Live data from Hacker News

Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

jamanetwork.com

21–30 of 267 posts

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#21
post #17

The immune system still works as advertised.

What’s the purpose of comments like this? EDIT: I see someone mentioning Trump below and I can’t reply. Trump was never interested in managing covid-19 or effective border control. This would’ve been the perfect opportunity for him to show why having smart borders was useful. He would’ve received support from within the government. He would’ve managed covid-19 successfully perhaps, and won re-election. The problem wa…

Probably that patience has worn thin for the extremely overly cautious people who have been hiding in their homes for a year when they are realistically at zero risk of severe illness.

We have known since early summer of last year that being fat or being old are your two biggest risk factors. Beyond that, if you have some serious pre-existing condition that makes you susceptible to all illnesses.

The messaging should have been "Stay home if you are a high risk group. Otherwise live your live." All current data shows areas that have taken that approach are significantly better off today than the places that hid in a hole the past year.

We have let people treat this like it's an end of the world scenario and it's been good for no one.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#22

The title of this article, which performs an in vitro test, is "Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination". The editorialization in the current Hacker News headline ("Vaccines Are Effective Against Covid Variants") is not warranted.

In other words it’s a little early to start the victory chants.

Unfortunately this will get used to justify reckless behavior.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#23

The title of this article, which performs an in vitro test, is "Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination". The editorialization in the current Hacker News headline ("Vaccines Are Effective Against Covid Variants") is not warranted.

If I can pass on what I’ve learned in the past 12 months as a newly minted virus enthusiast whose peak education in the area was human physiology 101:

“In vitro” means testing outside of the human body. Just because a result is confirmed in vitro does not mean it will be replicated when tested “in vivo” (in the actual human).

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#24
post #21
post #17

Earlier quoted context omitted.

What’s the purpose of comments like this? EDIT: I see someone mentioning Trump below and I can’t reply. Trump was never interested in managing covid-19 or effective border control. This would’ve been the perfect opportunity for him to show why having smart borders was useful. He would’ve received support from within the government. He would’ve managed covid-19 successfully perhaps, and won re-election. The problem wa…

Probably that patience has worn thin for the extremely overly cautious people who have been hiding in their homes for a year when they are realistically at zero risk of severe illness. We have known since early summer of last year that being fat or being old are your two biggest risk factors. Beyond that, if you have some serious pre-existing condition that makes you susceptible to all illnesses. The messaging should…

So you’d prefer we be like Brazil?

Because the alternative for us was not Taiwan or Korea. They went far and beyond what Americans were willing to tolerate.

Never mind the bad statistics behind your claim that covid is no worse than the flu. A athlete friend of mine in his 20s has permanent heart damage caused by the virus. Covid-19 is not a joke, no matter how much you wish it was.

Americans could be out free, today, if we took this virus more seriously from the start. Now people like you want to make the disease endemic when the end is in sight.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#25
post #21
post #17

Earlier quoted context omitted.

What’s the purpose of comments like this? EDIT: I see someone mentioning Trump below and I can’t reply. Trump was never interested in managing covid-19 or effective border control. This would’ve been the perfect opportunity for him to show why having smart borders was useful. He would’ve received support from within the government. He would’ve managed covid-19 successfully perhaps, and won re-election. The problem wa…

Probably that patience has worn thin for the extremely overly cautious people who have been hiding in their homes for a year when they are realistically at zero risk of severe illness. We have known since early summer of last year that being fat or being old are your two biggest risk factors. Beyond that, if you have some serious pre-existing condition that makes you susceptible to all illnesses. The messaging should…

I'm a healthy male who's been "hiding in [my] home for a year". I mean, other than shopping trips, and running, and cycling, and skiing, and.. However, I've done no social events, seen no friends, etc.

But, sorry if you think trying to avoid illness, trying to avoid passing on illness to others who don't have the comfort of working from home, passing on the illness to elderly family members, etc, is a waste of time. It's a pretty minor inconvenience for me to be largely isolated for a year, compared to those who are less fortunate than me.

