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CDC panel recommends resuming use of Johnson and Johnson vaccine

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Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#201

Post by dragonwriter »

refurb wrote: post #200
dragonwriter wrote: post #187

Earlier quoted context omitted.

The US has no pending decision on AZ; AZ hasn’t applied for any kind of approval in the US, and officials have indicated that they hope AZ doesn't.

“The company's early April timeline has passed, but a spokesman on Wednesday said the company is still "progressing submission to the FDA." https://www.fiercepharma.com/pharma/astrazeneca-still-plans-... Likely not much demand but a positive FDA decision can boost confidence in other markets.

From your own sourcd, emphasis added:

“but AstraZeneca is still planning to apply for emergency use authorization of its shot in the U.S.”

planning to = has not

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#202

Post by ulfw »

mssundaram wrote: post #127
ggm wrote: post #106

Earlier quoted context omitted.

Kind of untested: sorry that's just wrong. All these shots are tested by 40,000 or more people. The problems emerging now are in the one in 100,000 or more. Do the maths on the odds.

Compared to other vaccines, 40,000 is "kinda untested"

The f other vaccines had more than 40,000 trial participants. Please list them all. You seem to think there are so many.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#203

Post by refurb »

dragonwriter wrote: post #201
refurb wrote: post #200

Earlier quoted context omitted.

“The company's early April timeline has passed, but a spokesman on Wednesday said the company is still "progressing submission to the FDA." https://www.fiercepharma.com/pharma/astrazeneca-still-plans-... Likely not much demand but a positive FDA decision can boost confidence in other markets.

From your own sourcd, emphasis added: “but AstraZeneca is still planning to apply for emergency use authorization of its shot in the U.S.” planning to = has not

That’s because you don’t apply until you have your whole data package. There is no “apply as step 1” it’s “you submit your application when it’s complete”.

https://www.fda.gov/media/97321/download#page13

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#204

Post by jonplackett »

caddemon wrote: post #174
jonplackett wrote: post #137

Earlier quoted context omitted.

It's a good point - I don't know enough about the J+J one to comment on that, this was based on the AZ vaccine. Do you know if anyone has died from the J+J one? Because that's what I am comparing with for the AZ one, so it's actually in that sense less risky that AZ anyway.

The link above states 3 women so far have died from J&J and 7 more remain hospitalized. If you do demographic-specific division and compare that to the likelihood that same demographic would die from COVID, it seems unclear to me that young women would come out better getting the J&J vaccine. Both things are very unlikely to happen, but ultimately it's easy to get a Pfizer or Moderna appointment these days (at least…

I’m here in the UK and we have limited supply of anything but he AZ vaccine which we make here, so it’s a slightly different story. We can’t choose what jab we get. You just get an appointment and get whatever you get when you arrive.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#205

Post by ergocoder »

void_mint wrote: post #37
sjm wrote: post #5

Just makes sense. The benefits far outweigh the risks at six cases of blood clots out of over 6.8 million doses, especially when there's a high risk of blood clots following COVID-19 hospitalization. Not to mention rates of blood clots caused by the pill are more like 1 in 3000. Hopefully if anything the pause has shown anti-vax folks that the safety of these vaccines is being taken seriously.

> Hopefully if anything the pause has shown anti-vax folks that the safety of these vaccines is being taken seriously. The anti vaxx community is uninterested in science. This won't change anything.

Pause or not pause. Anti-vaxx will never be convinced. In whatever way, they will come up with new excuses.

I care about whether the vaccine is safe. I would be seriously concern if officials take anti-vaxx into consideration.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#206

Post by wincy »

hcurtiss wrote: post #89
grej wrote: post #21

Both my wife and I got the J&J shot before it was cancelled. We both had a period about 12 hours afterwards where we felt like we had a mild flu for about another 12 hours, then it was over and we’ve felt fine. Very happy with this decision.

If we're doing anecdata, I too had the J&J shot right before it was cancelled. Literally no symptoms whatsoever. Very happy with the "one and done" relative to my wife who will go in next week for the second Pfizer shot, which has clobbered everyone else in our neighborhood who took it.

My anecdata, I got the J&J shot the Monday before it was cancelled. Went to sleep shivering that night. Felt better the next day, then terrible the day after that, then had an earth shattering headache like a bomb went off in my head the next day after that. Went to the ER at my wife’s insistence that they did a CT scan with the dye and all that. Said everything looks fine. I wasn’t having headaches before this but who knows maybe it’s just a coincidence. Sure seems like I’m getting a lot more headaches in the last couple weeks though.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#207

Post by ithkuil »

ipaddr wrote: post #161
ggm wrote: post #103

Earlier quoted context omitted.

Africa or India or south America need them more than G8 economies

India produces their own version locally. South Africa has unapproved J&J and AstrV. Central America could use some. Brazil doesn't have a lacking issue, the big issue is they can't get people to take the second dose.

> can't get people to take the second dose.

What is the reason? People don't bother? Are afraid? Organizational issues?

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#208

Post by williamtwild »

ulfw wrote: post #202
mssundaram wrote: post #127

Earlier quoted context omitted.

Compared to other vaccines, 40,000 is "kinda untested"

The f other vaccines had more than 40,000 trial participants. Please list them all. You seem to think there are so many.

In general terms : Flu , shingles for starters

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#209

Post by ulfw »

williamtwild wrote: post #208
ulfw wrote: post #202

Earlier quoted context omitted.

The f other vaccines had more than 40,000 trial participants. Please list them all. You seem to think there are so many.

In general terms : Flu , shingles for starters

Flu vaccine Phase 3 trials with over 40,000 participants? I couldn't find one. Most are in the 15K range.

As is the latest shingles vaccine trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590925/

(14,759 patients who received two doses of HZ/su (n = 7,344) or placebo (n = 7,415))

So if 40,000 is "kinda untested" than this one must be complete and utter made-up then

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#210

Post by dragonwriter »

refurb wrote: post #203
dragonwriter wrote: post #201

Earlier quoted context omitted.

From your own sourcd, emphasis added: “but AstraZeneca is still planning to apply for emergency use authorization of its shot in the U.S.” planning to = has not

That’s because you don’t apply until you have your whole data package. There is no “apply as step 1” it’s “you submit your application when it’s complete”. https://www.fda.gov/media/97321/download#page13

My point is the US doesn’t have a “pending decision” on AstraZeneca, the US has the potential (uncertain for many reasons) that they might apply at some time in the future.

Of course, AZ also lost its production capacity even if it was going to be approved, since it was dependent on the troubled Emergent facility which has been taken over but J&J and dedicated exclusively tonthe J&J vaccine, and has not located new production facilities.

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