels, if a little short.
I've just started The Dispossessed and thus far it's holding my attention.
I think if you've never considered reading Le Guin's scifi then I can definitely recommend from the limited sampling I gotten through so far. Some folks might be put off by how old these novels are, but Le Guin cleverly shy's away from using technology as a plot driver (perhaps with the exception of the "ansible") so they don't feel dated. Her writing and story telling is as fresh today as it probably was back in the 60's and 70's.
Also, and I almost forgot, Le Guin's short story "The Ones Who Walk Away from Omelas" which is quite disturbing and thought provoking.