Live data from Hacker News

Doctors investigate mystery brain disease in Canada

bbc.com

301–310 of 311 posts

Re: Doctors investigate mystery brain disease in Canada

#301
post #26
post #17

Earlier quoted context omitted.

You get plenty of excitotoxins from eating MSG which may be causing diseases too. The amount of msg in commercial food has doubled the last decade apparently. So much we don’t know about the body and what we put in it.

I hadn't heard this claim about MSG before. I did a quick search on Google, but didn't find anything that looked remotely reputable. I did a quick search on Google Scholar, and everything seemed to be refuting the claim. Do you have any sources you can share?

Apologies for posting this I wish I could delete it

Re: Doctors investigate mystery brain disease in Canada

#302

Earlier quoted context omitted.

You do not understand the concept: I decide I want to try a bit of "something new", and I pay someone to induce a Capgras delusion in me. At which point, my wife seems like an imposter. I wish to have sex with this new person, and I am also sure my real wife has given me permission to, prior to this. You can tell me as much as you like that it's "really" my wife, but, in my delusion, I am quite sure it's just someone…

I do understand the concept. You have not changed my understanding with this description. If I am suffering a delusion, and you know that, then you know that I am not mentally competent. You know that, if I agree to something, I do not correctly understand what I am agreeing to. Any expression of consent you extract from me is invalid.

This seems extreme. You are consenting to be deluded, knowing everything that will come afterwards. And the consenting during as well

Re: Doctors investigate mystery brain disease in Canada

#303

Earlier quoted context omitted.

You do not understand the concept: I decide I want to try a bit of "something new", and I pay someone to induce a Capgras delusion in me. At which point, my wife seems like an imposter. I wish to have sex with this new person, and I am also sure my real wife has given me permission to, prior to this. You can tell me as much as you like that it's "really" my wife, but, in my delusion, I am quite sure it's just someone…

I do understand the concept. You have not changed my understanding with this description. If I am suffering a delusion, and you know that, then you know that I am not mentally competent. You know that, if I agree to something, I do not correctly understand what I am agreeing to. Any expression of consent you extract from me is invalid.

Yes, that’s why you’d get consent before hand

Re: Doctors investigate mystery brain disease in Canada

#304

Earlier quoted context omitted.

I think the idea is that if you wanted to spice up a marriage with an affair, you could use this to "cheat" on your spouse with your spouse. Both parties would be consenting the whole time. One would just think they are cheating.

Oh, I understand the concept. It's broken. If I am "consenting", but not to the action that's actually happening, I am not, in fact, consenting. If I believe that I am consenting to sex with someone that's not my husband, in that moment I am not consenting to sex with my husband. If they then have sex with me, knowing that that is my state of mind , that is non-consensual.

This discussion boils down to if consent must be continually given or if you can give it ahead of time. And I'm not up to date, but I believe it's not a settled discussion even in academia. The problem of continual consent is that if it must be continually given then you can never give your partner permission to initiate sex with you before you wake up, or agree that it's fine to have sex while drunk, and these are things a nontrivial amount of couples want and are not harmed by, which means such a rule is inadequate.

Re: Doctors investigate mystery brain disease in Canada

#305

Earlier quoted context omitted.

I do understand the concept. You have not changed my understanding with this description. If I am suffering a delusion, and you know that, then you know that I am not mentally competent. You know that, if I agree to something, I do not correctly understand what I am agreeing to. Any expression of consent you extract from me is invalid.

Yes, that’s why you’d get consent before hand

Consent beforehand doesn't bind or imply consent during the act. If you're saying consent beforehand counts, you're saying that it's not possible for anything to happen that would cause me to change my mind if I was in a mentally competent state.

Re: Doctors investigate mystery brain disease in Canada

#306

Earlier quoted context omitted.

I do understand the concept. You have not changed my understanding with this description. If I am suffering a delusion, and you know that, then you know that I am not mentally competent. You know that, if I agree to something, I do not correctly understand what I am agreeing to. Any expression of consent you extract from me is invalid.

