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Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

nytimes.com

81–90 of 223 posts

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#81

Earlier quoted context omitted.

>Is this an education problem? Is there not a consistent minimum science curriculum for K-12 which covers pathogens, treatments and the history of vaccination programmes? Are there other factors that are relevant? I think it is more complicated than just education. The general sentiment I hear from people is in the past we were told that once we get vaccinated we could return to normal. Now we are told we still need…

>People are losing faith in the scientists because of their ever changing statements. I'd say this perfectly illustrates the complete lack of understanding of how science works among the public. There is never one specific stance that will always be right and hold up to all scrutiny. It's just highly intelligent educated experts giving their best possible estimate based on current data. As the data evolves, so do the…

I'd suggest reading some scientific papers before going too far in that direction. I've read a lot of them. These scientists routinely do things like cite papers that contradict the claim the citation is meant to support. They write papers based on circular logic. They conflate simulations with reality, they make claims that have no basis in biological science. They do not know what the false positive rate on COVID testing is, but are happy to draw conclusions that flatly contradict decades of biological understanding on the basis of data analysis that critically depends on knowing the correct value. They write models in C that are filled with memory corruption bugs and race conditions. When the results randomly change from run to run they claim that it's an experiment and so averaging the results makes it all perfectly fine. And when professional programmers tell them that incorporating memory corruption into their calculations is not fine, they assert those programmers don't understand science (see: https://github.com/mrc-ide/covid-sim/issues/165)

And that's just the scientists. Public health officials like Fauci have lied to the public and then admitted doing so, more than once! That isn't the data evolving, that's them deciding to change their story and explain that the previous one was a lie. What are we to make of such people?

You believe "experts know nothing" is insanity. I've read what those people are writing and am absolutely sure they know nothing, because if they did, they wouldn't keep engaging in these illegitimate, unscientific and desperately concerning practices.

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#82

my wife has a phd in drug development and is concerned about the speed in which this was released and the lack of long term safety trials. is she antivax/antiscience?

There were many technological advancement that allowed the release of the vaccine faster than ever. Often the long pole and vaccine development is the testing period. The thing is, when a non-trivial percentage of the population is actively infected, you can test really quickly. At this point the vaccines have made their way the tens or hundreds of millions of people, where the usual phase 3 clinical trial lasts a lo…

How would you test the potential long term effects of these new vaccines in an accelerated fashion?

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#83

my wife has a phd in drug development and is concerned about the speed in which this was released and the lack of long term safety trials. is she antivax/antiscience?

All the experts are concerned too. I work in vaccines (not claiming to be an expert) and I'm concerned too. Long-term safety trials take time, and so the question is how long are you willing to wait for the data? Its a shitty situation all around with the loss of human life, the impact to the economy and the politicization of every damn thing.

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#84

I'd love if someone broke down _reasons_ for vaccine hesitancy. It seems like the strategies we should develop for addressing them would be different, and that there shouldn't be a one-size-fits-all strategy, as we're trying to do today. So far, I personally have encountered the following viewpoints in my family and peer group (none of which I share) - in decreasing order of how much credence I'll give them: 1. I'm p…

How about: 5. I've already had COVID, and nothing thus far has indicated antibodies being that much less effective than a vaccine. If antibodies are claimed to wear off effectiveness, why wouldn't the vaccine just as much? Isn't the vaccine just an intentionally stimulated antibody response?

You are correct that there has not been time to do a thorough study of the differences between natural infection and the response to a vaccine. It is not crazy to want to wait a bit if you were recently infected.

However, there are good reasons to think that vaccines (particularly the mRNA-based ones) have a longer lasting protection than that a natural infection. They include only a very small part of the spike protein; with the booster, the force the body to create lots of targeted "memory" cells that are designed to last a long time. A natural infection may (i) target part of the virus that changes faster than the spike protein and (ii) without the booster effect, not produce as many memory B-cells.

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#85
I think this problem is more complex than many talk about and it ends up just being fear based news.

People aren't hesitant to get the vaccine because it might have Bill Gates microchips, they are hesitant because this was the fastest rolled out vaccine in human history (>3x faster than the second) and people don't trust the government. Their concerns aren't founded in science, but they are reasonable. So treating them as unreasonable is going to make them double down on their position. What's worse is that some news organizations ask similar questions but never answer (come on, you're the news and you can't google? WTF, no wonder people don't trust you). If you want to see the exaggerated version of this look at Russia where few trust the government and there is higher hesitancy to take Sputnik V.

Also we can't forget how the definition of herd immunity has changed. Back when the pandemic started I and many others warned that changing the definition of herd immunity to mean only herd immunity built through natural infection would empower anti-vaxers. Places like Nature[0] are supposed to be the place to get scientific news but botched this (even disagreeing with the experts they are quoting in the article), and they aren't the only one. This makes things rather confusing for people. This build distrust, and now we're seeing the repercussions of that. So when someone like Tucker Carlson goes on air and asks a bunch of questions and is always saying that the government wants you to "shut up and listen" (a common phrase) of course people question.

