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Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

sciencenorway.no

181–190 of 288 posts

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#181

Earlier quoted context omitted.

Cars should also be banned and replaced with alternatives (be it safe self driving tech, public transit or biking). Car crashes are one of the top killers of young people in terms of crashes, and we’re just starting to understand the effects of air pollution on young lungs.

Or maybe stop banning things and let people make their own decisions.

What about WMDs? Where do you suggest we draw the line?

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#182
post #151

Earlier quoted context omitted.

In Norway, five women below 50 years have died of COVID-19 (in total) and one from the vaccine Source (in English): https://www.fhi.no/en/id/infectious-diseases/coronavirus/dai...

But did these women have any comorbidities?

The sample is so small that even if they did it wouldn't be possible to say anything definitive about any possible connection. The death rate here in Norway is minuscule compared to the UK, US, France, etc.

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#183
post #135

The rate of blood clots as a side effect for the AZ covid jab is less than that of the combined contraceptive pill - does that mean that both need to be discontinued?

The clotting with AZ is very different and more serious than what the thrombosis associated with the pill - about half of those who get it die even with best medical care. It predominanctly affects folks who would have a miniscule risk of death by Covid19, so this absolutely needs to be investigated.

So why not prescribe aspirin until say a month after the second dose.

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#184

The rate of blood clots as a side effect for the AZ covid jab is less than that of the combined contraceptive pill - does that mean that both need to be discontinued?

In addition to the severity of the clots, the difference is that the side-effect is not expected and not mentioned in the patient information.

Quote from the German PEI institute [1]:

> It is true that for birth control pills thromboses, even with fatal outcome, are known as a very rare side effect. They are listed in the Summary of Product Characteristics (SmPC). The birth control pill is available only on prescription. Every woman must be informed of this risk by the prescribing physician. For the COVID-19 Vaccine AstraZeneca, there is currently a suspected very rare side effect of sinus vein thrombosis with accompanying platelet deficiency, sometimes fatal. It is not listed in the SmPC.

The whole statement is quite informative: [1] https://www.pei.de/EN/service/faq/coronavirus/faq-coronaviru...

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#185
post #135

The rate of blood clots as a side effect for the AZ covid jab is less than that of the combined contraceptive pill - does that mean that both need to be discontinued?

The clotting with AZ is very different and more serious than what the thrombosis associated with the pill - about half of those who get it die even with best medical care. It predominanctly affects folks who would have a miniscule risk of death by Covid19, so this absolutely needs to be investigated.

I saw the description by the doctor who treated the person who died here in Norway. He called it a "catastrophe in the brain" [1] and the life just could not be saved.

It sounds really nasty. Blood clots + low blood plate count at the same time.

[1] https://www.nrk.no/norge/innlagt-helsearbeider-dode-_-unders...

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#186
post #53
post #42

Earlier quoted context omitted.

Yes, but, there are close to 200 vaccines. It isn't as if all vaccinations have stopped, there are other options, and panic and fear on the side of omg must vaccinate now, now,now! ? Any hint, even the slightest, that complications may be ignored, could result in untold masses refusing vaccination out of fear. So let's pause one vaccine for a few days, and see if moving ahead, or more research is required.

> there are other options Not with sufficient supply there isn’t. That’s the issue almost every country is facing, and AZ production plants can’t just flip a switch and start making Moderna vaccines instead. No matter what if you stop using the AZ you’re going to have a sharp drop in the number of vaccinations you’re able to do. That would almost certainly result in more deaths than the side effect of the vaccine. >…

AstraZeneca isn't even approved in the US yet so the delay will most likely have no effect there.

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#187
post #135

Earlier quoted context omitted.

The clotting with AZ is very different and more serious than what the thrombosis associated with the pill - about half of those who get it die even with best medical care. It predominanctly affects folks who would have a miniscule risk of death by Covid19, so this absolutely needs to be investigated.

So why not prescribe aspirin until say a month after the second dose.

Because aspirin has no meaningful impact on as severe an autoimmune platelet implosion as is described in these cases.

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#188
post #49

Earlier quoted context omitted.

Maybe I've missed it, but I didn't find anything in the article about whether the vaccine does need to be discontinued or not. In any case, being clear about what side effects are possible and researching them to get a better understanding is a requirement in my opinion.

You need to read the VG articles, they are much more thorough than the one linked on HN but they are in Norwegian. Google Translate does a fair job. https://www.vg.no/nyheter/innenriks/i/QmwR1V/professor-om-mi... https://www.vg.no/nyheter/innenriks/i/KyWoy6/jakter-astrazen... A key quote from the second of those is this: Madsen har tidligere forklart at det er to nivåer å undersøke bivirkninger på: Gruppebasert, og i…

This comment should not be downvoted as it is both topical and helpful.

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#189

Earlier quoted context omitted.

It's still too early for the general public to draw conclusions from the data provided. Derek Lowe had some early observations on these numbers and their significance in regards to the critical missing data needed to make decisions: https://blogs.sciencemag.org/pipeline/archives/2021/03/16/wh... > "...they say that is indeed “ much lower than would be expected to occur naturally in a general population of this size “…

Derek did a good job on this issue, both warning it would happen before and re-emphasizing that it's most likely statistical anomaly. Even if the blood clots were a result of the AZ vaccine, it would still make more sense for most people to take the vaccine (I would), so a ban is entirely unjustified. Governments banning their citizens from taking Astrazeneca should use accurate language "it's banned" instead of the…

I guess I'll take my 2.35e-6 chance (40 in 17M) to get blood clots over a 1.6e-3 chance to contact covid (4‰ infection rate) and die from it (4% mortality rate).

Re: Norwegian experts say blood clots were caused by the AstraZeneca Covid vaccine

#190
post #140

Earlier quoted context omitted.

> we found specific antibodies against blood platelets So are they claiming that this is actually due to the vaccine formulation itself, i.e. does this finding exclude the initial hypothesis of a Quality issue or a specific 'bad batch' of the vaccine?

the news article doesn't say; it attributes a quote to the doctor saying "it's the vaccine" but it's unclear whether that means "bad batch". Personally, if 3 health workers all go to the same hospital in a remote region complaining of clots, it's more likely that something local happened (as you say, QA, or any number of other sources).

The article is a very poor quality summary. The articles in VG are much better. I put a quote from one and a translation elsewhere on this HN page.
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