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Psilocybin 'promising' for depression

bbc.co.uk

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Re: Psilocybin 'promising' for depression

#151

Post by jokoon »

pbadenski wrote: post #99
internetslave wrote: post #8

Earlier quoted context omitted.

I know a lot of people whose minds were ruined by psychedelics. It’s something you will see when you spend time in those communities. It doesn’t happen to everyone, but it’s common.

This type of empty fear mongering comment is unhelpful at best. It's a McDonalds of a comment. What's a lot of people? Why are psychedelics so special compared to anything else (sugar, Facebook, gambling). "It doesn't happen to everyone, but it's common" - what does this even mean? "Common" based on what criterion? How should our behaviour as a society change based on your comment?

Are you comparing psychedelics to sugar and social media?

Unless psilocybin is thoroughly tested and validated as a treatment that is as safe as SSRI, I don't think it's really worthwhile to jump into the psilocybin train.

Re: Psilocybin 'promising' for depression

#152

Post by singingfish »

jokoon wrote: post #151
pbadenski wrote: post #99

Earlier quoted context omitted.

This type of empty fear mongering comment is unhelpful at best. It's a McDonalds of a comment. What's a lot of people? Why are psychedelics so special compared to anything else (sugar, Facebook, gambling). "It doesn't happen to everyone, but it's common" - what does this even mean? "Common" based on what criterion? How should our behaviour as a society change based on your comment?

Are you comparing psychedelics to sugar and social media? Unless psilocybin is thoroughly tested and validated as a treatment that is as safe as SSRI, I don't think it's really worthwhile to jump into the psilocybin train.

SSRI's can be not terribly safe as well. In some people their use leads to extremely unsafe impulsive behaviour and which itself can lead to suicide.

Re: Psilocybin 'promising' for depression

#153

Post by spoiler »

spoiler wrote: post #84
acchow wrote: post #50

Earlier quoted context omitted.

In what way were their minds ruined?

Not OP, but there can be a few things they're alluring to. Some disassociatives are often put into the "psychedelic," and they can cause addiction. Ketamine begin an example. People begin chasing the previous high, which often means higher doses and more money. Some more ignorant people put MDMA (and family) of drugs into this category as well. These drugs are highly neurotoxic, and require a lot of "prep" to take to…

Off-topic: writing long form text on a phone is such a chore. I can't edit the typos anymore, but just to clarify: "Aimee" was meant to be "mostly they". There's also a few words dropped here and there, but it doesn't impact readability as much.

Re: Psilocybin 'promising' for depression

#154

Post by theshrike79 »

jokoon wrote: post #151
pbadenski wrote: post #99

Earlier quoted context omitted.

This type of empty fear mongering comment is unhelpful at best. It's a McDonalds of a comment. What's a lot of people? Why are psychedelics so special compared to anything else (sugar, Facebook, gambling). "It doesn't happen to everyone, but it's common" - what does this even mean? "Common" based on what criterion? How should our behaviour as a society change based on your comment?

Are you comparing psychedelics to sugar and social media? Unless psilocybin is thoroughly tested and validated as a treatment that is as safe as SSRI, I don't think it's really worthwhile to jump into the psilocybin train.

Yeaaa, SSRI isn't safe by any means.

It won't kill you for sure. But a 100% loss in sex drive isn't really something people actually want. Took a year after stopping SSRIs to get back.

Re: Psilocybin 'promising' for depression

#155

Post by boloust »

jokoon wrote: post #151
pbadenski wrote: post #99

Earlier quoted context omitted.

This type of empty fear mongering comment is unhelpful at best. It's a McDonalds of a comment. What's a lot of people? Why are psychedelics so special compared to anything else (sugar, Facebook, gambling). "It doesn't happen to everyone, but it's common" - what does this even mean? "Common" based on what criterion? How should our behaviour as a society change based on your comment?

Are you comparing psychedelics to sugar and social media? Unless psilocybin is thoroughly tested and validated as a treatment that is as safe as SSRI, I don't think it's really worthwhile to jump into the psilocybin train.

