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The origin of Covid: Did people or nature open Pandora’s box?

thebulletin.org

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Re: The origin of Covid: Did people or nature open Pandora’s box?

#161
Whatever the case turns out to be, i can’t help think of click and clack’s electric trailer brakes situation as i read the comment threads.

https://www.cartalk.com/radio/letter/andy-letter

Original section of the episode: https://www.cartalk.com/sites/default/files/bestmoments/2019...

Re: The origin of Covid: Did people or nature open Pandora’s box?

#162

If we apply Occam's razor [1] decision between "Wuhan, however, is home of the Wuhan Institute of Virology, a leading world center for research on coronaviruses" and "Wuhan, there is a wet market where under certain conditions virus can jump from bat to monkey to person" is relatively straightforward But then, we should probably also apply Hanlon's razor [2] "never attribute to malice that which is adequately explain…

I thought according to the crossover theory the virus was not theorised to have crossed from animal to person in the wet market, but was in humans already at that point and that was just the first “superspreader” site

Re: The origin of Covid: Did people or nature open Pandora’s box?

#163
post #157
post #146

Earlier quoted context omitted.

The natural origin hypothesis is also pushed for ideological reasons - at this level of meta analysis we are at a stalemate. The article was good at revealing that there is not just ideology - but also material interests involved and that the two prestigious letters that were so categorical in dismissing the lab escape hypothesis were quite a bit tainted by conflicts of interests.

I believe the lab origin theory is flawed based on the scientific reasoning, not the meta analysis. I agree that the meta analysis is inconclusive as it is not emphasising the science enough. The feeling I get is China doesn't really want to talk about it because it encourages ideologically motivated people to attack China, and serious scientists are mostly not convinced that this is a lab escape and so don't feel th…

The article is great at spelling a few things out, personally I feel enticed by it in some form. It is the job of other scientists to dispel any wrong or inaccurate information.

Usually the more interesting questions are of the kind of what -isn’t- being said, of what information isn’t being related or investigated.

Re: The origin of Covid: Did people or nature open Pandora’s box?

#164

If we apply Occam's razor [1] decision between "Wuhan, however, is home of the Wuhan Institute of Virology, a leading world center for research on coronaviruses" and "Wuhan, there is a wet market where under certain conditions virus can jump from bat to monkey to person" is relatively straightforward But then, we should probably also apply Hanlon's razor [2] "never attribute to malice that which is adequately explain…

Could also be God.

Re: The origin of Covid: Did people or nature open Pandora’s box?

#165

Earlier quoted context omitted.

So I've been pretty skeptical of the lab theory to date, but: > We visited the Wuhan Institute of Virology, which is an impressive research facility, and looks to be run well, with due regard to staff health. We spoke to the scientists there. We heard that scientists’ blood samples, which are routinely taken and stored, were tested for signs they had been infected. No evidence of antibodies to the coronavirus was fou…

I'm reading it as shorthand for, "The prior probability of a lab escape is low, and we didn't see much evidence for it in this particular case, therefore we conclude that this instance being a lab escape is low", which is a fine argument.

Yes.

It seems that proponents of the lab leak theory wants to turn the burden of proof upside down: I am claiming conspiracy starting with Anthony Fauci and ending up in a Chinese lab. It is up to you to provide hard evidence on why it is not so.

Sure you can do that as in freedom of thought and speech. But honestly; this is not really a constructive way to go about things.

Re: The origin of Covid: Did people or nature open Pandora’s box?

#166

We don't want to know. That may sound a bit glib but I think it's true. What would be the reaction if we could determine the outbreak was due to an unintentional leak? China cannot reimburse the world for the economic damage covid has caused. It cannot be held accountable for all the lives that have been lost. It cannot compensate the world for the diminished quality of life we've all suffered. But there will be plen…

Um, we could stop doing gain-of-function research for one. This would be a pretty important datapoint on that risk analysis.

