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Vaccines should end the pandemic, despite the variants, say experts

news.harvard.edu

101–110 of 370 posts

Re: Vaccines should end the pandemic, despite the variants, say experts

#101

FYI, Galit Alter has conflict of interest with Bill and Melinda Gates foundation: https://seromyx.com

How do you have a conflict of interest with a non profit?

I'm not sure what the person you're replying to is talking about but it sounds pretty easy to have a conflict of interest.

If a non profit is doing something for free that a company is charging for, anything they say about the non-profit should be observed with caution.

Re: Vaccines should end the pandemic, despite the variants, say experts

#102
post #100
post #88

Earlier quoted context omitted.

Because no two fields are alike? We don't do anything even remotely scientifically in this industry because it's one of the few where we don't need to for various reasons

Basically compare how software is developed by all of us to how software was written for the space shuttle. There is just absolutely no comparison in process or methodology. Space shuttle programming is what true software engineering looks like.

I've always thought that true engineering is anything that involves human lives. Bridges, pipes, roads, pace makers, space ships, rockets. Websites don't kill people, it ain't engineering.

Re: Vaccines should end the pandemic, despite the variants, say experts

#103

Earlier quoted context omitted.

That also depends what "normal" means to you. If normal just means you get to hug your grandmother who lives an hour away it might be safe right now (in a bunch of countries) or permitted but perhaps unwise (in a lot more countries) and it's likely that for most HN readers it will become a reasonable thing to do around mid-2021. If it means snogging random strangers at a crowded nightclub after a night of drinking th…

> "If it means snogging random strangers ... might not be a reasonable thing to do until late 2021 or after for most of us" 7000 people ages 18-39 have dies of covid19 in the U.S. [0][1]. There's at least 75 million people in that age group! (maybe more, sorry no handy/easy/exact reference) That's 1 in 10,000 odds of dying for that age group. They are 20 times more likely to die of something else. I think it is unrea…

1 in 10,000 is the death rate so far, not the individual odds of dying if everyone in the age group gets sick.

Re: Vaccines should end the pandemic, despite the variants, say experts

#104
post #34

Earlier quoted context omitted.

I can't believe you are getting downvoted! This is a real risk! Relevant quote: > Under normal conditions, highly virulent strains of the virus are not selected. A highly virulent strain would kill the host before the virus would have an opportunity to transmit to other potential hosts and replicate. Thus, less virulent strains are selected. These strains are virulent enough to induce symptoms but not enough to kill…

> This is a real risk! I never heard this discussed as a big "risk". As far as I know this was always more or less known to be the endgame and not even a dangerous outcome but the "good" scenario. Once it's an established coronavirus, it can be like the other known human coronaviruses we already have. The reason you don't die from OC43 at age 75 now is because you probably cought it a few times before that. It's not…

There’s a theory published in some academic research in virology about OC43 possibly being what caused the 1889-1890 “flu” pandemic

Re: Vaccines should end the pandemic, despite the variants, say experts

#105

What nobody wants to talk about is that it might take several more years for things to go back to somewhat normal. https://www.thelancet.com/journals/lancet/article/PIIS0140-6... >In developing its COVID-19 Scenarios Project, the ISC has consulted with WHO and the UN Office for Disaster Risk Reduction. The ISC has established in February, 2021, a multidisciplinary Oversight Panel made up of globally representative wo…

> it might take several more years for things to go back to somewhat normal. People always make statements like this, but nobody defines what "normal" actually means. Some things will probably never go back to the way they were. Does that mean things won't be "normal"? Normal also means entirely different things for different countries and different individuals. That's why I dislike statements like this, unless there…

Let's define normal as, no lockdowns, no business restrictions, public gathering restrictions, public activity restrictions, and no mask requirements.

Re: Vaccines should end the pandemic, despite the variants, say experts

#106
post #68

What I don't understand is this: with tens of millions of people already vaccinated, why aren't we seeing a huge drive to collect plasma from vaccinated people with high level of antibodies? In the early days of the pandemic (about 1 year ago), I remember China sent a large amount of plasma to Italy. Why can't the US do the same now? The US is sitting on millions of AstraZeneca vaccines (that are not even approvad by…

The United States has administered 2.3 million vaccination doses. Oh, lol no, not cumulatively. I mean Yesterday. We administered 2.3 million doses in about 14 daytime hours on March 12th. Naturally, the number of vaccinated individuals grows every day. That's what vaccinations do. But the number of doses we are administering every day is growing every day. One week ago, on March 8th, we administered about 2.05 milli…

The US has bought its way out of the pandemic by funding the pharma companies and reserving doses.

This was a smart play, of course, and ultimately the deciding factor, but this success is only being realized after a long string of failures and ongoing inefficiencies.

Re: Vaccines should end the pandemic, despite the variants, say experts

#107

Earlier quoted context omitted.

> "If it means snogging random strangers ... might not be a reasonable thing to do until late 2021 or after for most of us" 7000 people ages 18-39 have dies of covid19 in the U.S. [0][1]. There's at least 75 million people in that age group! (maybe more, sorry no handy/easy/exact reference) That's 1 in 10,000 odds of dying for that age group. They are 20 times more likely to die of something else. I think it is unrea…

1 in 10,000 is the death rate so far, not the individual odds of dying if everyone in the age group gets sick.

Sure, but its the data we have, and therefore the best estimate we have of the likelihood, on average.

Re: Vaccines should end the pandemic, despite the variants, say experts

#108
post #95
post #68

Earlier quoted context omitted.

The United States has administered 2.3 million vaccination doses. Oh, lol no, not cumulatively. I mean Yesterday. We administered 2.3 million doses in about 14 daytime hours on March 12th. Naturally, the number of vaccinated individuals grows every day. That's what vaccinations do. But the number of doses we are administering every day is growing every day. One week ago, on March 8th, we administered about 2.05 milli…

>US will be one of the first countries back to normalcy I live in Australia. The country has been to normal for a long time now, and my state specifically had a lockdown at the start of the pandemic, and since August 2020, we have not had a major lock down (except for one week in Jan 2021 due to a outbreak scare) and have been living in normalcy since then. Just saying because it seems like people erasing and forgett…

New Zealand comes to mind as well.

Re: Vaccines should end the pandemic, despite the variants, say experts

#109
post #46

Earlier quoted context omitted.

Don’t remember the study but pretty sure that cross reactivity thesis to common cold eventually didn’t pan out. Believe Derek Lowe wrote about it.

https://blogs.sciencemag.org/pipeline/archives/2021/02/10/do... > But here’s the key part: “cross-react” does not mean “neutralize” and it does not mean “provide protection from”. These antibodies may or may not have been neutralizing against the other coronaviruses, but they don’t seem to have any such effect on the current one. And in keeping with that, having such cross-reactive antibodies seems to provide no prot…

Yes, the topic of discussion is T-cells, NOT antibodies.

Re: Vaccines should end the pandemic, despite the variants, say experts

#110
I hope they are correct.

I also hope we will continue to be more careful about germ control from here on out in myriad ways. I hope we do not blithely go back to "business as usual" in a way that fosters future pandemics as if we learned absolutely nothing here.

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