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EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

reuters.com

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Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#131

Post by IAmEveryone »

krzyk wrote: post #68
gnfargbl wrote: post #32

Earlier quoted context omitted.

> Don't subsidize drugs/vaccines that don't work. Both AZ and J&J have been proven effective. They clearly work. It might not be politically expedient for the EU Commission to emphasize that fact, but it is true nevertheless.

They work, but at least AZ is working hard to NOT deliver vaccines to EU. (and sending those manufactured in EU to the UK). Remember when Italians found 15M vaccines at the factory? I don't know why AZ representatives aren't prosecuted for such behavior of the company. So I think it is a good call to wait for the contract to end. BTW. Work at ~72%, mRNAs are at ~91%. What would you choose if you had both at the table…

"The food is terrible, and the portions much too small".

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#132

Post by tempestn »

DominikD wrote: post #104

If or when this happens, I hope we don't end up with millions of people who got the frist AZ shot and are left without access to the second dose.

All evidence suggests people will be at least as well off getting an mRNA vaccine for the second dose after an AZ first dose.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#133

Post by megous »

tpm wrote: post #101
andy_ppp wrote: post #93

Earlier quoted context omitted.

Source?

"The Danish Health Authority said studies had shown a higher than expected frequency of blood clots following doses, affecting about one in 40,000 people." https://www.bbc.com/news/world-europe-56744474

3 cases don't make a frequency, yet

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#134

Post by fshbbdssbbgdd »

polack wrote: post #91
boringg wrote: post #55

Seems short sighted to me given we don't know efficacy against the variants. If I were in the contractual chair I'd keep all my options on the table, we aren't out of this yet. assuming this is true, as opposed to some kind of way to leverage better terms out of a deal

The EU have options to buy 100 million doses of AZ vaccine for 2022, but they need to make up their minds now if they want them or not. With AZ's history of not delivering on time I think this is a no-brainer, especially since we don't know if the AZ vaccine will work on the new Covid variants. Why pour more money down the AZ drain when we have better alternatives?

Because it’s a very small amount of money relative to the impact of the pandemic. Even if these vaccines only added 1% to the fight against the pandemic they’d be worth it. This is another expression of the “penny wise, pound foolish” decision-making process that led to the EU being last in lines for the vaccines in the first place.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#135

Post by Imnimo »

hef19898 wrote: post #124
selectodude wrote: post #105

Earlier quoted context omitted.

J&J and AZ adenovirus-vector covid vaccines are highly novel vaccines that are very similar to mRNA vaccines, just with a different delivery mechanism.

Adeno virus based vector vaccines are a pretty old idea.

I was under the impression that adenovirus vaccines have only been been approved in the past year or two - a few for Ebola and the new ones for Covid. Are there others that have been around before that?

It doesn't seem like it really matters if adenovirus vector vaccines is an "old idea" - after all, the idea of using MRNA has also been around for a long time. But if we've only started actually using them recently, how different is our knowledge of long-term effects?

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#136

Post by boringg »

fshbbdssbbgdd wrote: post #134
polack wrote: post #91

Earlier quoted context omitted.

The EU have options to buy 100 million doses of AZ vaccine for 2022, but they need to make up their minds now if they want them or not. With AZ's history of not delivering on time I think this is a no-brainer, especially since we don't know if the AZ vaccine will work on the new Covid variants. Why pour more money down the AZ drain when we have better alternatives?

Because it’s a very small amount of money relative to the impact of the pandemic. Even if these vaccines only added 1% to the fight against the pandemic they’d be worth it. This is another expression of the “penny wise, pound foolish” decision-making process that led to the EU being last in lines for the vaccines in the first place.

It's the cost centric/money spent only mentality that pervades the minds of many. Agree completely with you.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#137

Post by JumpCrisscross »

seriousquestion wrote: post #96
zarkov99 wrote: post #74

Earlier quoted context omitted.

How about all the other people who did not get covid but also stayed home? Shouldn't they all be complaining about fatigue and brain fog? Come on.

They do, and would if asked! Question: Do you feel more fatigued over the past year? Common Answer: Yes. Question: Are you having a harder time concentrating or focusing? Common Answer: Yes.

> They do, and would if asked!

Today I learned I must have fatigue and brain fog...

What delusionally contrived nonsense.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#138

Post by donretag »

parhamn wrote: post #26

Does anyone know how reusable the mRNA infrastructure is in the future for other mRNA based solutions or is this stuff more one-off for COVID?

mRNA is a decade in the making, which is why they were able to target/isolate a COVID-19 vaccine is a very short time. Two weeks I believe, someone please correct me.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#139

Post by josiea »

physicsguy wrote: post #62
jleyank wrote: post #36

Probably every drug has risks, many higher than the 1:1,000,000 reported for AZ/J&J. It's always a balance between the risk untreated vs. treated - many cancer drugs will kill you, but slower than they kill the cancer. Contraceptives have various issues, but their "social good" is deemed worthwhile. I've read that they are doing gene analysis to try and determine why these cases appear - is it gender, age, cross-reac…

On top of that, we wouldn't even yet know if there were any long term side effects from Pfizer, etc.

The publication to follow is the CDC Advisory Committee on Immunization Practices (ACIP) monthly reports. There's a report from January and one latest is from March 1.

So far no statistically significant adverse events have occured for either pfizer or moderna vaccines. I follow them closely.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#140

Post by andy_ppp »

megous wrote: post #133
tpm wrote: post #101

Earlier quoted context omitted.

"The Danish Health Authority said studies had shown a higher than expected frequency of blood clots following doses, affecting about one in 40,000 people." https://www.bbc.com/news/world-europe-56744474

3 cases don't make a frequency, yet

I think I read 10 somewhere but as I’ve said in the sibling comment it’s hard to know if these were all weird cases like the one who died or if they fit a pattern at all.
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