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Brazil Rejects the Gamaleya Vaccine
21–30 of 124 posts
Re: Brazil Rejects the Gamaleya Vaccine
#22The respone from Gamaleya: https://sputnikvaccine.com/newsroom/pressreleases/sputnik-v-...
To me Gamaleya is turning a thecnical decision in a political one. Thanks to mistakes and possible crimes commit by the Brazilian goverment, when rejecting other vacines, they are now being pressured in accepting this vaccine no matter what. I don't think this is how a sanitary inspection agency should act, approving things based in pure pressure.
Re: Brazil Rejects the Gamaleya Vaccine
#23A reminder that "U.S. officials pushed Brazil to reject Russia’s coronavirus vaccine" [0] for political reasons. > Under a section titled “Combating malign influences in the Americas,” the HHS report states that countries including Russia “are working to increase their influence in the region to the detriment of US safety and security.” The global affairs office coordinated with other U.S. government agencies “to dis…
Further, Sputnik V is the most effective (91.4%), non-mRNA vaccine. Therefore the best vaccine to take to minimise personal risk.
US officials are doing Brazilians no favor.
Re: Brazil Rejects the Gamaleya Vaccine
#24I wonder how much we are seeing general problems with adenovirus vector vaccines (e.g. blood clotting and this manufacturing issue) only because we've never rolled a vaccine out to a large population so quickly. Regulatory agencies are likely afraid to approve any at this point, which does not bode well for other vaccines using the same technology.
Intuitively speaking, using a viral vector has inherent risks that aren’t present with mRNA or protein subunit vaccines. To the extent that the latter technologies prove effective for vaccines against various viruses, I would think viral vectors should not be a preferred technology going forward for vaccine development.
Intuitively, the risks of viral vector vaccines are well known because they have been used for at least a decade while mRNA are being used in large scale for the first time only now.
Re: Brazil Rejects the Gamaleya Vaccine
#25I wonder how much we are seeing general problems with adenovirus vector vaccines (e.g. blood clotting and this manufacturing issue) only because we've never rolled a vaccine out to a large population so quickly. Regulatory agencies are likely afraid to approve any at this point, which does not bode well for other vaccines using the same technology.
I am not a virologist, but blood clotting might be related to the specific payload rather than the platform. The original SARS-CoV2 has the same property. Could it be related to the spike protein?
Re: Brazil Rejects the Gamaleya Vaccine
#26A reminder that "U.S. officials pushed Brazil to reject Russia’s coronavirus vaccine" [0] for political reasons. > Under a section titled “Combating malign influences in the Americas,” the HHS report states that countries including Russia “are working to increase their influence in the region to the detriment of US safety and security.” The global affairs office coordinated with other U.S. government agencies “to dis…
Further, Sputnik V is the most effective (91.4%), non-mRNA vaccine. Therefore the best vaccine to take to minimise personal risk. US officials are doing Brazilians no favor.
The problem if the vacine was not the efficiency. It was rejected based on poor documentation, and quality control. Both serious problems that need to be solved before approval in any serous regulatory agency.
Re: Brazil Rejects the Gamaleya Vaccine
#27A reminder that "U.S. officials pushed Brazil to reject Russia’s coronavirus vaccine" [0] for political reasons. > Under a section titled “Combating malign influences in the Americas,” the HHS report states that countries including Russia “are working to increase their influence in the region to the detriment of US safety and security.” The global affairs office coordinated with other U.S. government agencies “to dis…
Further, Sputnik V is the most effective (91.4%), non-mRNA vaccine. Therefore the best vaccine to take to minimise personal risk. US officials are doing Brazilians no favor.
Ignoring your efficacy claims, the linked article indicates that the vaccine being distributed now is likely not the same as the one that was used in clinical trials.
In particular,
> Anvisa, the Brazilian drug agency, said that every single lot of the Ad5 Gamaleya shot that they have data on appears to still have replication-competent adenovirus in it.
This is a serious issue because none of the virus vector is supposed to be competent to replicate. Something is very clearly wrong with the vaccine that's being distributed.
It's not the Americans.
Re: Brazil Rejects the Gamaleya Vaccine
#28A reminder that "U.S. officials pushed Brazil to reject Russia’s coronavirus vaccine" [0] for political reasons. > Under a section titled “Combating malign influences in the Americas,” the HHS report states that countries including Russia “are working to increase their influence in the region to the detriment of US safety and security.” The global affairs office coordinated with other U.S. government agencies “to dis…
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Re: Brazil Rejects the Gamaleya Vaccine
#29A reminder that "U.S. officials pushed Brazil to reject Russia’s coronavirus vaccine" [0] for political reasons. > Under a section titled “Combating malign influences in the Americas,” the HHS report states that countries including Russia “are working to increase their influence in the region to the detriment of US safety and security.” The global affairs office coordinated with other U.S. government agencies “to dis…
Here's a follow-up post on the behavior by the Sputnik V Twitter account https://blogs.sciencemag.org/pipeline/archives/2021/04/28/ru...
Greg Lowe is a very respected commentator on all things vaccines.
Re: Brazil Rejects the Gamaleya Vaccine
#30Virologist Dr. Angela Rasmussen about the ability of the vector virus to replicate
https://mobile.twitter.com/angie_rasmussen/status/1387397186...