I agree that gain-of-function research is very much playing with fire, but who is "we" that could stop doing gain-of-function research? The worst outcome, in my opinion, would be that all of the cautious ethical scientists stop doing gain-of-function research, organizations stop publishing safety guidelines because after all who needs safety guidelines when the research itself is illegal, and the only remaining people doing gain-of-function research are either irresponsible (grad student who doesn't know or doesn't care, and definitely doesn't have the equipment to do it safely) or nefarious (bioweapons research).

I see somewhat of a parallel with security research for computers -- you can try to ban it, and it will probably reduce the total research volume, but it will also decrease the level of openness and harm mitigation of the research that does remain.

Re: The origin of Covid: Did people or nature open Pandora’s box?

#167
post #122
post #66

There is an interesting peer reviewed paper published last month with analysis of existing facts about the origin of covid-19. A part from their conclusion: More than a year after the initial documented cases in Wuhan, the source of SARS-CoV-2 has yet to be identified, and the search for a direct or intermediate host in nature has been so far unsuccessful. The low binding affinity of SARS-CoV-2 to bat ACE2 studied to…

https://www.sciencedirect.com/science/article/pii/S187350612... Here is a paper that states that the furin cleavage site appears naturally in a number of viruses. I looked into these lab origin theories for the furin cleavage site last year. The problem with it being a laboratory insertion was that although performing an insertion is relatively easy once you know what to insert, generally it’s beyond current science…

> generally it’s beyond current science to independently create mutations for a specific purpose.

No it isn't.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810786/

Re: The origin of Covid: Did people or nature open Pandora’s box?

#168

For an alternative perspective on this - the official WHO report covers the lab hypothesis: https://www.who.int/health-topics/coronavirus/origins-of-the... Origins of the SARS-CoV-2 virus And unlike the arrticle here, this report is based upon interviews with employees at the lab and various form of documentation provided by the lab. Including health records of the employees. For more from one of the WHO people: http…

So I've been pretty skeptical of the lab theory to date, but: > We visited the Wuhan Institute of Virology, which is an impressive research facility, and looks to be run well, with due regard to staff health. We spoke to the scientists there. We heard that scientists’ blood samples, which are routinely taken and stored, were tested for signs they had been infected. No evidence of antibodies to the coronavirus was fou…

[deleted]

Re: The origin of Covid: Did people or nature open Pandora’s box?

#169
post #163
post #157

Earlier quoted context omitted.

I believe the lab origin theory is flawed based on the scientific reasoning, not the meta analysis. I agree that the meta analysis is inconclusive as it is not emphasising the science enough. The feeling I get is China doesn't really want to talk about it because it encourages ideologically motivated people to attack China, and serious scientists are mostly not convinced that this is a lab escape and so don't feel th…

The article is great at spelling a few things out, personally I feel enticed by it in some form. It is the job of other scientists to dispel any wrong or inaccurate information. Usually the more interesting questions are of the kind of what -isn’t- being said, of what information isn’t being related or investigated.

I agree it's enticing. I tend to agree with the scientist quoted that it's a conspiracy theory, but if it is then it's a really good one, and this article is well written.

If I'm right the reason it's not being analysed or investigated is that from a scientific perspective it's just not an interesting question, rather than for a deeper ideological reason as suggested in this article.

I drew the conclusion that this furin cleavage site theory wasn't actually convincing after a few days of wading through scientific literature, but as a non-expert I was pretty disappointed that there wasn't more accessible analysis of well-written arguments as presented in the article that would put it into a more objective perspective. It would have been great if that scientist they quote would have provided a more detailed rebuttal.

The problem is it actually isn't the job of scientists to dispel wrong or inaccurate information for the most part. They do detailed esoteric studies and write them up for specialists. It's nobody's job to rebut bad arguments, and that's the problem.

Re: The origin of Covid: Did people or nature open Pandora’s box?

#170
For me it felt allways a bit strange how fast china acted. The virus was very fresh, nothing was known, just a few cases and china totaly locked down millions if people. Two, three months later, when we already had high numbers if cases in the west, lockdowns started in the west also. But everybody said, "we know nothing about this new virus". For me it allways like, china knew much more about the virus early on.
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