This seems extreme. You are consenting to be deluded, knowing everything that will come afterwards. And the consenting during as well

But you don't know everything that will come afterwards. You know what's planned.

The consent during cannot be valid. It's not informed: in fact it's specifically misled, and that is known to the other participant.

Re: Doctors investigate mystery brain disease in Canada

#307
post #294

Earlier quoted context omitted.

What you are saying is dangerous. We had a serious set of exactly these transmission events in Britain only a few decades ago. Clearly the risk is not infinitesimal.

Dangerous? The hypothesized connection is not remotely clear. In vitro transformation of human PrP into PrP(Sc) by bovine PrP(Sc) is a necessary for the causal model. The fact that a strong species barrier exists, in vitro and in vivo, points towards a spurious association. It's understandable why one might infer from the correlation that there's a relationship but this is confounded by observation. The baseline expe…

What happened in the 1990s in Britain?

Re: Doctors investigate mystery brain disease in Canada

#308

Earlier quoted context omitted.

This seems extreme. You are consenting to be deluded, knowing everything that will come afterwards. And the consenting during as well

But you don't know everything that will come afterwards. You know what's planned. The consent during cannot be valid. It's not informed: in fact it's specifically misled, and that is known to the other participant.

So you are saying there is no way for two willing, informed adults to consent to this happening?

Re: Doctors investigate mystery brain disease in Canada

#309

Prion diseases terrify me. Especially having been in the UK eating beef at the time of the BSE outbreaks in the 1990s. I wonder if there have been studies on the scale of potential latent vCJD/Prion disease in the population?

Apparently the only options for diagnostic testing are brain biopsy and pulling CSF samples, both of which are probably a non-starter for screening purposes across a population.

Clinical Laboratory Tests Used To Aid in Diagnosis of Human Prion Disease Allyson Connor, Han Wang, Brian S. Appleby, Daniel D. Rhoads Journal of Clinical Microbiology Sep 2019, 57 (10) e00769-19; DOI: 10.1128/JCM.00769-19

https://jcm.asm.org/content/57/10/e00769-19

Re: Doctors investigate mystery brain disease in Canada

#310
post #173

Earlier quoted context omitted.

Are there many noteworthy modern science fiction authors that hold up to the Asimov / Clarke / Lem generation? I would think someone reasonably versed in science fiction would have at least heard of it -- I'm a "zoomer" and I have.

The actual writing from a lot of the golden age and New Wave sci-fi authors is... OK at best, with a few exceptions (Bradbury's distinctively poetic and dreamlike prose, for example). Tons of modern sci-fi authors write stories with more literary merit, better clarity, better-conveyed action, more believable characters and dialog, and so on. The improvements there are really obvious when reading, say, an early 70s Th…

> Whether their ideas and worlds stand up to Asimov and company, or happen to be appealing to a particular reader, is another matter, but the command of writing itself is overall better, I'd say.

But that's just the thing -- science fiction is about the ideas, and about the sociological and psychological impact of those ideas.

Whether a work has literary merit is neither here nor there for most people, and "science fiction" as a genre has been looked down upon by literary folks since it's inception. I don't know why anyone would be interested in praise from a community that is so invested in snobbery.

Regardless, science fiction authors of the time did have literary merit, if that's what you care about. LeGuin and Butler, are both regarded well in modern literary circles as far as I know. Vonnegut himself is regarded well also. At the time however, their books were condemned as being inadequate by the prevailing literary reviewers for various reasons unrelated to their actual writing.

Work from that time is perfectly functional and servicable for the most part, especially if you look at the places where the stories were submitted and published -- a small majority of Clarke's works ended up being published in Playboy, I don't think anyone can blame him for not creating a literary masterpiece when the majority of places that would actually pay him for his work were essentially pulp magazines.

Post reply on HN