Live data from Hacker News

CDC panel recommends resuming use of Johnson and Johnson vaccine

axios.com

141–150 of 232 posts

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#141
post #77

I had Covid in March 2020. It almost did me in. Was in ICU for a while. Had the J&J shot three weeks ago. Did not feel a thing. My arm was slightly sore at injection site. Nothing else. I guess my body was used to it and just sort of shrugged it off. Some of my friends who got J&J were sick for a few days, but rebounded quickly after that.

Usually previous covid infection will make vaccine reactions worse not better. (due to an increased immune reaction)

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#142

Earlier quoted context omitted.

The studies have only gone on for, at most, 8 months. So for every time period studied so far, including the longest possible time periods, people retain immunity. Perhaps use this science to revise your initial belief/statement.

While I mostly agree, there have been a few rare cases of reinfection; here [0] is a metastudy that looks at several claims of reinfection, ultimately concluding that 6 cases were credible reinfections. So while the relative risk is very low, I think one could make a plausible argument that since the risk of harmful side effects is also low, getting vaccinated may be beneficial. There is also preliminary evidence [1]…

6 cases of reinfection out of millions of cases of covid still has contracting covid granting much better immunity than the vaccine.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#143
post #74
post #44

Earlier quoted context omitted.

Personally, I prefer drug safety protocols be based on science, not what people feel, or whether or not it's "good politics".

> Personally, I prefer drug safety protocols be based on science, not what people feel, or whether or not it's "good politics". Implicit to this point is that what the CDC/FDA did was "good science" and not bad science.

No, implicit to the point is that what the CDC/FDA did was follow the ongoing drug safety monitoring protocols that have long been established for Emergency Use Authorization.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#144
post #94

Earlier quoted context omitted.

If we're doing anecdata, I too had the J&J shot right before it was cancelled. Literally no symptoms whatsoever. Very happy with the "one and done" relative to my wife who will go in next week for the second Pfizer shot, which has clobbered everyone else in our neighborhood who took it.

My anecdote is that I got the JJ and kinda regret it, this blood clot thing made me realize it’s pretty untested , I feel like they should be recommending everyone get a full panel blood test a week after to add more data. After the AZ issues there should have been more scrutiny of the early clot cases

The average risk of thrombosis the J&J and AstraZeneca vaccine have are between 1 in 100,000 to 1 in 250,000. To put some perspective, estrogen-based medication like the contraceptive pill have a risk of 1 in 1,000.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#145
post #129
post #106

Earlier quoted context omitted.

Kind of untested: sorry that's just wrong. All these shots are tested by 40,000 or more people. The problems emerging now are in the one in 100,000 or more. Do the maths on the odds.

It's obviously not well tested enough to not get pulled out of use despite the pandemic, so more testing as we move forward seems appropriate. OP has a point, although the form of testing will probably be one less likely to cause people to avoid the vaccine. Also, what are the odds of a 1 in 10k concern not being picked up as such in a 40k sample size? It would look like background noise if it was only one case in th…

Its not 1 in 10k. You're overstating the risk. It's because its not 1 in 10k it was only picked up after mass vaccination began.

See? you're inflating risk and misunderstanding consequences. How many people die, if nobody is vaccinated compared to a 1 in 100,000 risk of clotting? A lot more than 1 in 100,000 die from covid.

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#146
post #106

Earlier quoted context omitted.

Kind of untested: sorry that's just wrong. All these shots are tested by 40,000 or more people. The problems emerging now are in the one in 100,000 or more. Do the maths on the odds.

Compared to other vaccines, 40,000 is "kinda untested"

During a pandemic?

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#147

Earlier quoted context omitted.

While I mostly agree, there have been a few rare cases of reinfection; here [0] is a metastudy that looks at several claims of reinfection, ultimately concluding that 6 cases were credible reinfections. So while the relative risk is very low, I think one could make a plausible argument that since the risk of harmful side effects is also low, getting vaccinated may be beneficial. There is also preliminary evidence [1]…

6 cases of reinfection out of millions of cases of covid still has contracting covid granting much better immunity than the vaccine.

6? lol. The number is 70 with 36,000+ suspected. https://bnonews.com/index.php/2020/08/covid-19-reinfection-t...

Vaccine-based immunity allows for a greater variance in neutralizing antibodies to form relative to the spike protein, compared to natural immunity attacking less critical vectors. Get the vaccine even if you had covid

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#148
post #132

Earlier quoted context omitted.

> we should send them to another country like Canada or Mexico I'm under the impression that the US has been sending its AZ doses to Canada and Mexico since mid-March: https://www.theguardian.com/world/2021/mar/18/us-astrazeneca...

That was one time, and those vaccines were on the cusp of expiring. https://globalnews.ca/news/7728936/astrazeneca-vaccine-doses...

Biden has indicated that the Americans intend to continue supplying doses to Canada. Perhaps Mexico too. https://globalnews.ca/news/7777450/biden-covid-vaccine-canad...

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#149

Now maybe the US can finally approve the AstraZeneca vaccine and put our 20 million (!) doses on hand to good use. Or not! But if we’re not going to use them, we should send them to another country like Canada or Mexico or Australia or the UK or EU, all of which have approved it and administered millions of doses. Sitting on 10s of millions of vaccines during a pandemic is inexcusable.

Alas, a lot of that supposed AZ stockpile traces back to the troubled Emergent Biosolutions facility. I don't think it had FDA certification when it produced them.

Exactly zero of the J&J doses from that facility have been given to Americans. 15M J&J doses were discarded because they were contaminated with AZ ingredients. Tens of millions more are currently in quarantine awaiting other evaluations & may never be used. The facility has halted production & there are some hints it may not restart.

Some of the AZ already sent to Canada was from that plant, made under conditions that that can now only be verified imperfectly in retrospect, based on the kind of incomplete records the company has been in trouble for.

https://nationalpost.com/news/canada/more-than-half-canadas-...

Re: CDC panel recommends resuming use of Johnson and Johnson vaccine

#150
post #99
post #77

I had Covid in March 2020. It almost did me in. Was in ICU for a while. Had the J&J shot three weeks ago. Did not feel a thing. My arm was slightly sore at injection site. Nothing else. I guess my body was used to it and just sort of shrugged it off. Some of my friends who got J&J were sick for a few days, but rebounded quickly after that.

What prompted you to get a vaccine when you have already developed immunity?

I'm in a similar situation - COVID-19 resulting in an ICU stay, then the vaccine (Oxford-AZ) - and I figured it couldn't hurt (read: was extremely unlikely to cause major side effects) and _may_ confer some slight benefit (similar to mixing vaccines or just renewing my immunity). Vaccine passports were also being mulled around that point, and I assumed it would make that process easier if necessary.

In the end, I did get some side effects, but nothing long term - a hard, hot to the touch, red circle of about 4" diameter formed around the injection site, and I could barely move my arm away from my body without significant pain, both for about a week.

Post reply on HN