But these people will change, I've seen it. They have a bunch of questions but no answers, and like many, often don't know how to find them. This may be obvious to us who are so used to the internet and google daily to do our jobs, but these people don't even know how to do that or find credible sources. So it then comes down to us, the "smart people", to help. To talk about how doctors have been taking the vaccines for months before we got access. That politicians and wealthy white people wouldn't take it if it was an experiment. There's a lot of data to show that this isn't some grand experiment (well it is, but not in the way those people think experiments are. Maybe leave that nuance out?). But you have to do this without making the person feel like a fool. If you do this I promise they will soon change their minds. As for the 5G/Bill Gates people, well luckily they are a very small minority. Let's just not give them a platform. And don't equate vaccine hesitancy for that. It will just make the path to herd immunity more difficult.

[0] https://www.nature.com/articles/d41586-020-02948-4

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#86
post #72

Earlier quoted context omitted.

Information about the virus and the virus itself has changed since last summer. One adjusts approaches based on changing data. Being flexible is a positive trait.

Indeed. Leadership has been the _opposite_ of flexible. They stubbornly hold on to talking points and policies.

I don't think the story is an example of conflicting messages though. Different messages at different times based on new data, but not at a single point in time.

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#87

I wanted to add that a lot of the people I know who are “vaccine hesitant” are just waiting a little longer to see how things go. I don’t see a whole lot of representation of folks who intend to get the vaccine this summer when I read publications and articles about it, but I would wager that there’s more people intending to get it but not quite yet than we think.

France here, I’m just waiting for the end of the state of emergency + two months. I’ll vaccinate when the press is free to discuss the problems (and does it). I estimate we can’t know the truth about vaccines as long as the press is mandated by law to say what the president mandates them to say, and there is no reason to trust a president who holds his “conseil des ministres” in a bunker (“conseil de défense sanitair…

Wow - I did not know that was the case.

Look - I'm pretty pro-vax, I went and paid for a bunch privately a couple of years ago because I was travelling and thought 'why not get them all?' (like going for the nice-fancy-extra car wash program), and always get the flu shot - but that, wow, sounds frankly outrageous.

[EDIT] As a Brit in Europe - I do sometimes get the feeling that a lot of this is political maneuvering managing the fallout from the EU's less than stellar program (people can debate all they like, but the objective facts are: They tried, for the first time, to procure vaccines centrally, and after the same amount of time, demographics in the UK and US have them that don't in the EU), so maybe that's why they're so protective about it.

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#88

Earlier quoted context omitted.

>Is this an education problem? Is there not a consistent minimum science curriculum for K-12 which covers pathogens, treatments and the history of vaccination programmes? Are there other factors that are relevant? I think it is more complicated than just education. The general sentiment I hear from people is in the past we were told that once we get vaccinated we could return to normal. Now we are told we still need…

>People are losing faith in the scientists because of their ever changing statements. I'd say this perfectly illustrates the complete lack of understanding of how science works among the public. There is never one specific stance that will always be right and hold up to all scrutiny. It's just highly intelligent educated experts giving their best possible estimate based on current data. As the data evolves, so do the…

[deleted]

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#89
post #50

Earlier quoted context omitted.

I don't think it was "institution skeptics" who made COVID a political issue. How many months did it take before academics were claiming that anti-lockdown protests were dangerous and must not happen but BLM protests were to be encouraged, because "systemic racism" is a public health issue? Not many. How many other academics condemned this blatant politicization of science? Not enough. Lockdowns don't work: US states…

Lockdown worked fine in New Zealand it not? The thing is, it’s something you have to commit to. You can’t just half ass it.

You realize they achieved this by effectively locking down their borders right? Now, imagine the response if Trump had suggested this. Actually, you don't even need to imagine it:

https://www.huffpost.com/entry/trump-coronavirus-borders_n_5...

Re: Reaching ‘Herd Immunity’ from Covid Is Unlikely in the U.S., Experts Now Believe

#90

my wife has a phd in drug development and is concerned about the speed in which this was released and the lack of long term safety trials. is she antivax/antiscience?

There were many technological advancement that allowed the release of the vaccine faster than ever. Often the long pole and vaccine development is the testing period. The thing is, when a non-trivial percentage of the population is actively infected, you can test really quickly. At this point the vaccines have made their way the tens or hundreds of millions of people, where the usual phase 3 clinical trial lasts a lo…

We don't know what the long term effects of either the virus or the vaccine are on a human. Hell we can't possibly even have data on what the long term effects are on humans. It doesn't matter how many people have been exposed.
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