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Meat consumption and risk of 25 conditions: outcome-wide analyses of 475K people

bmcmedicine.biomedcentral.com

1–10 of 281 posts

Re: Meat consumption and risk of 25 conditions: outcome-wide analyses of 475K people

#3
The term "positive association" makes it hard to parse. The results state: "most of the positive associations observed for meat consumption and health risks were substantially attenuated after adjustment for body mass index (BMI)", but the Conclusion says:

> Higher unprocessed red meat, processed meat, and poultry meat consumption was associated with higher risks of several common conditions; higher BMI accounted for a substantial proportion of these increased risks suggesting that residual confounding or mediation by adiposity might account for some of these remaining associations. Higher unprocessed red meat and poultry meat consumption was associated with lower IDA risk.

So basically 'Red meat is fine but we found a correlation between heart disease and obesity'?

Re: Meat consumption and risk of 25 conditions: outcome-wide analyses of 475K people

#6
So it seems that high BMI / adiposity is still the leading cause for those 25 adverse health outcomes and that high meat consumption is simply correlated with high total energy consumption.

It will be interesting to see if WHO revise its recommendations regarding meat consumption.

Re: Meat consumption and risk of 25 conditions: outcome-wide analyses of 475K people

#7

So... don't eat processed meat. Doesn't this just correlate with what we already knew?

I'm not sure what the conclusion of this study is, but I'd like to point out that it is not the role of science to be controversial or surprising. It's really a pity that researchers who get non-exciting results feel like they've failed.

Re: Meat consumption and risk of 25 conditions: outcome-wide analyses of 475K people

#8

So it seems that high BMI / adiposity is still the leading cause for those 25 adverse health outcomes and that high meat consumption is simply correlated with high total energy consumption. It will be interesting to see if WHO revise its recommendations regarding meat consumption.

Interesting. Maybe the new rule should be "Eat red meat if you want, just don't let it make you fat".

Re: Meat consumption and risk of 25 conditions: outcome-wide analyses of 475K people

#9
post #3

The term "positive association" makes it hard to parse. The results state: "most of the positive associations observed for meat consumption and health risks were substantially attenuated after adjustment for body mass index (BMI)", but the Conclusion says: > Higher unprocessed red meat, processed meat, and poultry meat consumption was associated with higher risks of several common conditions; higher BMI accounted for…

They have a "Role of BMI" section which strengthens your point.

> BMI accounted for a substantial proportion

In the "Role of BMI" they also say that BMI isn't perfect to detect adiposity, suggesting even further that being fat is what you want to avoid.

> Finally, given the observational nature of this study, it is possible that there is still unmeasured confounding, residual confounding, and reverse causality.

Studying human diets is hard.

Re: Meat consumption and risk of 25 conditions: outcome-wide analyses of 475K people

#10
post #3

The term "positive association" makes it hard to parse. The results state: "most of the positive associations observed for meat consumption and health risks were substantially attenuated after adjustment for body mass index (BMI)", but the Conclusion says: > Higher unprocessed red meat, processed meat, and poultry meat consumption was associated with higher risks of several common conditions; higher BMI accounted for…

No, that is not what it says.

> In multi-variable adjusted (including BMI)

So after correcting for BMI, meat consumption is still bad.

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