Instead, let's bring back the lunchbox form factor. A mini motherboard with a real desktop processor, a little bit of expansion for a larger graphics card or extra storage, and a full-size keyboard. Since we don't need the front-facing floppy disk slots of the past, we can make the monitor the full width of the front, but have it backing on a more sizable chassis that contains most of the processing power. A really nice webcam, even room for a good condenser mic and better speakers, plus plenty of expansion ports instead of the typical "whatever fits on the knife edge of the razor profile" selection.
Think iMac, but smaller and with a keyboard that just snaps or folds into the monitor like a laptop, and with a solid battery so you don't have to plug it in if you don't want to.