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Association of sleep duration in middle and old age with incidence of dementia

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Re: Association of sleep duration in middle and old age with incidence of dementia

#121
post #105

Earlier quoted context omitted.

https://pubmed.ncbi.nlm.nih.gov/20182054/#:~:text=In%20the%2... . this says coffee is associated with a reduced risk of dementia which is pretty much what I've read over and over again

Thank you! I was freaking out about my beloved coffee addiction.

Never blame the coffee.

Re: Association of sleep duration in middle and old age with incidence of dementia

#122

Earlier quoted context omitted.

He's leaning hard into the stimulants...

People with amphetamine habits typically look very skinny and unhealthy because amphetamines suppress appetite. Same for cocaine, ritalin and all other dopaminergic stimulants. They can also have facial scabs because of obsessive picking/scratching, and tend to be very twitchy and hyper. He doesn't come off that way at all during interviews. My personal experience leads me to believe that there is no way Elon Musk co…

I know - quite literally - at least a dozen people who take amphetamines daily and display few or none of the visible descriptions you list above. None of us know what EM ingests.

Re: Association of sleep duration in middle and old age with incidence of dementia

#123
post #93

Earlier quoted context omitted.

Coffee causing dementia is a pretty shocking claim that I haven't heard previously. Do you have more reading on this?

I've always wondered if coffee studies are just something they give bored grad students to do. I've heard about what seems like hundreds of them in my lifetime and they contradict each other in cycles over long stretches of time.

Same! One week it’s terrible for you. The next week it’s curing cancer. I just try not to have any past a certain hour so as to not interrupt my sleep.

Re: Association of sleep duration in middle and old age with incidence of dementia

#124

Many forms of dementia destroy dopaminergic neurons, and this process begins much earlier than symptoms of dementia itself manifest. From what I’ve gathered from reading studies across the years, less dopaminergic capacity seems to be associated with less restful sleep. The conclusions of this study seem to have it backwards. It’s not lack of sleep that causes dementia, it’s early dementia that causes insomnia. Edit:…

> it’s early dementia that causes insomnia > If they drink too much coffee, they might accidentally poison themselves into dementia Oh crap

I wouldn't take anyone making a comment on HN a source of accurate and truthful data. The HN bias can be at play. Which is the bias that we believe and trust a random comment on Hacker News more than a linked research study, or the body of experts around a subject (who don't comment on Hacker News).

Re: Association of sleep duration in middle and old age with incidence of dementia

#125

Many forms of dementia destroy dopaminergic neurons, and this process begins much earlier than symptoms of dementia itself manifest. From what I’ve gathered from reading studies across the years, less dopaminergic capacity seems to be associated with less restful sleep. The conclusions of this study seem to have it backwards. It’s not lack of sleep that causes dementia, it’s early dementia that causes insomnia. Edit:…

Please don’t upvote this nonsense. Harmala alkaloids are found in tobacco, not coffee.

Re: Association of sleep duration in middle and old age with incidence of dementia

#127
post #11

More accurately, middle aged people who get less than 6 hours of sleep a night are 30% more likely to get dementia. I'd expect that people who get less than 6 hours of sleep are also more stressed and less health concious though.

That's not more accurately at all; you're still insinuating a causal relationship. "More accurately, people with yellow-stained fingertips are more likely to get lung cancer." The actual study's own title puts it more accurately: "Association of sleep duration in middle and old age with incidence of dementia"

I don't think it insinuates a causal relationship.

I interpret "30% more likely" as the same as "associated with a 30% increase," which is what the article claims.

Re: Association of sleep duration in middle and old age with incidence of dementia

#128

Many forms of dementia destroy dopaminergic neurons, and this process begins much earlier than symptoms of dementia itself manifest. From what I’ve gathered from reading studies across the years, less dopaminergic capacity seems to be associated with less restful sleep. The conclusions of this study seem to have it backwards. It’s not lack of sleep that causes dementia, it’s early dementia that causes insomnia. Edit:…

In fairness to the study, it's only claiming an association, not a causal link.

Re: Association of sleep duration in middle and old age with incidence of dementia

#129
post #7

Unless it's an emergency, I've ALWAYS prioritized sleep. It's just too important for health regardless of these latest findings. I'd call in to work if I didn't get a full nights rest in the past, it's not worth feeling like shit for the rest of the day. The culture of glamorizing working longer and harder till early hours of the mornings on zero sleep, has always been nonsense. Musk is notorious for bragging about t…

I wonder if Elon Musk has the "short sleep" genes?

https://www.ucsf.edu/news/2019/08/415261/after-10-year-searc...

Re: Association of sleep duration in middle and old age with incidence of dementia

#130
post #7

Unless it's an emergency, I've ALWAYS prioritized sleep. It's just too important for health regardless of these latest findings. I'd call in to work if I didn't get a full nights rest in the past, it's not worth feeling like shit for the rest of the day. The culture of glamorizing working longer and harder till early hours of the mornings on zero sleep, has always been nonsense. Musk is notorious for bragging about t…

Well, many people don't sleep enough because they cannot. Insomnia is common in midlife.

Most cases of insomnia in midlife are caused by lifestyle problems: lack of exercise, substance abuse, and obesity-induced apnea.
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