At the doses in question here, SSRIs have a terrible side effect profile when compared with psilocybin.

Re: Psilocybin 'promising' for depression

#156

Post by collyw »

nmca wrote: post #143
collyw wrote: post #133

Earlier quoted context omitted.

I didn't say they do nothing, lockdowns clearly cause massive harm and suffering yet there is no obvious benefit when compared to places that didn't lock down. https://www.nature.com/articles/s41598-021-84092-1

I've seen this claim bandied about, but if you look at Sweden and its neighbors the no-lockdown case has 1000s more deaths. There are perhaps subtle arguments, but "no obvious benefit" seems extremely tenuous.

Do you know what Finland and Norways lockdown involved?

They closed schools and public buildings. They didn't force people to stay at home. They didn't stop people travelling, or force them to wear masks. They treated their populations as humans. Their responses were a lot closer to Sweden than to most European countries "lockdown" responses.

And did you know that for whatever reason, Finland has 5 times more flu deaths per capita than Sweden on a normal year.

https://www.worldlifeexpectancy.com/cause-of-death/influenza...

You will also notice the the two countries where masks are apparently the norm, South Korea and Japan have relatively high rates of flu death for developed countries. That implies that the masks don't help.

To use Sweden as an example of lockdown being effective is grasping at straws.

Where is the spike after Texas opened up a month ago? Why is Florida doing better than California, despite an older population?

Re: Psilocybin 'promising' for depression

#157

Post by pbadenski »

jokoon wrote: post #151
pbadenski wrote: post #99

Earlier quoted context omitted.

This type of empty fear mongering comment is unhelpful at best. It's a McDonalds of a comment. What's a lot of people? Why are psychedelics so special compared to anything else (sugar, Facebook, gambling). "It doesn't happen to everyone, but it's common" - what does this even mean? "Common" based on what criterion? How should our behaviour as a society change based on your comment?

Are you comparing psychedelics to sugar and social media? Unless psilocybin is thoroughly tested and validated as a treatment that is as safe as SSRI, I don't think it's really worthwhile to jump into the psilocybin train.

In a sense, yes - I believe the damaging effects of sugar and social media on the society is far greater than psychedelics might have if decriminalised.

They definitely don't deserve to be Class A in the UK and Schedule I in the US. Even more so, they shouldn't be classified as Schedule I by the United Nations.

I'm not sure about using it regularly, but people have been using these for ceremonies for centuries. I personally believe the choice should be left with an individual.

Re: Psilocybin 'promising' for depression

#158

Post by whalesalad »

For those curious: you can cultivate your own at home. It’s 100% legal to purchase psilocybin spores online in many states.

I just had to throw out a grow due to contamination - super frustrating setback - but I’m determined to produce a healthy harvest.

Re: Psilocybin 'promising' for depression

#159

Post by Fricken »

ButtSpark69 wrote: post #20
Gatsky wrote: post #15

The study was just published in the most prestigious medical journal in the world [1]. Whatever you think of the study, this is rather significant. If you told me even 2 years ago there would be a randomised trial of magic mushrooms in NEJM, I would not have believed it for even a second. One point not to miss is that they screened 1000 patients to come up with the study population of 59. Nevertheless, I consider the…

"If you told me even 2 years ago there would be a randomised trial of magic mushrooms in NEJM, I would not have believed it for even a second." In a lot of ways, that's completely depressing for how slowly we've come as a species.

"The species" has been using psychedelics in religious ceremonies for a long time. We're just out of the loop.

Re: Psilocybin 'promising' for depression

#160

Post by agumonkey »

alexf95 wrote: post #52

I feel like there will also people that have way too many prejudices towards these kinds of "drugs" because that's simply how we learned it. "Don't take drugs kids". These studies are very helpful especially when shared over general media, but the consumption has to be supervised and controlled to not have overdoses and ruin the whole reputation again. It should be treated like any other anti-depressant, since they a…

Just show how much medicine is derived from naturally occuring molecules. Shrooms, flower or chemlab.. same same.
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