EU Commission to end AstraZeneca and J&J vaccine contracts at expiry • Hacker News Board

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#91

Post by polack » Wed, Apr 14, 2021, 3:57 PM UTC

boringg wrote: post #55

Seems short sighted to me given we don't know efficacy against the variants. If I were in the contractual chair I'd keep all my options on the table, we aren't out of this yet. assuming this is true, as opposed to some kind of way to leverage better terms out of a deal

The EU have options to buy 100 million doses of AZ vaccine for 2022, but they need to make up their minds now if they want them or not. With AZ's history of not delivering on time I think this is a no-brainer, especially since we don't know if the AZ vaccine will work on the new Covid variants. Why pour more money down the AZ drain when we have better alternatives?

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#92

Post by krona » Wed, Apr 14, 2021, 3:59 PM UTC

quantgenius wrote: post #70

jleyank wrote: post #36

Probably every drug has risks, many higher than the 1:1,000,000 reported for AZ/J&J. It's always a balance between the risk untreated vs. treated - many cancer drugs will kill you, but slower than they kill the cancer. Contraceptives have various issues, but their "social good" is deemed worthwhile. I've read that they are doing gene analysis to try and determine why these cases appear - is it gender, age, cross-reac…

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I suggest you do more reading and less writing.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#93

Post by andy_ppp » Wed, Apr 14, 2021, 4:02 PM UTC

tpm wrote: post #88

jleyank wrote: post #36

Probably every drug has risks, many higher than the 1:1,000,000 reported for AZ/J&J. It's always a balance between the risk untreated vs. treated - many cancer drugs will kill you, but slower than they kill the cancer. Contraceptives have various issues, but their "social good" is deemed worthwhile. I've read that they are doing gene analysis to try and determine why these cases appear - is it gender, age, cross-reac…

Denmark reports AZ's serious blood clotting issue as up to 1:40'000. I will still get vaccinated with it if it's available in our country for me as I think the risk is worth it in my case. But if I was a woman under 60 and especially under 40 I would be hesitant to get vaccinated with AZ and probably wait for other vaccine.

Source?

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#94

Post by [deleted] » Wed, Apr 14, 2021, 4:04 PM UTC

tpm wrote: post #88

jleyank wrote: post #36

Probably every drug has risks, many higher than the 1:1,000,000 reported for AZ/J&J. It's always a balance between the risk untreated vs. treated - many cancer drugs will kill you, but slower than they kill the cancer. Contraceptives have various issues, but their "social good" is deemed worthwhile. I've read that they are doing gene analysis to try and determine why these cases appear - is it gender, age, cross-reac…

Denmark reports AZ's serious blood clotting issue as up to 1:40'000. I will still get vaccinated with it if it's available in our country for me as I think the risk is worth it in my case. But if I was a woman under 60 and especially under 40 I would be hesitant to get vaccinated with AZ and probably wait for other vaccine.

[deleted]

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#95

Post by barrenko » Wed, Apr 14, 2021, 4:05 PM UTC

Another EU blunder, what more can be said at this point.

The only person who could pivot EU to something effective at this point would be a fictional character such as Darth Vader.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#96

Post by seriousquestion » Wed, Apr 14, 2021, 4:06 PM UTC

zarkov99 wrote: post #74

seriousquestion wrote: post #58

Earlier quoted context omitted.

Long Covid is mostly self reported vague symptoms, namely fatigue and brain fog. It's what happens when you stay at home too much and don't get enough exercise and have a poor diet. Isolation? The Covid 15* that many of us packed on? You will feel worse and especially more fatigued, no doubt. Not to mention being constantly immersed in an environment of fear. It's a misattribution to associate side effects of weight…

How about all the other people who did not get covid but also stayed home? Shouldn't they all be complaining about fatigue and brain fog? Come on.

They do, and would if asked!

Question: Do you feel more fatigued over the past year?

Common Answer: Yes.

Question: Are you having a harder time concentrating or focusing?

Common Answer: Yes.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#97

Post by solarkraft » Wed, Apr 14, 2021, 4:08 PM UTC

I hope this isn't true unless an mRNA vaccine production miracle is inbound.

This will measure whether the commission has

a) Managed to solve the self-inflicted supply issues far beyond demand

or

b) Lost the last bit of sanity.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#98

Post by cm2187 » Wed, Apr 14, 2021, 4:10 PM UTC

shlant wrote: post #89

bmj wrote: post #82

Earlier quoted context omitted.

Except this particular vaccination mechanism (mRNA) has never been licensed for use in humans. Yes, there has been research, but never any sort of trial on the scale of what is happening right now. So, we really don't know what the long term effects of this particular type of vaccine are. I'm not trying to cast doubt on the efficacy of the vaccines that have been approved. Rather, I'm simply pointing out we don't hav…

yes you are correct that we don't really know until we know, but there is good reason to believe that mRNA vaccines are actually safer than traditional methods https://www.hsph.harvard.edu/news/multimedia-article/were-be... This seems to be at least partially supported by the current risks in regards to currently available non-mRNA vaccines (such as AZ). Also I'm not really sure what saying "we don't know the long te…

The conversation is about the respective merits of one vaccine over another. The fact that one is a new approach with no long term data on humans whether the other is a traditional approach is relevant.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#99

Post by josefx » Wed, Apr 14, 2021, 4:10 PM UTC

jleyank wrote: post #36

Probably every drug has risks, many higher than the 1:1,000,000 reported for AZ/J&J. It's always a balance between the risk untreated vs. treated - many cancer drugs will kill you, but slower than they kill the cancer. Contraceptives have various issues, but their "social good" is deemed worthwhile. I've read that they are doing gene analysis to try and determine why these cases appear - is it gender, age, cross-reac…

This might just be the straw that broke the camels back. As far as I remember the contracts the EU signed turned out to be incredibly one sided, with deliveries getting cut down when someone found out that more dosages could be extracted, no hard delivery requirements leading to constant shortages, etc. . Not getting out of that mess when alternatives exist seems like a bad idea.

Re: EU Commission to end AstraZeneca and J&J vaccine contracts at expiry

#100

Post by bhobs » Wed, Apr 14, 2021, 4:14 PM UTC

quantgenius wrote: post #70

jleyank wrote: post #36

Probably every drug has risks, many higher than the 1:1,000,000 reported for AZ/J&J. It's always a balance between the risk untreated vs. treated - many cancer drugs will kill you, but slower than they kill the cancer. Contraceptives have various issues, but their "social good" is deemed worthwhile. I've read that they are doing gene analysis to try and determine why these cases appear - is it gender, age, cross-reac…

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I didn't expect to find this level of, frankly, absolute nonsense on HN. Please don't write fabricated statistics which have no basis in reality. It's dangerous to present such misinformation.