Biology is non-toxic. Biology is efficient. No, and no.
I would assume, knowing what I know, and presuming what he knows -- He's not saying biology/nature has no toxins. He's saying biology by and large isn't toxic to ecological systems made of average biological components. And I feel he's more right than wrong.
The efficiency thing is only right in certain domains, but really interesting ones: e.g., (1) functional state of folded proteins being an exact match with the lowest energy conformational state that it's linear amino acid order allows, (2) ecology recycling everything and re-using it all without "waste", and stuff like that.