How about a big 'ol [citation needed] on

> All current data shows areas that have taken that approach are significantly better off today than the places that hid in a hole the past year.

You know, a citation that doesn't involve correlation with countries that happened to have extreme lockdowns initially, acceptance of mass testing and screening and social restriction when necessary, etc.

By the way, my wife works in rehab in a hospital, and sees your "low risk" young people whose lives have been, as far as we can tell, permanently altered by the virus that some of us are seeking to avoid.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#26
post #21
post #17

Earlier quoted context omitted.

What’s the purpose of comments like this? EDIT: I see someone mentioning Trump below and I can’t reply. Trump was never interested in managing covid-19 or effective border control. This would’ve been the perfect opportunity for him to show why having smart borders was useful. He would’ve received support from within the government. He would’ve managed covid-19 successfully perhaps, and won re-election. The problem wa…

Probably that patience has worn thin for the extremely overly cautious people who have been hiding in their homes for a year when they are realistically at zero risk of severe illness. We have known since early summer of last year that being fat or being old are your two biggest risk factors. Beyond that, if you have some serious pre-existing condition that makes you susceptible to all illnesses. The messaging should…

> All current data shows areas that have taken that approach are significantly better off today than the places that hid in a hole the past year.

Source?

I'd argue current data shows that those that showed an overabundance of caution, like New Zealand, are the ones significantly better off than everyone else.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#27
post #13
post #7

A January 2021 study in the annals of internal medicine estimating the death rates of non institutionalized patients of .26 percent with age breakdowns . https://www.acpjournals.org/doi/10.7326/M20-5352?utm_source=...

For every person that dies (an agonizing death akin to medieval torture), a few more are in intensive care fighting for their lives. For every one of those, others end up in the hospital, spread the disease to others, suffer from “long covid”, or merely suffer greatly. Every person that gets covid adds to the likelihood the disease will become uncontrollable in the long term and endemic. Keep wearing your masks and s…

> For every person that dies (an agonizing death akin to medieval torture)

I think this is wrong, at least in rich countries, at least those that are sane enough to cure their ill citizens.

A friend of mine died of covid last year. Then a family member this year. They were both sedated, and did not suffer at all on their last days in hospitals.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#28
post #21
post #17

Earlier quoted context omitted.

What’s the purpose of comments like this? EDIT: I see someone mentioning Trump below and I can’t reply. Trump was never interested in managing covid-19 or effective border control. This would’ve been the perfect opportunity for him to show why having smart borders was useful. He would’ve received support from within the government. He would’ve managed covid-19 successfully perhaps, and won re-election. The problem wa…

Probably that patience has worn thin for the extremely overly cautious people who have been hiding in their homes for a year when they are realistically at zero risk of severe illness. We have known since early summer of last year that being fat or being old are your two biggest risk factors. Beyond that, if you have some serious pre-existing condition that makes you susceptible to all illnesses. The messaging should…

| they are realistically at zero risk of severe illness.

I didn't do it for me.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#29
post #3

It seems that the AstraZeneca vaccine is not effective against the South African variant [0]. [0]: https://www.nejm.org/doi/full/10.1056/NEJMoa2102214?fbclid=I...

That's wrt mild to moderate cases. It might still be effective against severe cases.

good point, it might raise our IQ as well!

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#30
post #13
post #7

A January 2021 study in the annals of internal medicine estimating the death rates of non institutionalized patients of .26 percent with age breakdowns . https://www.acpjournals.org/doi/10.7326/M20-5352?utm_source=...

For every person that dies (an agonizing death akin to medieval torture), a few more are in intensive care fighting for their lives. For every one of those, others end up in the hospital, spread the disease to others, suffer from “long covid”, or merely suffer greatly. Every person that gets covid adds to the likelihood the disease will become uncontrollable in the long term and endemic. Keep wearing your masks and s…

I don’t see any reason new variants would ever stop coming. What are you proposing is the end point of all of this?
Post reply on HN