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Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

pubmed.ncbi.nlm.nih.gov

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Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#71

Post by andy_ppp »

rsync wrote: post #59
legerdemain wrote: post #7

Earlier quoted context omitted.

Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism."

"Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism."" Everything you have said is true. What I think you are missing is that…

Yes, also we know cell machinery operates in a different mode when the body is without fuel, it’s moves in a repair/conserve mode that includes preferential autophagy of damaged cells. It makes sense, eating used to be extremely dangerous so the body mounts an immune response including inflammation every time.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#72

Post by jader201 »

sparrc wrote: post #26

It's always strange to me how certain studies seem to gain so many upvotes on hackernews....a few thoughts: 1. This is a single study published in 2015, what does the wider literature say? Any dieticians or clinicians recommending anything from this? 2. The journal is EBioMedicine, which is not nothing but not exactly pre-eminent either. 3. This seems like just a common sense conclusion: "In Cox proportional hazard m…

I think you’re overthinking it.

Certain studies gain so many upvotes on HN because they generate interesting discussion, and may be worth storing in our favorites for sharing and/or future reference.

I almost always upvote articles when there is interesting discussion (or the potential for interesting discussion) related to the article. I very rarely (but do sometimes) upvote articles solely based on the content of the articles themselves.

Or rather, I’m much more interested in a collection of people’s thoughts vs. a single person’s thoughts.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#73

Post by Robotbeat »

BurningFrog wrote: post #61
sparrc wrote: post #26

It's always strange to me how certain studies seem to gain so many upvotes on hackernews....a few thoughts: 1. This is a single study published in 2015, what does the wider literature say? Any dieticians or clinicians recommending anything from this? 2. The journal is EBioMedicine, which is not nothing but not exactly pre-eminent either. 3. This seems like just a common sense conclusion: "In Cox proportional hazard m…

Outside of physics, a single study with a surprising result is usually wrong.

Even in physics...

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#74

Post by raducu »

thatcat wrote: post #62
andreygrehov wrote: post #38

Earlier quoted context omitted.

Curious – are there legitimate ways to measure stress?

only short term via cortisol, long term burnout is as mysterious as it is destructive

I guess I'll check it out.

I'm 37 and I think my room started having the old person smell.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#75

Post by moneywoes »

kossTKR wrote: post #8
TimSchumann wrote: post #3

Anecdote, but this may explain why I feel so much healthier when I'm fasting regularly. Turns out, if you stop putting everything but water/salt in your body, there's not much left that causes inflammation.

Same here. It's the closest thing to an actual wonder drug i have ever come across. My skin clears up, brainfog disappears, the white in my eyes get brighter, etc. After reading a bit i have come to the same conclusion - if your diet is already extremely clean / bland, maybe you won't get the same effect, but for most people that eats lots of different foods, processed stuff, fast food, alcohol, harsh additives, frie…

Is there any science behind it? Anecdotally I notice the same things especially with my skin CL earning up.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#76

Post by andy_ppp »

atat7024 wrote: post #16
legerdemain wrote: post #7

Earlier quoted context omitted.

Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism."

Every time you eat, the body enters a state of heightened inflammation. This is well documented. Please don't spread disinformation.

https://www.sciencedaily.com/releases/2017/01/170116121912.h... For example suggests this is true...

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#77

Post by andy_ppp »

darkteflon wrote: post #25
atat7024 wrote: post #16

Earlier quoted context omitted.

Every time you eat, the body enters a state of heightened inflammation. This is well documented. Please don't spread disinformation.

Pseudoscience schooling science.

No, please do some research, even a cursory Google leads to many papers on this.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#78

Post by raducu »

koolba wrote: post #50
andreygrehov wrote: post #38

Earlier quoted context omitted.

Curious – are there legitimate ways to measure stress?

You could count the amount of hair loss or lack thereof. I bet hours of nightly REM sleep would be inversely correlated as well.

I have terrible sleep, but my hours of REM sleep are fine.

It's my deep sleep that's toast; also I get to the REM stage too quickly, I think it's supposed to be a sign of depression.

So it's a bit more complicated.

Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age

#79

Post by andy_ppp »

legerdemain wrote: post #7
TimSchumann wrote: post #3

Anecdote, but this may explain why I feel so much healthier when I'm fasting regularly. Turns out, if you stop putting everything but water/salt in your body, there's not much left that causes inflammation.

Inflammation is a basic life process, not a reaction to the food you eat. Inflammation plays an active part in wound-healing. Teething in infants has an inflammatory component. Systemic inflammation is ubiquitous during and following parturition in mammals. There is inflammation everywhere, it's as generic a word as "oxidation" and "metabolism."

No-one is say all inflammation is bad, just that constantly being in that state is really bad for you...
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