Here's an example that came to mind:
If you were convinced psychedelic medicine is going to be huge as a sector, but also feel it's too early to pick winners/losers (and you dislike the expense overhead of PSYK) - great, make your own ETF. You still have sector risk but not 'stock picking risk'.
FYI - this is a great real example, but assumes Enomics can handle the Neo exchange (in Canada, since that's where most of the psych stocks are these days). Like, someone should post this over at /r/shroomstocks for real. :)